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Probable pathogen-recognition receptor. Additionally we are shipping and many more products for this protein.
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The sum of the data suggests that in contrast to IgG-based immune complexes boosting immune reactivity of antigen-presenting cells, secretory IgA produced during an ongoing immune response can, in addition to its known function of immune exclusion, modulate mucosal dendritic cell conditioning via specific interaction with Dectin-1 (show CLEC7A Proteins) and SIGNR3.
the SlpA (show SEPT9 Proteins)/SIGNR3 interaction plays a key regulatory role in colitis.
study reports the macrophage response against Leishmania infantum in vivo is characterized by an M2b-like phenotype and C-type lectin receptors signature composed of Dectin-1 (show CLEC7A Proteins), mannose receptor (MR)and the DC-SIGN (show CD209 Proteins) homolog SIGNR3 expression
SIGNR3 is a new differentiation marker for myeloid mononuclear cells and indicate that some dendritic cells may be replenished by monocytes.
Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens.
CD209 antigen-like protein D
, DC-SIGN-related protein 3