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CXCR5 encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. Additionally we are shipping CXCR5 Antibodies (226) and CXCR5 Kits (12) and many more products for this protein.
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identified the miR (show MLXIP Proteins)-19a/CXCR5 pathway as a candidate p53 (show TP53 Proteins)-induced migration mechanism
CXCL13 (show CXCL13 Proteins)/CXCR5 mediated the aggregation of B cells, that directed the aberrant humoral immune responses via the formation of ectopic germinal centers, which suggests a molecular mechanism of neurological damage in neurosyphilis.
the data demonstrate that CXCR5(+)CD8 (show CD8A Proteins)(+) T cells represent a significant CD8 (show CD8A Proteins)(+) T cell subset in colorectal tumors and have the potential to contribute to antitumor immunity, but their specific roles require further studies in vivo.
we demonstrate that PKCepsilon (show PRKCE Proteins) cooperates with the loss of the tumor suppressor Pten for the development of prostate cancer in a mouse model. Mechanistic analysis revealed that PKCe (show PRKCE Proteins) overexpression and Pten loss individually and synergistically upregulate the production of the chemokine (show CCL1 Proteins) CXCL13 (show CXCL13 Proteins), which involves the transcriptional activation of the CXCL13 (show CXCL13 Proteins) gene
Levels of CXCR5 mRNA and protein levels were up-regulated in brain from temporal lobe epilepsy patients.
Neoplastic cells of PCSM-TCL (show RHOJ Proteins) are medium- to-large-sized T cells with cerebriform nuclei, which lack the expression of TFH-cell defining chemokine receptor CXCR5. These features are highly distinctive and can be invaluable in separating this rather indolent cutaneous T-cell lymphoid neoplasm from more aggressive lymphomas of TFH-cell phenotype, including primary cutaneous TFH-cell lymphoma and skin involvement of AITL
CXCR5 expression positively related to the lymph node and distal metastasis, tumor stage and relapse of colorectal cancer.
In patients with HBV-related hepatocellular carcinoma the phenotype and function of CXCR5+CD45RA-CD4 (show CD4 Proteins)+ T cells were altered.
HCV infection increased the frequency of CD4 (show CD4 Proteins)+CXCR5+ T cells and decreased the frequency of CD27 (show CD27 Proteins)+IgG+ B cells. CD4 (show CD4 Proteins)+CXCR5+ T cells activated CD27 (show CD27 Proteins)+IgG+ B cells via the secretion of IL-21 (show IL17C Proteins).
Authors demonstrate that CD40 (show CD40 Proteins) expression upregulates the chemokine receptor CXCR5 and promotes MDSC migration toward and accumulation within cancer.
CXCL13 (show CXCL13 Proteins) and CXCR5 contribute to orofacial pain via ERK (show EPHB2 Proteins)-mediated proinflammatory cytokines production.
Cxcr5 role in the protection of retinal pigment epithelium and retinal cells during aging and Cxcr5 loss may lead to age-related macular degeneration like pathological changes in aged mice.
These data suggest that CXCR5-expressing conventional dendritic cells play an important role in the efficient propagation of orally administered prions toward follicular dendritic cells within Peyer's patches in order to establish host infection.
CXCR5 is involved critically in B cell trafficking and germinal cell formation in murine lupus and in guiding pathogenic double-negative T cells into lymphoid organs and kidneys.
The importance of CXCR5 in autoimmune arthritis varies depending on environmental circumstances.
findings reveal a neuronal/astrocytic interaction in the spinal cord by which neuronally produced CXCL13 (show CXCL13 Proteins) activates astrocytes via CXCR5 to facilitate neuropathic pain.
IL-33 (show IL33 Proteins) enhances humoral immunity against chronic hbv infection through activating CD4 (show CD4 Proteins)(+)CXCR5(+) helper-Inducer T-Lymphocytes.
Results identify p66Shc (show SHC1 Proteins) as a negative regulator of B-cell chemotaxis and suggest a role for this adaptor in the control of B-cell homing via CXCR4 (show CXCR4 Proteins)/5.
The results of this study suggested that CXCR5 may impair the maintenance of hippocampal neuroblast and neuronal precursor cell populations, while increasing the proliferation of (Ki67 (show MKI67 Proteins) positive) cells in the subgranular zone of the dentage gyrus.
Interruption of CXCL13 (show CXCL13 Proteins)-CXCR5 axis increases upper genital tract pathology and activation of NKT (show CTSL1 Proteins) cells following chlamydial genital infection.
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)
, C-X-C chemokine receptor type 5
, chemokine receptor
, Burkitt lymphoma receptor 1
, chemokine (C-X-C motif) receptor 5
, c-X-C chemokine receptor type 5-like
, Burkitt lymphoma receptor 1, GTP-binding protein
, monocyte-derived receptor 15
, burkitt lymphoma receptor 1 homolog
, chemochine (C-X-C motif) receptor 5
, neurolymphatic receptor