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The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Additionally we are shipping Cystatin C Antibodies (460) and Cystatin C Proteins (80) and many more products for this protein.
Showing 10 out of 115 products:
Pig (Porcine) CST3 ELISA Kit for Sandwich ELISA - ABIN415836
Witt, Glage, Schulz, Lichtinghagen, Simann, Pape, Sümpelmann: Impact of 6% hydroxyethyl starch 130/0.42 and 4% gelatin on renal function in a pediatric animal model. in Paediatric anaesthesia 2014
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Human CST3 ELISA Kit for Sandwich ELISA - ABIN577654
Barbati, Cappuccini, Aisa, Grasselli, Zamarra, Bini, Bellomo, Orlacchio, Di Renzo: Increased Urinary Cystatin-C Levels Correlate with Reduced Renal Volumes in Neonates with Intrauterine Growth Restriction. in Neonatology 2016
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Rat (Rattus) CST3 ELISA Kit for Sandwich ELISA - ABIN416114
Ucibior, Go??biowska, Adamczyk, Nied?wiecka, Fornal: The renal effects of vanadate exposure: potential biomarkers and oxidative stress as a mechanism of functional renal disorders--preliminary studies. in BioMed research international 2014
Human CST3 ELISA Kit for Sandwich ELISA - ABIN2683945
Alioglu, Saygi, Turk, Kirilmaz, Tuzun, Duman, Tengiz, Yildiz, Ercan: N-acetylcysteine in preventing contrast-induced nephropathy assessed by cystatin C. in Cardiovascular therapeutics 2013
Rat (Rattus) CST3 ELISA Kit for Sandwich ELISA - ABIN368226
Yu, Bian, Gu: Transplantation of insulin-producing cells to treat diabetic rats after 90% pancreatectomy. in World journal of gastroenterology 2015
Application of the cystatin C-based equations most accurately estimate glomerular filtration rate in Chinese patients with chronic kidney disease.
This study tested the utility of neutrophil gelatinase-associated lipocalin (NGAL (show LCN2 ELISA Kits)) and cystatin C (CysC) in addition to standard creatinine for early determination of Acute Kidney Injury (AKI) After Heart Operations Using Cardiopulmonary Bypass. The results support the notion that CysC and NGAL (show LCN2 ELISA Kits) should be viewed as comparable for early AKI detection.
The strong association between epicardial adipose tissue (EAT) and cystatin C demonstrated herein indicates that EAT accumulation may play an important role in Cystatin C secretion, possibly contributing to cardiometabolic risk in T2DM patients.
A high CysC level had predictive value regarding the severity of vascular lesions in acute coronary syndrome.
Elevated levels of cystatin C were detected in early diagnosis of right heart failure in patients with systemic sclerosis.
Data suggest that melanoma cells internalize/absorb cystatin C from culture media, leading to increased intracellular cystatin C levels; cystatin E/M (show CST6 ELISA Kits) is internalized as well but at modest rate due to down-regulation of cell migration; however, the effect of intracellular cystatin E/M (show CST6 ELISA Kits) on down-regulation of legumain (show LGMN ELISA Kits) activity is pronounced.
An elevated preoperative Cys (show DNAJC5 ELISA Kits)-C level was demonstrated to be related with worse survival in patients with renal cell carcinoma(RCC (show XRCC1 ELISA Kits)). Measuring preoperative serum Cys (show DNAJC5 ELISA Kits)-C might be a simple way for finding poor prognostic patients and patients with elevated preoperative Cys (show DNAJC5 ELISA Kits)-C level should be more closely followed up
Acute kidney injury is common following deliberate self-poisoning with a combination washing powder containing oxalic acid and potassium permanganate and cystatin C monitoring may under estimate the severity of poisoning.
Cystatin C significantly decreased the lipopolysaccharide-stimulated release and expression of interleukin-1beta and tumor necrosis factor-alpha (show TNF ELISA Kits) in monocyte and peripheral blood mononuclear cultures from healthy donors and Crohn's patients. Cystatin C was internalized by monocytes via an active endocytic process, decreased phosphorylation of the MAP kinase (show MAPK1 ELISA Kits) pathway ERK-1 (show MAPK3 ELISA Kits)/2, and altered surface markers.
Fibrillation of CysC therefore likely initiates from the monomer and does not require domain-swapping. The non-swapped oligomers likely represent a dead-end (show DND1 ELISA Kits) offshoot of the amyloid pathway and must dissociate to monomers prior to rearranging to amyloid fibrils. These prefibrillar CysC oligomers were potent inhibitors of aggregation of the Alzheimer's-related peptide, beta-amyloid.
CysC plays an important regulatory role in combating cell death via the autophagic pathway in atherosclerosis.
Data (including data from studies in mutant mice) suggest that up-regulation of Cst3, as observed in plasma of mice with type 2 diabetes, down-regulates insulin (show INS ELISA Kits) signaling and promotes endoplasmic reticulum stress in hepatocytes but not in myotubes.
Cystatin C is a potential pathogenic signal triggering neurodegeneration in multiple system atrophy.
The neuroprotective activity of CysC against Amyotrophic lateral sclerosis-linked mutant Cu/Zn-superoxide dismutase (SOD1 (show SOD1 ELISA Kits))-mediated toxicity.
an important role for macrophages, DC, and ROS (show ROS1 ELISA Kits) in diseases associated with the protease inhibitory activity or amyloidogenic properties of cystatin C.
APP (show APP ELISA Kits) expression stimulates NSPC proliferation; this effect is mediated via an increase in cystatin C secretion
Cystatin C, a protein targeted to the classical secretory pathway by its signal peptide sequence, is secreted by primary neurons in at least 9 different cystatin C glycoforms associated with exosomes.
The lack of cystatin C enhances Collagen-induced arthritis and primarily affects in vivo priming of the immune system
Inflammation causes downregulation of cystatin C expression in dendritic cells and reduces serum CstC levels.
Data show that the absence of cystatin C reduced epithelial cell apoptosis but increased proliferation in skin.
CST3 may be required to remodel endometrial and placental tissues for close apposition between maternal and fetal vasculatures and to facilitate transplacental transport of gases, micronutrients (amino acids, glucose), and macromolecules (proteins).
Increased production of cystatin C in osteoarthritis synovium does not alleviate synovitis or cartilage pathology.
Cystatin C in milk basic protein (MBP (show MBP ELISA Kits)) is suggested as one of the factors inhibiting bone resorption
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease.
, egg-white cystatin
, cystatin C
, cystatin 3
, hypothetical protein
, bA218C14.4 (cystatin C)
, neuroendocrine basic polypeptide
, Cystatin C (cysteine proteinase inhibitor)
, colostrum thiol proteinase inhibitor
, cystatin C (amyloid angiopathy and cerebral hemorrhage)