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BCL2-Like 10 (Apoptosis Facilitator) Proteins (BCL2L10)

The protein encoded by BCL2L10 belongs to the BCL-2 protein family. Additionally we are shipping BCL2L10 Antibodies (55) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BCL2L10 12049 Q9Z0F3
BCL2L10 10017 Q9HD36
Rat BCL2L10 BCL2L10 114552 Q99M66
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Top BCL2L10 Proteins at

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days

BCL2L10 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

Top referenced BCL2L10 Proteins

  1. Human BCL2L10 Protein expressed in Escherichia coli (E. coli) - ABIN1098488 : Kang, Lee, Han, Yoon, Won, Yeom, Seong, Ko, Lee, Lee, Bae: NM23-H2 involves in negative regulation of Diva and Bcl2L10 in apoptosis signaling. in Biochemical and biophysical research communications 2007 (PubMed)
    Show all 2 references for ABIN1098488

More Proteins for BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10) Interaction Partners

Mouse (Murine) BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10) interaction partners

  1. Protein-protein interactions involving apoptosis regulator Diva (Boo) and the BH3 domain of proapoptotic Bcl-2 (show BCL2 Proteins) members.

  2. analysis of a novel interaction between Bcl-2 members Diva and Harakiri

  3. Structure and sequence alignment of mouse pro-survival Bcl-2 (show BCL2 Proteins) family members reveals Boo/Diva as a divergent Bcl-2 (show BCL2 Proteins) protein.

  4. The role of Bcl2l10 is strongly associated with oocyte maturation, especially at the MI-MII transition.

  5. BCL2L10 is a novel and prime candidate related to oocyte maturation, fertility, and embryo developmental competence

Human BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10) interaction partners

  1. Identification of a variant in the BCL2L10 gene as a protective factor for the development of therapy-related myeloid neoplasms and de novo myelodysplastic syndrome.

  2. polyubiquitination and proteasomal turnover dictate the expression level and anti-apoptotic capacity of Bcl-B

  3. Data suggest that BCL2L10 is localized predominantly to mitochondria in high-quality preimplantation embryos/blastocysts; in contrast, abnormal embryos/blastocysts exhibit extra-mitochondrial localization (cytoplasm/cell nucleus) of BCL2L10.

  4. Bcl-B in complex with the BH3 motif of Bim (show BCL2L11 Proteins) protected cells from Bax (show BAX Proteins)-dependent apoptotic pathways.

  5. Bcl-B interacts with the BH3 domain of BECN1 (show BECN1 Proteins) and Bcl-B overexpression reduces autophagy triggered by a variety of pro-autophagic stimuli.

  6. Ubqln stabilizes BCLb protein, while also promoting monoubiquitination on multiple lysine residues and relocation to the cytosol.

  7. BCL2L10 methylation is associated with myelodysplastic syndromes.

  8. Loss of BCL2L10 protein expression predicts poor clinical outcome in gastric carcinoma.

  9. The apoptotic gene BCL2L10 is a frequent target for aberrant promoter methylation in patients with acute leukemia, de novo and therapy-related.

  10. The pro-apoptotic effect of BCL2L10 and growth promotion by BCL2L10 siRNA in gastric cancer cells suggest that it may be a tumour suppressor.

BCL2L10 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Gene names and symbols associated with BCL2L10

  • Bcl2-like 10 (Bcl2l10)
  • BCL2-like 10 (apoptosis facilitator) (BCL2L10)
  • BCL2-like 10 (apoptosis facilitator) (Bcl2l10)
  • AA420380 protein
  • AU023065 protein
  • BCL-B protein
  • Boo protein
  • C85687 protein
  • Diva protein

Protein level used designations for BCL2L10

anti-apoptotic protein Boo , apoptosis regulator Bcl-B , bcl-2 homolog Diva , bcl-2-like protein 10 , bcl2-L-10 , anti-apoptotic protein NrH

12049 Mus musculus
10017 Homo sapiens
523056 Bos taurus
114552 Rattus norvegicus
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