Bromodomain, Testis-Specific Proteins (BRDT)

BRDT is similar to the RING3 protein family. Additionally we are shipping BRDT Antibodies (47) and BRDT Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat BRDT BRDT 305123  
BRDT 676 Q58F21
BRDT 114642 Q91Y44
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

Top BRDT Proteins at

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process IGSF3 dissolution curves 1 mg Log in to see 70 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Human His tag,DYKDDDDK Tag Recombinant BRDT (21-137) activity using AlphaScreen. BRDT (21-137) titration and inhibition were assessed using an AlphaScreen® assay. Titration curves were generated to show signal response in the presence of modified peptide substrate at increasing protein concentrations. An IC50 dose response assessment of reference compounds JQ1, I-BET151, Bromosporine and PFI-1 is also shown. This data was generated and kindly provided courtesy of ChemPartner. Recombinant BRDT (21-137) protein gel. BRDT (21-137) protein was run on a 10% SDS-PAGE gel and stained with Coomassie blue. 100 μg Log in to see 1 to 2 Days

BRDT Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

More Proteins for Bromodomain, Testis-Specific (BRDT) Interaction Partners

Human Bromodomain, Testis-Specific (BRDT) interaction partners

  1. The affected patient carries a homozygous bromodomain, testis-specific protein (show DMRT3 Proteins) (BRDT) mutation, while the patient's father, mother and elder brother all carry heterozygous BRDT mutations.

  2. considered potential associations of 14 single nucleotide polymorphisms (SNPs) in RNF8 (show RNF8 Proteins) and BRDT genes in Chinese patients with non-obstructive azoospermia

  3. assessment of rs3088232 frequency in large group of non-obstructive azoospermia men and fertile controls demonstrated no significant difference between them; conclude that testicular impairments observed were not a consequence of BRDT gene mutation

  4. In human, BRDT is the only BET gene expressed exclusively in testicular germ cells.

  5. Suggest that reduced histone methylation in the promoter of BRDT may be associated with increased transcript levels in subfertile patients.

  6. BRDT-NY gene is an alternatively spliced variant that may have an important role in the process of spermatogenesis and may be correlated with male infertility

Mouse (Murine) Bromodomain, Testis-Specific (BRDT) interaction partners

  1. Our results suggest that in addition to its critical role in the spermatogenesis process, the BRDT protein is also responsible for scheduling male puberty by regulation of the pituitary-gonad axis.

  2. It was shown that Brdt is a unique and essential regulator of male germ cell differentiation, first by driving a specific spermatogenic gene expression program and then by controling the tight packaging of the male genome.

  3. The N terminus of Brdt is involved in the recognition of Smarce1 (show SMARCE1 Proteins) as well as in the reorganization of hyperacetylated round spermatid chromatin.

  4. the first bromodomain of Brdt is critical in the formation and/or maintenance of an intact chromocenter and implicate this structure in proper remodeling of the chromatin architecture of the sperm head.

  5. phylogenetic analyses show that the BRDT germ cell-specific orthology group clearly evolves faster than its ubiquitously expressed paralogs BRD2 (show BRD2 Proteins), BRD3 (show BRD3 Proteins), and BRD4 (show BRD4 Proteins)

  6. Homozygous Brdt(Delta)(BD1 (show DEFB1 Proteins)/)(Delta)(BD1 (show DEFB1 Proteins)) mice were viable but males were sterile, producing fewer and morphologically abnormal sperm.

  7. a single bromodomain (BD1) of Brdt is responsible for selectively recognizing histone H4 tails bearing two or more acetylation marks

BRDT Protein Profile

Protein Summary

BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene.

Gene names and symbols associated with BRDT

  • bromodomain, testis-specific (Brdt)
  • bromodomain, testis-specific (brdt)
  • bromodomain, testis-specific (BRDT)
  • bromodomain containing 3 (brd3)
  • 7420412D09Rik protein
  • Brd6 protein
  • BRDT protein
  • CT9 protein
  • Fsrg3 protein
  • MGC151933 protein
  • orfx protein
  • ring3l protein

Protein level used designations for BRDT

bromodomain testis-specific protein , bromodomain, testis-specific , testis-specific bromodomain protein , bromodomain containing 3 , RING3-like protein , cancer/testis antigen 9 , bromodomain-containing female sterile homeotic-like protein , female sterile homeotic-related gene 3

305123 Rattus norvegicus
398944 Xenopus laevis
424506 Gallus gallus
469382 Pan troglodytes
479954 Canis lupus familiaris
523971 Bos taurus
733891 Xenopus (Silurana) tropicalis
100026533 Monodelphis domestica
100144959 Xenopus (Silurana) tropicalis
100586227 Nomascus leucogenys
676 Homo sapiens
114642 Mus musculus
Selected quality suppliers for BRDT Proteins (BRDT)
Did you look for something else?