C-Type Lectin Domain Family 4, Member D (CLEC4D) ELISA Kits

CLEC4D encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Additionally we are shipping CLEC4D Antibodies (66) and CLEC4D Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CLEC4D 338339 Q8WXI8
Anti-Mouse CLEC4D CLEC4D 17474 Q9Z2H6
Anti-Rat CLEC4D CLEC4D 362432 Q69FH1
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Top CLEC4D ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days

More ELISA Kits for CLEC4D Interaction Partners

Human C-Type Lectin Domain Family 4, Member D (CLEC4D) interaction partners

  1. Results show the molecular mechanism of glycolipid recognition through C-type lectin (show MBL2 ELISA Kits) receptors, which may provide clues to rational design for effective adjuvants.

  2. CLECSF8 functions as an activation receptor on myeloid cells and associates with a novel adaptor molecule

  3. Cross-linking of the receptor leads to a rapid internalization suggesting that CLECSF8 constitutes and endocytic receptor.

Mouse (Murine) C-Type Lectin Domain Family 4, Member D (CLEC4D) interaction partners

  1. activation of CLRs Dectin-2 (show CLEC6A ELISA Kits) and Dectin-3 by fungi infections triggers them for ubiquitination and degradation in a Syk (show SYK ELISA Kits)-dependent manner.

  2. The authors report that microbial stimulation triggers Mincle (Clec4e (show CLEC4E ELISA Kits)) expression through the myeloid differentiation primary response gene 88 (MyD88 (show MYD88 ELISA Kits)) pathway; a process that does not require MCL (Clecsf8, Clec4d). Conversely, they show that MCL is constitutively expressed but retained intracellularly until Mincle (show CLEC4E ELISA Kits) is induced, whereupon the receptors form heterodimers which are translocated to the cell surface.

  3. Data show that Mincle (show CLEC4E ELISA Kits), the inducible receptor for mycobacterial cord factor, is the key switch for the transition of macrophages from cytokine expression to high nitric oxide production.

  4. MCL regulates the development of vaccine-induced Th17 cells and protective immunity against lethal experimental infection with Blastomyces dermatitidis.

  5. major contributor to activation of innate immunity against M. bovis in experimental model, mirrors Mincle (show CLEC4E ELISA Kits) expression

  6. Clecsf8-/- mice exhibit higher bacterial burdens and increased mortality upon Mycobacterium tuberculosis infection.

  7. These results suggest that MCL positively regulates Mincle (show CLEC4E ELISA Kits) expression through protein-protein interaction via its stalk region, thereby magnifying Mincle (show CLEC4E ELISA Kits)-mediated signaling.

  8. Trehalose 6,6'-dimycolate-induced Mincle (show CLEC4E ELISA Kits) expression is dependent on Dectin-3-mediated NF-kappaB (show NFKB1 ELISA Kits) activation through the CARD9 (show CARD9 ELISA Kits)-BCL10 (show BCL10 ELISA Kits)-MALT1 (show MALT1 ELISA Kits) complex.

  9. Compared to their respective homodimers, Dectin-3 and Dectin-2 (show CLEC6A ELISA Kits) heterodimers bound alpha-mannans more effectively, leading to potent inflammatory responses against fungal infections.

  10. Clec4d(-/-) neutrophils did not exhibit any defect in bacterial clearance

CLEC4D Antigen Profile

Antigen Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Gene names and symbols associated with CLEC4D

  • C-type lectin domain family 4, member D (CLEC4D) antibody
  • C-type lectin domain family 4, member d (Clec4d) antibody
  • C-type lectin domain family 4, member D (Clec4d) antibody
  • CLEC-6 antibody
  • CLEC4D antibody
  • CLEC6 antibody
  • Clecsf8 antibody
  • Mcl antibody
  • Mpcl antibody

Protein level used designations for CLEC4D

C-type lectin domain family 4, member D , C-type lectin domain family 4 member D , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8 , C-type lectin receptor , C-type lectin superfamily member 8 , C-type lectin-like receptor 6 , macrophage C-type lectin , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8 , C-type lectin, superfamily member 8 , macrophage-restricted C-type lectin

473405 Pan troglodytes
611536 Canis lupus familiaris
616646 Bos taurus
338339 Homo sapiens
17474 Mus musculus
362432 Rattus norvegicus
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