Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) ELISA Kits

CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C19 Antibodies (30) and CYP2C19 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYP2C19 1557 P33261
CYP2C19    
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Top CYP2C19 ELISA Kits at antibodies-online.com

Showing 2 out of 17 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 0.28 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 13 to 16 Days
$704.00
Details
Human 0.264 ng/mL 0.62-40 ng/mL 96 Tests Log in to see 13 to 16 Days
$589.47
Details

More ELISA Kits for CYP2C19 Interaction Partners

Human Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) interaction partners

  1. The poor metabolizer (PM) group had the lowest metabolic ratio and exhibited the highest area under the curve (AUC) for omeprazole among the CYP2C19 phenotype groups.

  2. The carriage of the cytochrome P450 (show CYP ELISA Kits) CYP2C19 681A allele rather than platelet receptor gene polymorphisms increased extent of platelet aggregation induced by dual antiplatelet therapy in patients with Coronary heart disease .

  3. coadministration, voriconazole AUC and Cmin decreased by 33% and 39% respectively, in CYP2C19 extensive-metabolizers, whereas voriconazole Cmax and AUC increased 4.4-fold and 5.6-fold respectively, in poor-metabolizers

  4. individuals with both the CYP2C19*2 allele and hypertension are at high risk of Clopidogrel Resistance during anti-thrombosis therapy.

  5. NXT (show NXT1 ELISA Kits) leaded to a significant enhancement of the CYP2C19 catalytic activity in PXR (show NR1I2 ELISA Kits)-transfected HepG2 cells

  6. The aim of this study was to clarify the catalytic activities of 31 CYP2C19 alleles on the oxidative in vitro metabolism of methadone. Methadone, as a CYP2C19-specific substrate, was used to systematically analyze the enzymatic characteristics of 31 CYP2C19 alleles found in the Chinese population, and offer valuable information relevant to the personalized medicine for CYP2C19-metabolized drugs in China.

  7. apart from the established association of the CYP2C19 *2 and *3 LOF alleles with high on-treatment platelet reactivity (HTPR), haplotypes of P2RY12 (show P2RY12 ELISA Kits) rs6798347, rs6787801, rs6801273, and rs6785930 rather than rs2046934 (T744C) that related to pharmacodynamics of clopidogrel in patients with ACS (show PLA2G15 ELISA Kits) were independently associated with HTPR

  8. CYP2C19 poor metabolizer genotype may be a new candidate risk factor for coronary microvascular disorder via inflammation exclusively in the female population.

  9. Poor metabolizer CYP2C19 variants are associated with microvascular angina.

  10. Variant genotypes of CYP2C19 are associated with an increased risk of esophageal squamous cell carcinoma in Kashmir, India.

CYP2C19 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Gene names and symbols associated with CYP2C19

  • cytochrome P450, family 2, subfamily C, polypeptide 19 (CYP2C19) antibody
  • CPCJ antibody
  • CYP2C antibody
  • P450C2C antibody
  • P450IIC19 antibody

Protein level used designations for CYP2C19

cytochrome P450 2C , (R)-limonene 6-monooxygenase , (S)-limonene 6-monooxygenase , (S)-limonene 7-monooxygenase , CYPIIC17 , CYPIIC19 , S-mephenytoin 4-hydroxylase , cytochrome P-450 II C , cytochrome P450 2C19 , cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19 , cytochrome P450-11A , cytochrome P450-254C , flavoprotein-linked monooxygenase , mephenytoin 4'-hydroxylase , mephenytoin 4-hydroxylase , microsomal monooxygenase , xenobiotic monooxygenase

GENE ID SPECIES
510380 Bos taurus
1557 Homo sapiens
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