anti-Caspase Recruitment Domain Family, Member 14 (CARD14) Antibodies

CARD14 encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Additionally we are shipping CARD14 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CARD14 79092 Q9BXL6
CARD14 170720 Q99KF0
CARD14 688292  
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Top anti-CARD14 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated WB Western Blot analysis of CARD14 expression in transfected 293T cell line by CARD14 MaxPab polyclonal antibody.<br><br>Lane 1: CARD14 transfected lysate(47.74 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μL Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated EIA, IHC (p)   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of CARD14 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of CARD14 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged CARD14 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IHC (p) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

CARD14 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CARD14 Antibodies

  1. Human Polyclonal CARD14 Primary Antibody for WB - ABIN528893 : Huh, Kim, Kim, Song, Jung, Jeong, Lee, Kim, Lee, An: Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer. in British journal of cancer 2013 (PubMed)

More Antibodies against CARD14 Interaction Partners

Human Caspase Recruitment Domain Family, Member 14 (CARD14) interaction partners

  1. The serine/threonine kinase (show TLK2 Antibodies) ULK2 (show ULK2 Antibodies) binds to and phosphorylates CARMA2sh.

  2. MALT1 (show MALT1 Antibodies) deficiency or pharmacological inhibition of MALT1 (show MALT1 Antibodies) catalytic activity inhibits pathogenic mutant CARD14-induced cytokine and chemokine (show CCL1 Antibodies) expression in human primary keratinocytes.

  3. CARD14/MALT1 (show MALT1 Antibodies)-mediated signaling in keratinocytes has a role in psoriasis [review]

  4. The results indicate that the common CARD14 p.Arg820Trp variant might have a significant effect on the response to anti-TNF (show TNF Antibodies) therapies among patients with psoriasis. In addition, rare CARD14 missense variants could also predispose to a better response.

  5. Our findings, combined with the published literature, suggest that Pityriasis Rubra Pilaris Type V, both familial and sporadic, can be caused by CARD14 mutations.

  6. Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10 (show BCL10 Antibodies)-MALT1 (show MALT1 Antibodies)-dependent NF-kappaB (show NFKB1 Antibodies) activation

  7. genetic evidence suggests association of the CARD14 single nucleotide polymorphism rs11652075 and other rare mutations in this gene with psoriasis. To assess whether combined data support the relationship between CARD14 rs11652075 and susceptibility to this disease, we conducted a meta-analysis. Our results demonstrate a significant association between the CARD14 rs11652075 polymorphism and psoriasis.

  8. The authors observations provide further insights into the genetics of psoriasis and functional information on novel CARD14 mutational variants seen in cases from Tunisia and other populations.

  9. Genetic interactions of SNPs in CARD14, SENP1 (show SENP1 Antibodies) and VEGFA (show VEGFA Antibodies) might represent a functional mechanism in the pathogenesis of high altitude polycythemia.

  10. analysis of 105 individuals with generalized pustular psoriasis (GPP) identified a low-frequency variant (p.Asp176His) that causes constitutive CARD14 oligomerization

CARD14 Antigen Profile

Protein Summary

This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with CARD14

  • caspase recruitment domain family member 14 (CARD14) antibody
  • caspase recruitment domain family, member 14 (Card14) antibody
  • Bimp2 antibody
  • CARMA2 antibody
  • PRP antibody
  • PSORS2 antibody
  • PSS1 antibody

Protein level used designations for CARD14

CARD-containing MAGUK protein 2 , bcl10-interacting maguk protein 2 , card-maguk protein 2 , carma 2 , caspase recruitment domain-containing protein 14 , bcl10-interacting MAGUK protein 2

GENE ID SPECIES
79092 Homo sapiens
170720 Mus musculus
688292 Rattus norvegicus
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