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Caldesmon 1 Proteins (CALD1)

CALD1 encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. Additionally we are shipping Caldesmon Antibodies (312) and Caldesmon Kits (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CALD1 800 Q05682
Mouse CALD1 CALD1 109624  
Rat CALD1 CALD1 25687 Q62736
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Top Caldesmon Proteins at

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 9 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 16 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

CALD1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Caldesmon 1 (CALD1) Interaction Partners

Zebrafish Caldesmon 1 (CALD1) interaction partners

  1. The data provide the first functional assessment of the role of caldesmon in cardiac development in vivo, and indicate that caldesmon is essential for proper cardiac organogenesis and function.

Human Caldesmon 1 (CALD1) interaction partners

  1. ANXA1 (show ANXA1 Proteins) and CALD1 proteins are independent markers for tamoxifen therapy outcome and are associated to fast tumor progression.

  2. Data indicate that low-molecular-weight caldesmon isoforms (L-CAD) promotes migration and invasiveness of urothelial bladder carcinoma (BC) cells.

  3. Caldesmon and smoothelin (show SMTN Proteins) staining allows better delineation of the muscularis propria from the desmoplastic stromal reaction which provides a critical aide for proper staging of colonic adenocarcinomas.

  4. caldesmon is not useful in distinguishing between peritoneal epithelioid mesotheliomas and papillary serous carcinomas involving the peritoneum

  5. The data suggest that PKGIbeta enhances breast cancer cell motility and invasive capacity, at least in part, by phosphorylating CaD.

  6. Caldesmon is a possible predictor of endometrial dysregulation in patients with endometriosis.

  7. Caldesmon expression inhibits cancer cell migration and invasiveness.

  8. Disruption of the normal inhibitory function of human caldesmon 1 enhances intestinal peristalsis in both wild-type zebrafish larvae and mutant larvae that lack enteric nerves

  9. Data found phasic phosphorylation of caldesmon and ERK 1 (show MAPK3 Proteins)/2 during contractions in human myometrium.

  10. Our results show a differential behavior of h- and l-caldesmon isoforms in epithelium and stroma of colon adenocarcinoma and lymph node metastases.

Pig (Porcine) Caldesmon 1 (CALD1) interaction partners

  1. Use short interfering RNA technology to decrease the levels of the smooth muscle-specific (show EIF3K Proteins) isoform of caldesmon in intact vascular smooth muscle tissue to determine what role(s) caldesmon has in smooth muscle regulation.

Rabbit Caldesmon 1 (CALD1) interaction partners

  1. Acrylodan-labeled tropomyosin fluorescence responses to rapid myosin subfragment S1-ATP detachment in the presence of caldesmon are similar to those observed in the presence of troponin.

  2. Effect of long-term partial bladder outlet obstruction on caldesmon isoforms and their correlation with contractile function are reported.

Mouse (Murine) Caldesmon 1 (CALD1) interaction partners

  1. Silencing of Sox4 decreased not only CaD protein synthesis but also myoblast fusion in C2C12 cells and myofibril formation in mouse embryonic muscle. Overexpression of CaD in Sox4-silenced C2C12 cells rescued the differentiation process.

  2. Caldesmon-deficient mouse arterial muscles relax more slowly than wild-type tissues.

  3. distribution of the actin-binding protein (show PFN1 Proteins) caldesmon in spleen and lymph nodes of mice and rats

  4. Caldesmon binds and stabilizes actin filaments, as well as regulates actin-myosin interaction in a calcium (Ca2 (show CA2 Proteins)+)/calmodulin (CaM (show Calm2 Proteins))- and/or phosphorylation-dependent manner. (Review)

  5. K-cyclin (show PCNA Proteins) expression modulates the activity of caldesmon and through this the microfilament functions in cells

  6. This study reports a novel molecular mechanism (caldesmon), as well as a structural basis (podosomes/rosettes), to show how p53 (show TP53 Proteins) can act as an anti-motility/invasion/metastasis agent.

Caldesmon (CALD1) Protein Profile

Protein Summary

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with Caldesmon 1 Proteins (CALD1)

  • caldesmon 1 (CALD1)
  • B-cell receptor-associated protein 31 (bcap31)
  • caldesmon 1 (Cald1)
  • caldesmon-like (LOC100546285)
  • 4833423D12Rik protein
  • AI195384 protein
  • AV071549 protein
  • AW536160 protein
  • C920027I18Rik protein
  • CALD1 protein
  • caldesmon protein
  • CDM protein
  • H-CAD protein
  • HCAD protein
  • l-Cad protein
  • LCAD protein
  • NAG22 protein
  • si:bz30i22.4 protein
  • si:rp71-30i22.4 protein
  • zgc:56389 protein

Protein level used designations for Caldesmon 1 Proteins (CALD1)

caldesmon 1 , caldesmon , accessory protein BAP31 , CDM , l-caldesmon , smooth muscle caldesmon , L-caldesmon , caldesmon, smooth muscle , non-muscle caldesmon , h-caldesmon

472523 Pan troglodytes
707050 Macaca mulatta
100173490 Pongo abelii
368488 Danio rerio
800 Homo sapiens
373965 Gallus gallus
100524227 Sus scrofa
100009077 Oryctolagus cuniculus
281660 Bos taurus
109624 Mus musculus
25687 Rattus norvegicus
100546285 Meleagris gallopavo
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