Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) ELISA Kits

CYP2A6, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2A6 Antibodies (105) and CYP2A6 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYP2A6 1548 P11509
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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.938 ng/mL 1.563-100 ng/mL 96 Tests Log in to see 12 to 14 Days

More ELISA Kits for CYP2A6 Interaction Partners

Pig (Porcine) Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) interaction partners

  1. Polymorphisms within the CYP2A6 gene are not a significant cause of high skatole levels.

Human Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) interaction partners

  1. CYP2A6*4 genetic polymorphisms may not strongly affect smoking behavior but may possibly have an effect on nicotine dependence

  2. CYP2A6 genetic variation alters striatal-cingulate circuits, network hubs, and executive processing in smokers. Because the CYP2A6 effect was seen only in smokers, these data suggest that the rate of nicotine metabolism-and thus the concentration of nicotine presented to the brain over the course of nicotine addiction-shapes brain circuits that, among other functions, compute reward and impulsivity processes.

  3. a greater CYP2A6 activity causes smokers to smoke more extensively and be exposed to higher levels of carcinogens, resulting in an increased risk for lung cancer.

  4. Gene Amplification and Potential Overexpression of Cyp2a5/CYP2A6 Are Associated with the Invasive Phenotype

  5. We conducted a genome-wide association study (GWAS) of plasma caffeine, paraxanthine, theophylline, theobromine and paraxanthine/caffeine ratio. A single SNP at 6p23 (near CD83 (show CD83 ELISA Kits)) and several SNPs at 7p21 (near AHR (show AHR ELISA Kits)), 15q24 (near CYP1A2 (show CYP1A2 ELISA Kits)) and 19q13.2 (near CYP2A6) met GW-significance (P < 5 x 10-8) and were associated with one or more metabolites

  6. study demonstrated a strong dose-dependent association between reduced CYP2A6 activity determined by genotypes and reduced risk of lung cancer

  7. Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank

  8. drug and the major metabolites were compared with the kinsenoside-cotreated samples. The effect of kinsenoside was negligible on the enzyme activity of all the CYP (show PPIG ELISA Kits) isozymes tested even though CYP2A6 was slightly inhibited at higher concentrations.

  9. CYP2A6 gene variants were associated with markedly reduced nicotine and cotinine clearances.

  10. CYP2A6 polymorphisms are associated with poor response to chemotherapy in gastric cancer.

CYP2A6 Antigen Profile

Antigen Summary

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3\; however, it has been renamed CYP2A6.

Gene names and symbols associated with CYP2A6

  • cytochrome P450 2A19 (CYP2A19) antibody
  • cytochrome P450, family 2, subfamily A, polypeptide 6 (CYP2A6) antibody
  • CPA6 antibody
  • CYP2A antibody
  • CYP2A3 antibody
  • CYP2A6 antibody
  • CYPIIA6 antibody
  • P450C2A antibody
  • P450PB antibody

Protein level used designations for CYP2A6

coumarin 7-hydroxylase , cytochrome p450 2A6 , 1,4-cineole 2-exo-monooxygenase , cytochrome P450 2A6 , cytochrome P450 IIA3 , cytochrome P450(I) , cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6 , flavoprotein-linked monooxygenase , xenobiotic monooxygenase

403149 Sus scrofa
1548 Homo sapiens
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