BCL2-Associated Athanogene 3 (BAG3) ELISA Kits

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. Additionally we are shipping BAG3 Antibodies (130) and BAG3 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
BAG3 9531 O95817
Anti-Mouse BAG3 BAG3 29810 Q9JLV1
Anti-Rat BAG3 BAG3 293524  
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Top BAG3 ELISA Kits at antibodies-online.com

Showing 6 out of 13 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.061 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$589.47
Details
Chicken 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rabbit 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Human 0.061 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 8 to 12 Days
$766.25
Details
Monkey 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details

Top referenced BAG3 ELISA Kits

  1. Human BAG3 ELISA Kit for Sandwich ELISA - ABIN418041 : Pacheco, Berra, Morais, Sciani, Branco, Bosch, Chudzinski-Tavassi: Dynein function and protein clearance changes in tumor cells induced by a Kunitz-type molecule, Amblyomin-X. in PLoS ONE 2014 (PubMed)

More ELISA Kits for BAG3 Interaction Partners

Zebrafish BCL2-Associated Athanogene 3 (BAG3) interaction partners

  1. This study therefore identifies both BAG3 reduction and autophagy promotion as potential therapies for FLNC (show FLNC ELISA Kits)(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.

  2. findings showed that the P209L mutation causes BAG3 to aggregate; proposed that the gradual loss of available BAG3(wt) and BAG3(P209L) proteins results in insufficiency leading to myofibrillar disintegration

Human BCL2-Associated Athanogene 3 (BAG3) interaction partners

  1. BAG3 directly stabilizes hexokinase 2 (show HK2 ELISA Kits) mRNA and promotes aerobic glycolysis in pancreatic cancer cells.

  2. These results indicated that at least some oncogenic functions of BAG3 were mediated through posttranscriptional regulation of Skp2 via antagonizing suppressive action of miR (show MLXIP ELISA Kits)-21-5p in ovarian cancer cells.

  3. Familial suffering of Dilated cardiomyopathy and carrying a heterozygous large deletion in the BAG3 gene.This gene encodes BCL2-associated athanogene 3 protein.

  4. BAG3 mutations are associated with DCM phenotypes. BAG3 should be added to cardiomyopathy gene panels for screening of DCM patients, and patients previously considered gene elusive should undergo sequencing of the BAG3 gene.

  5. The spatial regulation of mTORC1 exerted by BAG3 apparently provides the basis for a simultaneous induction of autophagy and protein synthesis to maintain the proteome under mechanical strain.

  6. This study therefore identifies both BAG3 reduction and autophagy promotion as potential therapies for FLNC (show FLNC ELISA Kits)(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.

  7. variants in TNNT2 (show TNNT2 ELISA Kits) and BAG3 are associated with a high propensity to life-threatening cardiomyopathy presenting from childhood and young adulthood.

  8. It has been demonstrated that HSPB8 (show HSPB8 ELISA Kits)-BAG3-HSP70 (show HSP70 ELISA Kits) ensures the functionality of stress granules and restores proteostasis by targeting defective ribosomal products for degradation.

  9. The authors propose that the chaperone-mediated autophagy function of BAG3 represents a specific host defense strategy to counteract the function of VP40 in promoting efficient egress and spread of virus particles.

  10. BAG3 bound to Hsp70 (show HSP70 ELISA Kits) at the same time as Hsp22 (show HSPB8 ELISA Kits), Hsp27 (show HSPB1 ELISA Kits), or alphaB-crystallin (show CRYAB ELISA Kits), suggesting that it might physically bring the chaperone families together into a complex.

Mouse (Murine) BCL2-Associated Athanogene 3 (BAG3) interaction partners

  1. BAG3 directly stabilizes hexokinase 2 (show HK2 ELISA Kits) mRNA and promotes aerobic glycolysis in pancreatic cancer cells.

  2. BAG3 expression is required for neuronal differentiation and migration.

  3. interaction between BAG3 and HSP70 (show HSP70 ELISA Kits) is essential for BAG3 to stabilize small heat shock proteins and maintain cardiomyocyte protein homeostasis

  4. The spatial regulation of mTORC1 exerted by BAG3 apparently provides the basis for a simultaneous induction of autophagy and protein synthesis to maintain the proteome under mechanical strain.

  5. Genetic variation in BAG3 plays an important role in the prevention of ischemic tissue necrosis.

  6. The aim of this study was to investigate the possible hemodynamic effects of BAG3 performing both in vitro and in vivo experiments.

  7. Our findings that BAG3 is localized at the sarcolemma and t-tubules while modulating myocyte contraction and action potential duration through specific interaction with the beta1-adrenergic receptor and L-type Ca(2 (show CA2 ELISA Kits)+) channel provide novel insight into the role of BAG3 in cardiomyopathies and increased arrhythmia risks in heart failure.

  8. molecular association of MyHC and BIS is necessary for MyHC stabilization in skeletal muscle.

  9. BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.

  10. Bis is upregulated in astrocytes after hypoxia-ischemia; hypoxia-ischemia induces progressive cell death in the hippocampi of bis-positive mice, while hippocampal neurons are less vulnerable to hypoxia-ischemia in mice that lack Bis.

BAG3 Antigen Profile

Antigen Summary

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Gene names and symbols associated with BAG3

  • BCL2 associated athanogene 3 L homeolog (bag3.L) antibody
  • BCL2-associated athanogene 3 (bag3) antibody
  • BCL2 associated athanogene 3 (BAG3) antibody
  • BCL2 associated athanogene 3 (bag3) antibody
  • BCL-2-associated athanogene 3 (BAG3) antibody
  • BCL2-associated athanogene 3 (Bag3) antibody
  • Bcl2-associated athanogene 3 (Bag3) antibody
  • AA407278 antibody
  • ATBAG3 antibody
  • BAG-3 antibody
  • BAG3 antibody
  • bag3-A antibody
  • BCL-2-associated athanogene 3 antibody
  • Bis antibody
  • CAIR-1 antibody
  • MFM6 antibody
  • mg638 antibody
  • MGC53113 antibody
  • T28J14.160 antibody
  • T28J14_160 antibody
  • zgc:100859 antibody

Protein level used designations for BAG3

BCL2-associated athanogene 3 , BAG family molecular chaperone regulator 3 , BAG family molecular chaperone regulator 3-like , BCL2-binding athanogene 3 , bcl-2-binding protein Bis , docking protein CAIR-1 , BAG-3 , Bcl-2-binding protein Bis , Bcl-2-interacting death suppressor , bcl-2-associated athanogene 3

GENE ID SPECIES
379174 Xenopus laevis
445139 Danio rerio
450778 Pan troglodytes
714420 Macaca mulatta
100145358 Xenopus (Silurana) tropicalis
100228262 Taeniopygia guttata
100481230 Ailuropoda melanoleuca
830613 Arabidopsis thaliana
9531 Homo sapiens
29810 Mus musculus
293524 Rattus norvegicus
486916 Canis lupus familiaris
782633 Bos taurus
423931 Gallus gallus
100156989 Sus scrofa
100358030 Oryctolagus cuniculus
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