Cystathionine-beta-Synthase (CBS) ELISA Kits

The protein encoded by CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. Additionally we are shipping Cystathionine-beta-Synthase Antibodies (123) and Cystathionine-beta-Synthase Proteins (30) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CBS 24250 P32232
CBS 12411 Q91WT9
CBS 875 P35520
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Top Cystathionine-beta-Synthase ELISA Kits at antibodies-online.com

Showing 4 out of 17 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 31.25 pg/mL 125-8000 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,026.67
Details
Mouse 0.059 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
$929.89
Details
Rat 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$910.56
Details
Rat 15.6-1000 ng/mL   96 Tests Log in to see 2 to 3 Days
$713.90
Details

Top referenced Cystathionine-beta-Synthase ELISA Kits

  1. Human CBS ELISA Kit for Sandwich ELISA - ABIN456995 : Sun, Sun, Li, Pan, Xie, Wang, Zhang: Potential biomarkers predicting risk of pulmonary hypertension in congenital heart disease: the role of homocysteine and hydrogen sulfide. in Chinese medical journal 2014 (PubMed)

More ELISA Kits for Cystathionine-beta-Synthase Interaction Partners

Chimpanzee Cystathionine-beta-Synthase (CBS) interaction partners

Mouse (Murine) Cystathionine-beta-Synthase (CBS) interaction partners

  1. showed that N-homocysteinylation of collagen in Cbs(-/-) mice impairs its cross-linking

  2. the findings of this study indicate that a deficiency in 3MST does not significantly affect endotoxemia, while a deficiency in CBS or CSE (show CTH ELISA Kits) slightly ameliorates the outcome of LPS (show TLR4 ELISA Kits)-induced endotoxemia in vivo.

  3. These data confirm a key role for the H2S-generating enzymes Cbs and Cth (show CTH ELISA Kits) in pulmonary vascular development and homeostasis and in lung alveolarization.

  4. genetic deficiency results in reduced Tet1 and Tet2 (show TET2 ELISA Kits) expression, which leads to hypermethylation of Foxp3 (show FOXP3 ELISA Kits), and impairment of Treg cell differentiation and immune homeostasis.

  5. Elevated homocytsteine levels in the CBS-/+ mouse skeletal muscles caused diminished anti-oxidant capacity and contributed to enhanced total protein as well as PGC-1alpha (show PPARGC1A ELISA Kits) specific nitrotyrosylation after ischemia.

  6. CBS disruption causes embryo retention and developmental delay in the mouse oviduct.

  7. CBS is present in adrenocortical cells and accounts for H2S generation in adrenal glands. CBS is critical for maintenance of mitochondrial function and glucocorticoid production in adrenal cortex.

  8. Elevating endogenous H2S via CBS over-expression in immortalized microglia not only reduced the expression of pro-inflammatory M1 genes, but also enhanced the anti-inflammatory M2 marker IL-10 (show IL10 ELISA Kits) production.

  9. Cbs protein expression is upregulated in brain cortex following traumatic brain injury.

  10. Brain of mice heterozygous for Cbs displays overexpression of DYR (show DHFR ELISA Kits) kinase and SAH (show ACSM3 ELISA Kits) hydrolase.

Human Cystathionine-beta-Synthase (CBS) interaction partners

  1. Inducible expression of CBS and CSE was found to be associated with a mineralizing phenotype in mesenchymal stem cells transitioning to mineralizing osteoblasts.

  2. SNPs in CBS were not related to relevant changes in homocysteine levels in coronary artery disease patients or controls.

  3. The CBS rs2124459 was associated with a reduced risk of cleft palate in both French and Belgian populations. These results highlight the prominent involvement of the vitamin B6-dependent transsulfuration pathway of homocysteine in orofacial cleft risk and the interest for evaluating vitamin B6 status in further population studies.

  4. There is no ordinary conjunction between human CBS and severe sepsis/septic shock, but CBS genotypes are involved in disease susceptibility.

  5. Oligomeric status of human cystathionine beta-synthase modulates AdoMet (show MAT1A ELISA Kits) binding.

  6. Significant interactions were observed among the methylenetetrahydrofolate reductase (MTHFR (show MTHFR ELISA Kits); C677T; A1298C) and cystathionine-beta-synthase (CBS; T833C/844ins68, G919A) polymorphisms in the results for homocysteine (Hcy) levels, where heterozygous had higher values.

  7. results indicate that binding of SAM (show TTN ELISA Kits) to regulatory and stabilizing sites in CBS may have evolved to display an exquisite thermodynamic and structural specificity towards SAM (show TTN ELISA Kits) as well as the ability to transduce the allosteric signal responsible for CBS activation.

  8. CBS 844ins68 polymorphisms were not associated with Oral squamous cell carcinoma risk in southeastern Brazilians.

  9. This is the first mutational analysis of CBS done in a Filipino patient with classic homocystinuria who presented with a novel duplication mutation and a novel missense mutation.

  10. Two novel compound heterozygous mutations in the CBS gene, c.407T > C (p. L136P) and c.473C > T (p.A158V), were identified in the three patients of a Han Chinese family with homocystinuria

Cow (Bovine) Cystathionine-beta-Synthase (CBS) interaction partners

  1. These findings indicate that greater synthesis of phosphatidylcholine (show SGMS1 ELISA Kits) and antioxidants contribute to the better performance and immuno-metabolic status in methionine-supplemented cows.

Cystathionine-beta-Synthase (CBS) Antigen Profile

Antigen Summary

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with CBS

  • cystathionine-beta-synthase (cbs-a) antibody
  • cystathionine-beta-synthase (cbs) antibody
  • cystathionine beta-synthase (Cbs) antibody
  • cystathionine-beta-synthase (CBS) antibody
  • cystathionine beta-synthase (CNA06170) antibody
  • cystathionine beta-synthase (Tb11.02.5400) antibody
  • cystathionine beta-synthase CBS (cbs) antibody
  • cystathionine beta-synthase (cbs) antibody
  • cystathionine beta-synthase (cysB) antibody
  • cystathionine beta synthase (Cbs) antibody
  • cystathionine-beta-synthase (cbs-b) antibody
  • cystathionine-beta-synthase b (cbsb) antibody
  • AI047524 antibody
  • AI303044 antibody
  • cb442 antibody
  • cbs antibody
  • DDBDRAFT_0189727 antibody
  • DDBDRAFT_0191292 antibody
  • DDB_0189727 antibody
  • DDB_0191292 antibody
  • GB12529 antibody
  • HIP4 antibody
  • wu:fb37g05 antibody
  • wu:fm61c07 antibody
  • wu:fq06c06 antibody
  • zgc:113704 antibody

Protein level used designations for CBS

cystathionine-beta-synthase , cystathionine beta-synthase , cystathionine beta-synthase CBS , beta-thionase , hemoprotein H-450 , serine sulfhydrase , methylcysteine synthase

GENE ID SPECIES
380308 Xenopus laevis
493533 Xenopus (Silurana) tropicalis
551341 Apis mellifera
736626 Pan troglodytes
3253577 Cryptococcus neoformans var. neoformans JEC21
3665875 Trypanosoma brucei brucei strain 927/4 GUTat10.1
4551426 Mycobacterium ulcerans Agy99
6228672 Mycobacterium marinum M
7006755 Rhodospirillum centenum SW
7705918 Gemmatimonas aurantiaca T-27
7712188 Rhodococcus erythropolis PR4
7746532 Rhodococcus opacus B4
8616308 Dictyostelium discoideum AX4
100136726 Oncorhynchus mykiss
100635325 Amphimedon queenslandica
24250 Rattus norvegicus
12411 Mus musculus
446655 Xenopus laevis
418545 Gallus gallus
875 Homo sapiens
611071 Canis lupus familiaris
514525 Bos taurus
100008766 Oryctolagus cuniculus
266987 Danio rerio
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