BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) Proteins (BAP1)

The protein encoded by BAP1 localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). Additionally we are shipping BAP1 Antibodies (126) and BAP1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BAP1 104416 Q99PU7
BAP1 8314 Q92560
BAP1 306257 D3ZHS6
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top BAP1 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$4,123.17
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 to 8 Days
$277.20
Details

BAP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
, ,
Rat (Rattus)

More Proteins for BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) Interaction Partners

Mouse (Murine) BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) interaction partners

  1. the interaction between nephrin and MAGI-1 regulates Rap1 activation in podocytes to maintain long term slit diaphragm structure

  2. BAP1(+/-) mice exposed to low-dose asbestos fibers showed an altered peritoneal inflammatory response and higher levels of pro-tumorigenic alternatively polarized M2 macrophages, and lower cytokine levels. They had a higher incidence of mesothelioma.

  3. Bap1 loss led to a fully penetrant myeloproliferative disease with splenomegaly, leukocytosis, anemia and progenitor expansion via alterations in histone methylation and gene expression.

  4. INO80 is stabilized and targeted to replication forks by BAP1 during normal DNA synthesis but downregulated in BAP1 defective cancer cells

  5. Both Vhl (show VHL Proteins) and Bap1 are required for kidney function. Inactivation of Bap1 in neprhon progenitor cells causes renal failure earlier than Vhl (show VHL Proteins) inactivation. Bap1 is also a stronger tumor suppressor gene than Vhl (show VHL Proteins) in the kidney.

  6. Drawing parallels to human disease, these unbiased genetic findings indicate that BAP1 mutation carriers are predisposed to the tumorigenic effects of asbestos and suggest that high penetrance of mesothelioma requires such environmental exposure.

  7. Cx32 (show GJB1 Proteins) expression is in part related to induction of tight junctions through modulation of Magi1 (show CNKSR3 Proteins) expression in an immortalized hepatic cell line.

  8. ARIP1 (show MAGI2 Proteins) and ARIP2 (show SYNJ2BP Proteins) are co-expressed in some nerve cells and their biological activities are distinct.

  9. results identify a potent tumor suppressor function for BAP1 in myeloid neoplasia; propose that BAP1 forms a core complex with HCF-1 (show HCFC1 Proteins) and OGT (show OGT Proteins) that can differentially recruit additional histone-modifying enzymes to regulate gene expression and preserve norm

  10. Data conclude that the up-regulation of sdk-1 in podocytes is an important pathogenic factor in glomerulosclerosis and that the mechanism involves disruption of the actin cytoskeleton possibly via alterations in MAGI-1 (show CNKSR3 Proteins) function.

Human BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) interaction partners

  1. Loss of BAP1 (show RNF2 Proteins) expression is associated with lung adenocarcinoma.

  2. Our data confirm the established role of BAP1 as a tumor suppressor protein and is the first report where BAP1 has been studied in pT1 clear cell renal cell carcinomas

  3. Important role of BAP1 (show RNF2 Proteins) in the survival of osteosarcoma cells.

  4. Loss of BAP1 (show RNF2 Proteins) expression is a rare event in non-small cell lung cancer.

  5. BAP1 immunohistochemistry has limited prognostic utility as a complement of CDKN2A (p16) fluorescence in situ hybridization in malignant pleural mesothelioma.

  6. BAP1 (show RNF2 Proteins) and PBRM1 (show PBRM1 Proteins) loss is seen frequently in intrahepatic cholangiocarcinoma

  7. BAP1 (show RNF2 Proteins) loss and high EZH2 (show EZH2 Proteins) expression were highly specific to malignant mesothelioma in differentiating it from benign mesothelial proliferations

  8. We analyzed the prevalence of germline BAP1 (show RNF2 Proteins) mutations in a group of asbestos-exposed malignant mesothelioma patients and found non obviously pathogenic germline sequence variants of BAP1 (show RNF2 Proteins).

  9. NEAT-1 is a downstream effector of gemcitabine sensitivity in CCA (show FBN2 Proteins). The expression of BAP1 (show RNF2 Proteins) is a determinant of sensitivity to therapeutic drugs that can be exploited to enhance responses through combination strategies.

  10. lncFOXO1 suppressed the growth of breast cancer by increasing FOXO1 (show FOXO1 Proteins) transcription. Moreover, we found that lncFOXO1 associated with BRCA-1-associated protein 1 (BAP1 (show RNF2 Proteins)) and regulates its binding and the level of mono-ubiquitinated H2A at K119 (ubH2AK119) at FOXO1 (show FOXO1 Proteins) promoter

BAP1 Protein Profile

Protein Summary

The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). This gene is thought to be a tumor suppressor gene that functions in the BRCA1 growth control pathway. There are multiple polyadenylation sites found in this gene.

Gene names and symbols associated with BAP1

  • Brca1 associated protein 1 (Bap1)
  • BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (BAP1)
  • BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (Bap1)
  • BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (bap1)
  • membrane associated guanylate kinase, WW and PDZ domain containing 1 (Magi1)
  • 2300006C11Rik protein
  • AA989761 protein
  • AIP3 protein
  • AW553466 protein
  • Baiap1 protein
  • BAIAP3 protein
  • BAP1 protein
  • Gukmi1 protein
  • hucep-6 protein
  • hucep-13 protein
  • Magi-1 protein
  • MAGI1c protein
  • mKIAA0272 protein
  • mKIAA4129 protein
  • si:dkey-42i9.9 protein
  • TNRC19 protein
  • uch-x4 protein
  • uchl2 protein
  • WWP3 protein

Protein level used designations for BAP1

BRCA1-associated protein 1 , ubiquitin C-terminal hydrolase X4 , ubiquitin carboxyl-terminal hydrolase BAP1 , cerebral protein 6 , cerebral protein-13 , Brca1 associated protein 1 , BAI1-associated protein 3 , ubiquitin carboxy-terminal hydrolase , BAI1-associated protein 1 , BAP-1 , guanylate kinase membrane-associated inverted 1 , membrane-associated guanylate kinase inverted 1 , membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

GENE ID SPECIES
104416 Mus musculus
8314 Homo sapiens
484737 Canis lupus familiaris
306257 Rattus norvegicus
100124510 Bos taurus
415944 Gallus gallus
558885 Danio rerio
734438 Xenopus laevis
14924 Mus musculus
Selected quality suppliers for BAP1 Proteins (BAP1)
Did you look for something else?