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Centrosomal Protein 120kDa (CEP120) ELISA Kits

CEP120 encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. Additionally we are shipping CEP120 Antibodies (18) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CEP120 225523 Q7TSG1
CEP120 153241 Q8N960
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More ELISA Kits for CEP120 Interaction Partners

Mouse (Murine) Centrosomal Protein 120kDa (CEP120) interaction partners

  1. The loss of Talpid3-binding centrosomal protein Cep120 results in failed centriole duplication and consequently ciliogenesis, which together underlie Cep120 mutant cerebellar hypoplasia.

  2. Cep120 is required for centriole assembly and that the observed defect in neuronal migration might derive from a defect in this process.

Human Centrosomal Protein 120kDa (CEP120) interaction partners

  1. We establish a novel locus for Jeune asphyxiating thoracic dystrophy on 5q23.2 by linkage analysis and demonstrate that a mutation in CEP120 within this locus is the most likely cause of the disease.

  2. CEP120 associates with SPICE1 (show SPICE1 ELISA Kits) and CPAP (show CENPJ ELISA Kits), and depletion of any of these proteins results in short procentrioles. Furthermore, CEP120 or CPAP (show CENPJ ELISA Kits) overexpression results in excessive centriole elongation, a process dependent on CEP120, SPICE1 (show SPICE1 ELISA Kits), and CPAP (show CENPJ ELISA Kits).

  3. CEP120 is a CPAP (show CENPJ ELISA Kits)-interacting protein that positively regulates centriole elongation.

CEP120 Antigen Profile

Antigen Summary

This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with CEP120

  • centrosomal protein 120 (Cep120) antibody
  • centrosomal protein 120kDa (CEP120) antibody
  • centrosomal protein 120kDa (Cep120) antibody
  • A230075C01 antibody
  • AU016693 antibody
  • CCDC100 antibody

Protein level used designations for CEP120

centrosomal protein of 120 kDa , coiled-coil domain containing 100 , coiled-coil domain-containing protein 100

225523 Mus musculus
153241 Homo sapiens
534400 Bos taurus
100718525 Cavia porcellus
101110325 Ovis aries
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