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Chibby Homolog 1 (Drosophila) (CBY1) ELISA Kits

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. Additionally we are shipping CBY1 Antibodies (34) and CBY1 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CBY1 25776 Q9Y3M2
CBY1 73739 Q9D1C2
CBY1 246768 Q8K4I6
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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
96 Tests Log in to see 11 to 13 Days
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96 Tests Log in to see 11 to 13 Days
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More ELISA Kits for CBY1 Interaction Partners

Xenopus laevis Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression.

Human Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. Cby's C-terminal domain alone binds to TC-1 (show SLC19A2 ELISA Kits) with significantly greater affinity compared to full-length Cby, implying that target binding of the coiled-coil domain is affected by the flanking disordered regions.

  2. CBY1 downregulation in CML (show BCR ELISA Kits) comes from reduced protein stability when bound to 14-3-3sigma adapter protein (show TOLLIP ELISA Kits). Dissociation raises CBY1 protein levels by enhancing its stability. The ubiquitin proteasome system reduces 14-3-3sigma-bound CBY1 stability by SUMOylation.

  3. Results show the hypermethylation of CBY1 and BCL2 (show BCL2 ELISA Kits)-like11 promoters proceeding from DNMT1 (show DNMT1 ELISA Kits) is a crucial component of their reduced expression, but it is not directly involved in chronic myeloid leukemia (show BCL11A ELISA Kits) resistance to imatinib.

  4. Study showed that expression of Cby protein was strongly downregulated in laryngeal squamous cell carcinoma (LSCC) tumor tissues in comparison to normal laryngeal mucosa samples.

  5. the impact of BCR (show BCR ELISA Kits)-ABL1 (show ABL1 ELISA Kits) on Chibby1, a beta (show SUCLA2 ELISA Kits) catenin (show CTNNB1 ELISA Kits) antagonist involved in cell differentiation and transformation

  6. Stable expression of CBY1 drives beta catenin (show CTNNB1 ELISA Kits) cytoplasmatic translocation and impairs beta catenin (show CTNNB1 ELISA Kits) signaling in BCR-ABL (show ABL1 ELISA Kits) + cells.

  7. Results from the association analysis suggest that common variation in CBY is not a cause for obesity in the Belgian population.

  8. C-terminal polycystin-2 (show PKD2 ELISA Kits) influences the interaction with PIGEA14

  9. Cby plays an important role in organization of both primary and motile cilia in collaboration with Cnx (show CANX ELISA Kits).

  10. The N-terminal portion of the CBY1 is unstructured in solution, but the C-terminal half forms a coiled-coil structure.

Mouse (Murine) Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. Cby1 is required for efficient recruitment of Ahi1 (show AHI1 ELISA Kits), providing a possible molecular mechanism for the ciliogenesis defect in Cby1(-/-) cells.

CBY1 Antigen Profile

Antigen Summary

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CBY1

  • chibby homolog 1 (cby1) antibody
  • chibby homolog 1 (Drosophila) (CBY1) antibody
  • chibby homolog 1 (Drosophila) (Cby1) antibody
  • 1110014P06Rik antibody
  • arb1 antibody
  • C22orf2 antibody
  • CBY antibody
  • chibby antibody
  • HS508I15A antibody
  • Pgea1 antibody
  • PGEA14 antibody
  • PIGEA-14 antibody
  • PIGEA14 antibody

Protein level used designations for CBY1

chibby homolog 1 , leucine-rich protein , ARPP-binding protein , PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 , PKD2 interactor, golgi and endoplasmic reticulum associated 1 , coiled-coil protein PIGEA-14 , cytosolic leucine-rich protein , polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa , protein chibby homolog 1 , PIGEA-14

398327 Xenopus laevis
549007 Xenopus (Silurana) tropicalis
25776 Homo sapiens
73739 Mus musculus
246768 Rattus norvegicus
282859 Bos taurus
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