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CDC25B is a member of the CDC25 family of phosphatases. antibodies-online currently ships Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) Antibodies (188), and to destinations worldwide.
Show Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) Antigene Profile
Showing 6 out of 9 Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) ELISA Kits
RSK (show RPS6KA1 ELISA Kits) promotes G2/M transition in mammalian cells through activating phosphorylation of Cdc25A (show CDC25A ELISA Kits) and Cdc25B.
Cdc25B upregulation and 14-3-3sigma downregulation might promote development of bladder cancer and suggested a poor prognosis.
Positive expression of CDC25B in astrocytoma affects the prognosis in an adverse manner.
CDC25B is a pro-influenza A virus host factor.
CDC25B, through activation of a centrosomal pool of CDK2 (show CDK2 ELISA Kits), stabilises the local pool of Mps1 (show IDUA ELISA Kits) which in turn regulates the level of centrin 2 (show CETN2 ELISA Kits) at the centrosome.
Phosphorylation and inhibition of cdc25B causes delayed progression from G2 into mitosis in melanoma cells.
Indirubin, an acting component of indigo naturalis, inhibits EGFR (show EGFR ELISA Kits) activation and EGF (show EGF ELISA Kits)-induced CDC25B gene expression in epidermal ke
downregulation of Cdc25B resulted in slower growth, more G2/M cells, weaker capacity for migration and invasion and induction of apoptosis in renal carcinoma cell line 769-P transfectants; findings suggest an important role of Cdc25B in renal cell carcinoma development
Transcriptional repression mediated by IER5 (show IER5 ELISA Kits) regulates Cdc25B expression levels via the release of NF-YB (show NFYB ELISA Kits) and p300 (show EP300 ELISA Kits) in acute myeloid leukemia (show BCL11A ELISA Kits).
We identified CDC25B as novel miR (show MLXIP ELISA Kits)-148a target which may confer a proliferative advantage in pancreatic ductal adenocarcinomas.
Ser321 of Cdc25B is the specific binding site for 14-3-3epsilon (show YWHAE ELISA Kits) binding.
Protein kinase (show MOS ELISA Kits) A the early development of mouse embryos by phosphorylation of S149 and S321 of CDC25B, which plays an important role in the regulation of G(2)/M transition in the mitotic cell cycle of fertilized mouse eggs.
In the DNA damage response, instead of inhibiting cyclin B (show CCNB1 ELISA Kits)-CDK1 (show CDK1 ELISA Kits) through destruction of Cdc25A (show CDC25A ELISA Kits) phosphatase, oocytes utilize an inhibitory phosphorylation of Cdc25B.
Cdc25B overexpression in early mouse two-cell embryos reverses two-cell block and promotes their development into four-cell stage by activating MPF (show MSLN ELISA Kits).
MCPH1 (show MCPH1 ELISA Kits), through its function in the Chk1 (show CHEK1 ELISA Kits)-Cdc25 (show CDC25C ELISA Kits)-Cdk1 (show CDK1 ELISA Kits) pathway to couple the centrosome cycle with mitosis, is required for precise mitotic spindle orientation and thereby regulates the progenitor division mode to maintain brain size.
CDC25A (show CDC25A ELISA Kits) and CDC25B but not CDC25C (show CDC25C ELISA Kits) compensate for each other to maintain the proliferative capacity of intestinal epithelial stem and progenitor cells
Ser (show SIGLEC1 ELISA Kits)(149) may be another potential PKA phosphorylation target of Cdc25B in G(2)/M transition of fertilized mouse eggs and Cdc25B as a direct downstream substrate of PKA in mammals
Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation
Cdc25A (show CDC25A ELISA Kits), or possibly other phosphatases, is able to functionally compensate for the loss of Cdc25B and Cdc25C (show CDC25C ELISA Kits) in mice
Shh (show SHH ELISA Kits) contributes to CDC25B transcriptional activation in the neural tube both of chick and mouse embryos
cell division cycle 25B (cdc25b)
, cell division cycle 25 homolog B (S. pombe) (CDC25B)
, cell division cycle 25B (CDC25B)
, cell division cycle 25B (Cdc25b)
cell division cycle 25 homolog B
, cell division cycle 25 homolog B (S. pombe)
, M-phase inducer phosphatase 2-like
, m-phase inducer phosphatase 2-like
, cell division cycle 25B
, M-phase inducer phosphatase 2
, dual specificity phosphatase Cdc25B
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.