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Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) ELISA Kit Abstract

CDC25B is a member of the CDC25 family of phosphatases. antibodies-online currently ships Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) Antibodies (155), and to destinations worldwide.

list all ELISA KIts Gene Name GeneID UniProt
CDC25B 994 P30305
CDC25B 12531 P30306
CDC25B 171103 P48966

Show Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) Antigene Profile

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Top Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) ELISA Kits at antibodies-online.com

Showing 6 out of 9 Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) ELISA Kits

ABIN Reactivity Sensitivity Range Quantity Delivery Validation Price Details
ABIN812244 Human 9.75 pg/mL 39.06-2500 pg/mL 96 Tests 11 to 13 days Data Validation Level 4/5
910.56 $
Details
ABIN812246 Rat n/a n/a 96 Tests 11 to 13 days Data Validation Level 4/5
910.56 $
Details
ABIN812245 Mouse n/a n/a 96 Tests 11 to 13 days Data Validation Level 4/5
910.56 $
Details
ABIN1380112 Human n/a n/a 96 Tests 21 to 31 days Data Validation Level 3/5
450.00 $
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ABIN1380386 Human n/a n/a 96 Tests 21 to 31 days Data Validation Level 3/5
450.00 $
Details
ABIN1381007 n/a n/a 96 Tests 2 to 3 days Data Validation Level 1/5
350.00 $
Details

CDC25B ELISA Kits by Sample Type and Reactivity

Attributes Samples
Human , , ,

More ELISA Kits for Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) Interaction Partners

Human Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) interaction partners

  1. Indirubin, an acting component of indigo naturalis, inhibits EGFR activation and EGF-induced CDC25B gene expression in epidermal ke

  2. downregulation of Cdc25B resulted in slower growth, more G2/M cells, weaker capacity for migration and invasion and induction of apoptosis in renal carcinoma cell line 769-P transfectants; findings suggest an important role of Cdc25B in renal cell carcinoma development

  3. Transcriptional repression mediated by IER5 regulates Cdc25B expression levels via the release of NF-YB and p300 (show EP300 ELISA Kits) in acute myeloid leukemia.

  4. We identified CDC25B as novel miR-148a target which may confer a proliferative advantage in pancreatic ductal adenocarcinomas.

  5. Ser169 phosphorylation can disrupt 14-3-3 binding to Ser151 activating Cdc25B3, providing a mechanism for regulating Cdc25B3 activation without dephosphorylation of the 14-3-3 binding sites.

  6. there are 13 sites phosphorylated by PLK1 in CDC25B.This study illustrates the complexity of the phosphorylation pattern and of the subsequent regulation of CDC25B activity.

  7. Deletion and mutation analyses of the Cdc25B promoter revealed that downregulation by p53 is dependent on the presence of functional Sp1/Sp3 and NF-Y binding sites

  8. CDC25B forms a close association with Ctn-2 proteins at the centrosome.

  9. Our findings reveal the existence of a previously unrecognized CDC25B isoform that operates specifically in the nucleus to reinitiate G2/M transition after DNA damage

  10. Cdc14A phosphatase prevents premature activation of Cdk1 regulating Cdc25A and Cdc25B at the entry into mitosis.

Mouse (Murine) Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) interaction partners

  1. Ser321 of Cdc25B is the specific binding site for 14-3-3epsilon binding.

  2. Protein kinase A the early development of mouse embryos by phosphorylation of S149 and S321 of CDC25B, which plays an important role in the regulation of G(2)/M transition in the mitotic cell cycle of fertilized mouse eggs.

  3. In the DNA damage response, instead of inhibiting cyclin B-CDK1 through destruction of Cdc25A phosphatase, oocytes utilize an inhibitory phosphorylation of Cdc25B.

  4. Cdc25B overexpression in early mouse two-cell embryos reverses two-cell block and promotes their development into four-cell stage by activating MPF.

  5. MCPH1, through its function in the Chk1-Cdc25-Cdk1 pathway to couple the centrosome cycle with mitosis, is required for precise mitotic spindle orientation and thereby regulates the progenitor division mode to maintain brain size.

  6. CDC25A and CDC25B but not CDC25C compensate for each other to maintain the proliferative capacity of intestinal epithelial stem and progenitor cells

  7. Ser(149) may be another potential PKA phosphorylation target of Cdc25B in G(2)/M transition of fertilized mouse eggs and Cdc25B as a direct downstream substrate of PKA in mammals

  8. Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation

  9. Cdc25A, or possibly other phosphatases, is able to functionally compensate for the loss of Cdc25B and Cdc25C in mice

  10. Shh contributes to CDC25B transcriptional activation in the neural tube both of chick and mouse embryos

Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B) Antigene Profile

Gene names and symbols associated with CDC25B

cell division cycle 25 homolog B (S. pombe) (CDC25B) , cell division cycle 25B (CDC25B) , cell division cycle 25B (Cdc25b) , cell division cycle 25B (cdc25b)

AI604853 , CDC25B

Protein level used designations for CDC25B

M-phase inducer phosphatase 2 , dual specificity phosphatase Cdc25B , cell division cycle 25 homolog B , cell division cycle 25 homolog B (S. pombe) , M-phase inducer phosphatase 2-like , m-phase inducer phosphatase 2-like , cell division cycle 25B

Antigene Summary

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.

GENE ID SPECIES
485790 Canis lupus familiaris
505847 Bos taurus
100329127 Sus scrofa
994 Homo sapiens
12531 Mus musculus
171103 Rattus norvegicus
100036608 Xenopus (Silurana) tropicalis
100052425 Equus caballus
100395201 Callithrix jacchus
100434256 Pongo abelii
100483177 Ailuropoda melanoleuca
458064 Pan troglodytes
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