Complement Component 5a Receptor 1 (C5AR1) ELISA Kits

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Additionally we are shipping C5AR1 Antibodies (274) and C5AR1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
C5AR1 12273  
C5AR1 728 P21730
C5AR1 113959 P97520
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Top C5AR1 ELISA Kits at

Showing 4 out of 12 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.128 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 15 to 17 Days
Human 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
Rat 6.25 pg/mL 1600-25 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
  96 Tests Log in to see 15 to 18 Days

More ELISA Kits for C5AR1 Interaction Partners

Mouse (Murine) Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. C5aR1 facilities the pathogenesis of chronic kidney infection by enhancement of bacterial colonization of tubular epithelium, promotion of local inflammatory responses, and impairment of phagocytic function of monocytes/macrophages.

  2. Data indicate that complement component 5a receptor 1 protein (C5aR1) signaling in osteoblasts plays a detrimental role in bone regeneration after fracture.

  3. The role of C5aR1 and C5aR2 in response to renal ischemia-reperfusion injury is reported. The results also demonstrated that C5aR2 is a functional receptor, rather than a decoy receptor, and may provide a new target for intervention.

  4. these data reveal a differential role for C5aR during ethanol-induced liver inflammation and injury

  5. These findings demonstrate a complex regulation pattern of C5aR1 in the airways, lung tissue and mediastinal lymph nodes of mice, suggesting that the C5a/C5aR1 axis controls airway constriction and inflammation through activation of myeloid cells in all three compartments in an experimental model of allergic asthma.

  6. C5aR1-KO mice exhibited less renal injury, as evidenced by reduced albuminuria. In contrast, cardiac injury was accelerated with increased cardiac fibrosis and heart weight in C5aR1-deficient mice after ANG II (show AGT ELISA Kits) infusion. No effect was found on blood pressure. the C5a:C5aR1 axis drives end-organ damage in the kidney but protects from the development of cardiac fibrosis and hypertrophy in experimental hypertension.

  7. This study demonstrated that C5aR1 contributes to the acute inflammatory response elicited by infiltrating immune cells following pilocarpine status epilepticus.

  8. Regulation of complement 5a receptor (C5aR)-induced neutrophil chemotaxis via IgG1 immune complexes (ICs (show DNAI1 ELISA Kits)) depends on galectin-3 (show LGALS3 ELISA Kits).

  9. The C5a/C5aR pathway is essential for up-regulating SphK1 (show SPHK1 ELISA Kits) expression through p38 MAPK (show MAPK14 ELISA Kits) activation in acute liver mice.

  10. C5a bidirectionally amplifies TLR4 (show TLR4 ELISA Kits)-mediated NLRP3 (show NLRP3 ELISA Kits) inflammasome activation in monocytes while suppressing this pathway in macrophages. However, as C5aR1 deficiency attenuates the IL-1beta (show IL1B ELISA Kits) response to LPS (show TLR4 ELISA Kits) challenge in vivo, results suggest overall that C5a augments physiologic inflammasome responses.

Human Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. TLR4 (show TLR4 ELISA Kits) and C5aR crosstalk in dendritic cells induces a core regulatory network of RSK2 (show RPS6KA3 ELISA Kits), PI3Kbeta, SGK1 (show SGK1 ELISA Kits), and FOXO (show FOXO3 ELISA Kits) transcription factors.

  2. Results showed that 7-oxygenated cholesterol derivatives have differential effects on monocyte/macrophage expression of IL-8 (show IL8 ELISA Kits) and C5a receptor and that C5a receptor is involved in 7alphaOHChol-induced IL-8 (show IL8 ELISA Kits) expression via PI3K (show PIK3CA ELISA Kits) and MEK (show MAP2K1 ELISA Kits). Study demonstrated expression of IL-8 (show IL8 ELISA Kits) and C5a receptor primarily by 7alpha-hydroxycholesterol in monocytes/macrophages.

  3. Reducing RPS19 (show RPS19 ELISA Kits) in tumor cells or blocking the C5a receptor 1-RPS19 (show RPS19 ELISA Kits) interaction decreases RPS19 (show RPS19 ELISA Kits)-mediated immunosuppression, impairs tumor growth, and delays the development of tumors in a transgenic model of breast cancer

  4. C5aR expression in gastric cancer was associated with cancer progression, liver metastasis, and poor prognosis.

  5. this study shows that downregulation of CD88 after stimulation with IL-8 (show IL8 ELISA Kits) is more pronounced in adults than in neonates, whereas fMLP (show FPR1 ELISA Kits) induces changes in receptor expression that are of the same magnitude in neutrophils from neonates as from adults

  6. Relation of C5aR expression to tumor development and poor prognosis of the breast cancer patients

  7. The objective of the present study was to validate a receptor occupancy (RO) assay for a human anti-C5aR monoclonal antibody drug candidate, NNC0215-0384 (NN0384)

  8. These data thus suggest that C5aR1 acts as an enhancer of CCR5-mediated HIV entry into macrophages, the targeting of which may prove useful to reduce HIV infection by R5 strains.

  9. C5AR and C5L2 (show GPR77 ELISA Kits)-mediated neutrophil dysfunction is associated with a poor outcome in sepsis.

  10. that C5aR stimulates cell invasion and migration via ERK1/2 (show MAPK1/3 ELISA Kits)-mediated epithelial-mesenchymal transition in hepatocellular carcinoma cells

Cow (Bovine) Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. Studies provide information regarding distinct structural and functional features that may contribute to the unique pharmacological properties of bovine C5aR.

C5AR1 Antigen Profile

Antigen Summary

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Gene names and symbols associated with C5AR1

  • complement component 5a receptor 1 (C5AR1) antibody
  • complement component 5a receptor 1 (c5ar1) antibody
  • C5a anaphylatoxin chemotactic receptor-like (LOC100352978) antibody
  • complement component 5a receptor 1 (C5ar1) antibody
  • C5A antibody
  • C5AR antibody
  • C5AR1 antibody
  • C5r1 antibody
  • CD88 antibody
  • D7Msu1 antibody
  • GPR77 antibody

Protein level used designations for C5AR1

complement component 5a receptor 1 , C5a anaphylatoxin receptor , G protein-coupled receptor 77 , C5a anaphylatoxin chemotactic receptor 1 , C5a ligand , C5a-R , complement component 5, receptor 1 , complement component 5 receptor 1 , C5aR , complement C5a receptor , anaphylatoxin C5a receptor , complement component 5 receptor 1 (C5a ligand) , C5a anaphylatoxin chemotactic receptor

397287 Sus scrofa
430484 Gallus gallus
100379958 Xenopus (Silurana) tropicalis
100589337 Nomascus leucogenys
100352978 Oryctolagus cuniculus
12273 Mus musculus
728 Homo sapiens
113959 Rattus norvegicus
100135489 Cavia porcellus
442974 Canis lupus familiaris
718056 Macaca mulatta
468931 Pan troglodytes
100048955 Sus scrofa
493645 Bos taurus
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