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Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. Additionally we are shipping CETP Antibodies (120) and CETP Kits (58) and many more products for this protein.
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The rs1800775, rs3764261, rs12149545, rs711752, and rs708272 polymorphisms of CETP were associated with metabolic syndrome and its components among the Uyghur ethnic group. Complete linkage disequilibrium was found between two pairs of SNPs (rs3764261 and rs12149545, rs711752, and rs708272).
CETP-inhibition, although effective in improving the lipid profile, is not associated with vascular protective effects as assessed by endothelial function.
The study identified two polymorphisms with a higher risk of age-related macular degeneration development (AMD (show AMD1 Proteins)) and also a protective polymorphism for AMD (show AMD1 Proteins).
CETP TaqIB polymorphism protects against composite ischemic CVD risk and is associated with a higher HDL (show HSD11B1 Proteins)-C concentration in both Asians and Caucasians (Meta-Analysis)
Combined exposure to variants in the genes that encode the targets of CETP inhibitors and statins was associated with discordant reductions in LDL-C and apoB (show APOB Proteins) levels and a corresponding risk of cardiovascular events that was proportional to the attenuated reduction in apoB (show APOB Proteins) but significantly less than expected per unit change in LDL-C.
Treatment of mildly hypercholesterolemic subjects with CETP inhibitor anacetrapib reduces Lp(a (show APOA Proteins)) levels by decreasing its production.
Carriers of protein-truncating variants of CETP displayed higher high-density lipoprotein cholesterol and lower risk for coronary heart disease.
Based on results from the study with a relatively large sample size, CETP may be the only detectable locus with common genetic variants that influence HDL (show HSD11B1 Proteins)-C response to statins substantially in individuals of European descent. Although CETP is known to be associated with HDL (show HSD11B1 Proteins)-C, the evidence is provided that this pharmacogenetic effect is independent of its association with baseline HDL (show HSD11B1 Proteins)-C levels.
The rs1800775 [1.31 (1.22-1.42); p = 3.41E-12] in the CETP gene and rs359027 [1.26 (1.16-1.36); p = 2.55E-08] in the LMCD1 (show LMCD1 Proteins) gene were significantly associated with LHDLC levels
CETP modulates the distribution of spingosine-1-phosphate among lipoproteins, which affects the bioactivities of S1P (show MBTPS1 Proteins).
Genetic ablation of CETP activity protects against cholesterol diet-induced atherosclerosis in rabbits.
Cholesteryl ester transfer protein is the sole major determinant of cholesteryl ester transfer in normolipidemic rabbit plasma as a result of the inability of rabbit apoCI to change HDL (show HSD11B1 Proteins) electronegativity.
Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. CETP may effect susceptibility to atherosclerosis.
BPI fold containing family F
, cholesteryl ester transfer protein
, lipid transfer protein I
, Lipid transfer protein I