Cirrhosis, Autosomal Recessive 1A (Cirhin) Proteins (CIRH1A)

CIRH1A encodes a WD40-repeat-containing protein that is localized to the nucleolus. Additionally we are shipping CIRH1A Antibodies (33) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CIRH1A CIRH1A 291987  
CIRH1A 84916 Q969X6
Mouse CIRH1A CIRH1A 21771 Q8R2N2
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Top CIRH1A Proteins at

Showing 3 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days

CIRH1A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Cirrhosis, Autosomal Recessive 1A (Cirhin) (CIRH1A) Interaction Partners

Zebrafish Cirrhosis, Autosomal Recessive 1A (Cirhin) (CIRH1A) interaction partners

  1. data provide the first in vivo evidence of a role for Cirhin in biliary development, and support the hypothesis that congenital defects affecting ribosome biogenesis can activate a cellular stress response mediated by p53 (show TP53 Proteins)

Human Cirrhosis, Autosomal Recessive 1A (Cirhin) (CIRH1A) interaction partners

  1. Results show that CIRH1A was highly expressed in carcinoma samples and colorectal cancer cells and suggest that CIRH1A plays a critical role in the proliferation, cell cycle distribution, and apoptosis of human malignant colorectal cells.

  2. A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis

  3. Cirhin is a nucleolar protein (show MCRS1 Proteins) and the R565W mutation, for which all North American Indian childhood cirrhosis patients are homozygous, has no effect on subcellular localization.

  4. Cirhin is a transcriptional regulatory factor of this NF-kappaB (show NFKB1 Proteins) sequence and could be a participant in the regulation of other genes with NF-kappaB (show NFKB1 Proteins) responsive elements.

CIRH1A Protein Profile

Protein Summary

This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence.

Gene names and symbols associated with CIRH1A

  • cirrhosis, autosomal recessive 1A (cirhin) (CIRH1A)
  • cirrhosis, autosomal recessive 1A (cirhin) (Cirh1a)
  • cirrhosis, autosomal recessive 1A (cirhin) (cirh1a)
  • cirrhosis, autosomal recessive 1A (human) (Cirh1a)
  • CIRH1A protein
  • CIRHIN protein
  • NAIC protein
  • Teg-292 protein
  • TEX292 protein
  • UTP4 protein
  • wu:fi09g10 protein
  • wu:fi37c02 protein
  • zgc:77199 protein

Protein level used designations for CIRH1A

cirhin , testis-expressed gene 292 , cirrhosis, autosomal recessive 1A (cirhin) , cirhin-like , UTP4, small subunit (SSU) processome component, homolog , testis expressed gene 292 , testis-expressed gene 292 protein

454197 Pan troglodytes
510315 Bos taurus
291987 Rattus norvegicus
733991 Xenopus (Silurana) tropicalis
406571 Danio rerio
100172915 Pongo abelii
769632 Gallus gallus
489738 Canis lupus familiaris
379136 Xenopus laevis
100066965 Equus caballus
100401215 Callithrix jacchus
100474816 Ailuropoda melanoleuca
100020058 Monodelphis domestica
100547335 Meleagris gallopavo
100597751 Nomascus leucogenys
84916 Homo sapiens
21771 Mus musculus
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