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Collagen, Type II, alpha 1 (COL2A1) ELISA Kits

COL2A1 encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Additionally we are shipping COL2A1 Antibodies (89) and COL2A1 Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
COL2A1 12824 P28481
COL2A1 1280 P02458
COL2A1 25412 P05539
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Top COL2A1 ELISA Kits at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Rat 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Cow 5.8 pg/mL 23.5-1500 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$1,026.67
Details
Mouse 0.08 ng/mL 20-0.31 ng/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details
Guinea Pig 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 11 to 13 Days
$707.14
Details
Rabbit 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 11 to 13 Days
$707.14
Details
Monkey 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 11 to 13 Days
$707.14
Details
Dog 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 11 to 13 Days
$707.14
Details
Pig
  96 Tests Log in to see 11 to 13 Days
$707.14
Details
Sheep
  96 Tests Log in to see 11 to 13 Days
$707.14
Details

More ELISA Kits for COL2A1 Interaction Partners

Horse (Equine) Collagen, Type II, alpha 1 (COL2A1) interaction partners

  1. In contrast to previous studies using C2C the present study demonstrated that synovial levels of Coll2 (show SEMA3D ELISA Kits)-1 were significantly elevated in tarsocrural joints affected with osteochondrosis

  2. These results suggested that serum and synovial fluid (SF) collagen type II (CTX (show VSIG1 ELISA Kits)-II) concentrations and SF:serum CTX (show VSIG1 ELISA Kits)-II ratio may be used to detect cartilage degradation in horses with joint injury.

Rabbit Collagen, Type II, alpha 1 (COL2A1) interaction partners

  1. The expression of II type collagen and MMP-7 (show MMP7 ELISA Kits) is correlated to a retrogression of acetabular cartilage and increases obviously in early developmental dysplasia. [MMP7 (show MMP7 ELISA Kits)]

Mouse (Murine) Collagen, Type II, alpha 1 (COL2A1) interaction partners

  1. this study shows role of Del-1 in the regulation of platelet-monocyte interplay and the subsequent heterotypic aggregate formation in the blood-mediated inflammatory reaction in islet transplantation

  2. Alpha-tectorin (show TECTA ELISA Kits) and beta-tectorin (show TECTB ELISA Kits) crosslink type II collagen fibrils and connect the tectorial membrane to the spiral limbus.

  3. Col2 expression was seen in the prehypertrophic zone of the mandibular condyle cartilage.

  4. Rspo2 (show RSPO2 ELISA Kits) activates Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling to reduce Col2a1 and Sox9 (show SOX9 ELISA Kits) and to facilitate differentiation of proliferating chondrocytes into hypertrophic chondrocytes in growth cartilage

  5. The MC13 mutation in Col2a1 causes an incompletely penetrant splicing defect.

  6. The mutant G1170S Col2a1 gene in mice clearly alters the transgenic murine phenotype and cartilage matrix homeostasis.

  7. Data indicate that tamoxifen decreased collage type II COL2A1 by activating matrix metallopeptidases MMP-2 (show MMP2 ELISA Kits)/13 expression.

  8. The increased expressions of the cartilage-associated proteins Collagen2 and alpha-SMA (show SMN1 ELISA Kits) during scleral chondrogenesis accompany myopia development.

  9. Results indicate the ability of type II collagen (CII) to generate CII-specific anterior chamber-associated immune deviation (ACAID)-mediated immune tolerance in vivo and in vitro in both DBA/1 (show RPS19 ELISA Kits) mice and C57BL/6 mice.

  10. expression of the Col2a1 IIC splice form may have a regulatory function in controlling alternative splicing of exon 2 to generate defined proportions of IIA, IID and IIB procollagen isoforms during cartilage development

Human Collagen, Type II, alpha 1 (COL2A1) interaction partners

  1. Collagen type II loss is induced by the down-regulation of miR (show MLXIP ELISA Kits)-133a in intervertebral disc degeneration.

  2. Decrease in mRNA expression of COL2A1 is associated with Osteoarthritis.

  3. COL2A1 defects in OSTL1 are not confined to mutations in exon 2, c.2678dupC (p.Ala895Serfs*49) and c.3327+ 1G>C.

  4. study provide an updated list of COL2A1 mutations identified in the literature and in our patients with a genetic diagnosis for bone dysplasia; work confirmed that mutations in this gene are responsible for a wide clinical spectrum ranging from lethal major skeletal abnormalities to isolated arthritis

  5. Overexpression of miR (show MLXIP ELISA Kits)-27b promoted type II collagen expression in nucleus pulposus cells.

  6. Whole exome sequencing identified a novel COL2A1 mutation that causes mild Spondylo-epiphyseal dysplasia mimicking autosomal dominant brachyolmia

  7. Dysspondyloenchondromatosis is associated with COL2A1 mutation.

  8. Constitutive mutation in COL2A1 gene is associated with Kniest dysplasia and chondrosarcoma.

  9. Serum CTX (show CYP27A1 ELISA Kits)-II levels in human brucellosis were higher than those of healthy controls but serum CTX (show CYP27A1 ELISA Kits)-II levels in male patients were significantly higher than those of female patients indicating biological changes in cartilage and bone in human brucellosis.

  10. Results identified a novel COL2A1 variant (c.619G>A, p.Gly207Arg) causing a distinct type II collagenopathy with features of progressive pseudorheumatoid dysplasia and spondyloepiphyseal dysplasia, Stanescu type.

Pig (Porcine) Collagen, Type II, alpha 1 (COL2A1) interaction partners

  1. Data suggest that focal adhesion kinase (FAK)-SMAD 2/3 mediate signal crosstalk between type II collagen and TGF-beta1 and regulate glycosaminoglycan secretion in chondrocytic cells.

Cow (Bovine) Collagen, Type II, alpha 1 (COL2A1) interaction partners

  1. a first example of a dominant COL2A1 splice site variant as candidate causal mutation of a severe lethal chondrodysplasia (show COL11A1 ELISA Kits) phenotype

  2. Denaturation of the chimeric collagen increased its affinity for fibronectin (show FN1 ELISA Kits), as seen for mammalian collagens.

  3. Data show that expression of mRNAs for aggrecan (show ACAN ELISA Kits), collagen type II, and versican (show Vcan ELISA Kits) were significantly effected by the intervention.

  4. Data show that biglycan (show BGN ELISA Kits), collagen type I, collagen type II, decorin (show DCN ELISA Kits), and versican (show Vcan ELISA Kits) were significantly affected by vibration duration, frequency, and amplitude.

  5. specific ADAMTS-2 (show Adamts2 ELISA Kits) domains cleave the aminopropeptide of fibrillar procollagens types I-III and V

  6. Changes in aggrecan (show ACAN ELISA Kits) and type II collagen promoter activity in transfected chondrocyte-laden cylindrical constructs were evaluated in response to a range of loading frequencies and durations.

  7. SMase down-regulates type II collagen in articular chondrocytes via activation of the ERK signaling cascade, redistribution of SOX9, and recruitment of c-Fos

  8. Response of the chondrocyte to a cryptic sequence of denaturated type II collagen may play a role in naturally occurring hypertrophy in endochondral ossification and in the development of cartilage pathology in osteoarthritis.

  9. IGF-I (show IGF1 ELISA Kits) dose-dependently maintained cartilage formation

COL2A1 Antigen Profile

Antigen Summary

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Gene names and symbols associated with COL2A1

  • collagen, type II, alpha 1 (col2a1) antibody
  • collagen, type II, alpha 1 (col2a1b) antibody
  • collagen, type II, alpha 1 (COL2A1) antibody
  • collagen, type II, alpha 1 (Col2a1) antibody
  • type II Collagen (LOC100009005) antibody
  • ANFH antibody
  • AOM antibody
  • CB11 antibody
  • CG2A1A antibody
  • Col2 antibody
  • Col2a antibody
  • Col2a-1 antibody
  • COL2A1 antibody
  • col2a1a antibody
  • COL11A3 antibody
  • COLLII antibody
  • Del1 antibody
  • Dmm antibody
  • Lpk antibody
  • M100856 antibody
  • Rgsc856 antibody
  • SEDC antibody

Protein level used designations for COL2A1

alpha-1 type II collagen , collagen alpha-1(II) chain , alpha-1 type II' collagen , collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) , collagen, type II, alpha 1 , collagen alpha-1(II) chain-like , type II collagen , collagen type IIA , chondrocalcin , disproportionate micromelia , procollagen, type II, alpha 1 , cartilage collagen , collagen II, alpha-1 polypeptide , alpha 1 type II procollagen , alpha 1 type IIA collagen , procollagen alpha 1(II) , Procollagen II alpha 1 , collagen type II (Col2A1) gene, enhancer region , pro alpha1 type II collagen , collagen type II , type II collagen alpha1 , cyanogen bromide , pro-alpha 1(II)

GENE ID SPECIES
394828 Xenopus (Silurana) tropicalis
397739 Xenopus laevis
451860 Pan troglodytes
100433193 Pongo abelii
100474711 Ailuropoda melanoleuca
791241 Equus caballus
100008672 Oryctolagus cuniculus
100588525 Nomascus leucogenys
12824 Mus musculus
1280 Homo sapiens
395069 Gallus gallus
25412 Rattus norvegicus
100009005 Oryctolagus cuniculus
100733907 Cavia porcellus
397323 Sus scrofa
407142 Bos taurus
100860743 Capra hircus
403826 Canis lupus familiaris
100196905 Ovis aries
397738 Xenopus laevis
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