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Chemokine (C-C Motif) Receptor 7 Proteins (CCR7)

The protein encoded by CCR7 is a member of the G protein-coupled receptor family. Additionally we are shipping CCR7 Antibodies (274) and CCR7 Kits (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCR7 12775 P47774
CCR7 1236 P32248
CCR7 287673  
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Top CCR7 Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

CCR7 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , , ,

Rat (Rattus)

More Proteins for Chemokine (C-C Motif) Receptor 7 (CCR7) Interaction Partners

Zebrafish Chemokine (C-C Motif) Receptor 7 (CCR7) interaction partners

  1. Ccr7 functions during axis formation as a GPCR to inhibit beta-catenin (show CTNNB1 Proteins), likely by promoting Ca(2 (show CA2 Proteins)+) transients throughout the blastula.

Mouse (Murine) Chemokine (C-C Motif) Receptor 7 (CCR7) interaction partners

  1. This study reveals a role for CCR7 in limiting Treg recirculation back to the thymus and enables separation of the mechanisms controlling Treg production and thymic recirculation.

  2. data reveal that CCR7 plays multifaceted roles in regulating collecting vessel permeability and fibrosis, with one of the key players being IRF4 (show IRF4 Proteins)-dependent DCs.

  3. the graft site microenvironment plays a critical role in alloimmunity by determining DC trafficking through the CCR7-CCL19 (show CCL19 Proteins)/21 axis.

  4. Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta (show CD247 Proteins)) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice

  5. CD11b (show ITGAM Proteins) and CXCR4 (show CXCR4 Proteins) but not CCR7 have roles in neutrophil migration modulating lymph node lymphocyte proliferation in bacterial infections

  6. The results highlight a novel role of CCR7 in regulating effector CD8 (show CD8A Proteins) T cell migration in the spleen and demonstrate differential requirement of CCR7 for primary and secondary CD8 (show CD8A Proteins) T cell responses to infection.

  7. mucosal draining lymph nodes express CCR7, which has a role in trafficking of RORgamma innate lymphoid cells

  8. results demonstrate a contribution of CCR7 to STAP-2 (show STAP2 Proteins)-dependent enhancement of BCR-ABL (show ABL1 Proteins)-mediated cell growth in Ba/F3 cells

  9. CCR7 increases the secretion of nitric oxide and modulates the T cell immune response.

  10. Results suggest that Mfn2 (show MFN2 Proteins) and OPA1 are upregulated during bone marrow progenitor differentiation and promote the migration of immature dendritic cells by regulating the expression of CCR7.

Human Chemokine (C-C Motif) Receptor 7 (CCR7) interaction partners

  1. Constitutively expressed Siglec-9 (show SIGLEC9 Proteins) inhibits LPS (show IRF6 Proteins)-induced CCR7, but enhances IL-4 (show IL4 Proteins)-induced CD200R (show CD200R1 Proteins) expression in human macrophages.

  2. High CXCR4 (show CXCR4 Proteins) expression in primary breast tumors (PTs (show PTS Proteins)) was found to be associated with luminal A type tumor, suggesting more favorable outcome. In contrast, CCR7 and FOXP3 (show FOXP3 Proteins) expressions in PTs (show PTS Proteins) represented luminal B tumors, pointing to more aggressive tumor behavior. Maspin (show SERPINB5 Proteins) expression did not differ between luminal types.

  3. Results indicated that CCR7 is overexpressed in gallbladder cancer tissues and its expression correlates with staging and lymph node metastasis.

  4. CCL21 (show CCL21 Proteins)/CCR7 induce VEGF-D (show Figf Proteins) up-regulation and promote lymphangiogenesis via ERK (show EPHB2 Proteins)/Akt (show AKT1 Proteins) pathway in lung cancer.

  5. The present study demonstrated that down-regulation of CCR7 reduced proliferation, cell cycle, cell migration and invasion in prostate cancer cells

  6. Our findings suggested that MUC1 (show MUC1 Proteins) plays an important role in CCL21 (show CCL21 Proteins)-CCR7-induced lymphatic metastasis and may serve as a therapeutic target in esophageal squamous cell carcinoma .

  7. Membrane associated PGES1dependent release of PGE2 is ccompanied by elevated CCR7 expression in colon cancer cells.

  8. Pyk2 (show PTK2B Proteins) is a key downstream signaling molecules of CCR7 in SCCHN, which promotes SCCHN tumorigenesis and progression.

  9. the CCR7 axis mediates TGF-beta1 (show TGFB1 Proteins)-induced EMT (show ITK Proteins) via crosstalk with NF-kappaB (show NFKB1 Proteins) signaling, facilitating lymph node metastasis and poorer overall survival in patients with gastric cancer

  10. Blockade of CCR7, or treatment with a p38 MAP kinase (show MAPK14 Proteins) inhibitor, reduced lymphatic dissemination of epithelial-mesenchymal transition cells.

Cow (Bovine) Chemokine (C-C Motif) Receptor 7 (CCR7) interaction partners

  1. Fluorescent dye-labeled gammadelta T cells from afferent and efferent lymph lack CCR7 surface expression and display high levels of CD62L (show SELL Proteins) compared with CD4 (show CD4 Proteins) T cells, which do express CCR7.

  2. CCR7 transcripts were minimally expressed in ex vivo and proliferating WC1(+)gammadelta T cells, a unique cell population with proinflammatory characteristics

Pig (Porcine) Chemokine (C-C Motif) Receptor 7 (CCR7) interaction partners

  1. the pattern of expression of CCR7 in different populations of porcine lymphocytes appears to be similar to that of human, highlighting the value of the pig as a useful animal model for biomedical studies.

  2. Pre-translntation of sertli cell CCR7 significantly suppresses lymphocyte proliferation and prolongs allogeneic skin graft survival.

CCR7 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.

Gene names and symbols associated with CCR7

  • chemokine (C-C motif) receptor 7 (ccr7)
  • chemokine (C-C motif) receptor 7 (CCR7)
  • chemokine (C-C motif) receptor 7 (LOC100338432)
  • chemokine (C-C motif) receptor 7 (Ccr7)
  • BLR2 protein
  • ccr7-a protein
  • CD197 protein
  • CDw197 protein
  • CMKBR7 protein
  • EBI1 protein
  • Ebi1h protein
  • zgc:165629 protein

Protein level used designations for CCR7

C-C chemokine receptor type 7 , zfCCR7 , CC chemokine receptor 7 , chemokine (C-C motif) receptor 7 a , chemokine (C-C motif) receptor 7 , c-C chemokine receptor type 7-like , C-C CKR-7 , CC-CKR-7 , CCR-7 , EBV-induced G-protein coupled receptor 1 , MIP-3 beta receptor , chemokine (C-C) receptor 7 , epstein-Barr virus-induced G-protein coupled receptor 1 , EBV-induced G protein-coupled receptor 1 , Epstein-Barr virus induced G-protein coupled receptor , Epstein-Barr virus induced gene 1 , lymphocyte-specific G protein-coupled peptide receptor , chemokine receptor 7

565958 Danio rerio
574231 Macaca mulatta
100036961 Xenopus laevis
100338432 Oryctolagus cuniculus
100432347 Pongo abelii
12775 Mus musculus
1236 Homo sapiens
287673 Rattus norvegicus
510668 Bos taurus
491011 Canis lupus familiaris
428315 Gallus gallus
100728690 Cavia porcellus
396663 Sus scrofa
101109462 Ovis aries
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