Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C19 Antibodies (33) and CYP2C19 Proteins (3) and many more products for this protein.
Showing 3 out of 19 products:
Genetic testing of CYP2C19 may help in prescribing a dose according to genetic makeup and represent the initial steps towards the development of diagnostic tests and therapeutic strategies that will substantially improve human health.
rs4244285 of CYP2C19 have the main effects on coronary heart disease risk.
The poor metabolizer (PM) group had the lowest metabolic ratio and exhibited the highest area under the curve (AUC) for omeprazole among the CYP2C19 phenotype groups.
The carriage of the cytochrome P450 (show CYP ELISA Kits) CYP2C19 681A allele rather than platelet receptor gene polymorphisms increased extent of platelet aggregation induced by dual antiplatelet therapy in patients with Coronary heart disease .
coadministration, voriconazole AUC and Cmin decreased by 33% and 39% respectively, in CYP2C19 extensive-metabolizers, whereas voriconazole Cmax and AUC increased 4.4-fold and 5.6-fold respectively, in poor-metabolizers
individuals with both the CYP2C19*2 allele and hypertension are at high risk of Clopidogrel Resistance during anti-thrombosis therapy.
NXT (show NXT1 ELISA Kits) leaded to a significant enhancement of the CYP2C19 catalytic activity in PXR (show NR1I2 ELISA Kits)-transfected HepG2 cells
The aim of this study was to clarify the catalytic activities of 31 CYP2C19 alleles on the oxidative in vitro metabolism of methadone. Methadone, as a CYP2C19-specific substrate, was used to systematically analyze the enzymatic characteristics of 31 CYP2C19 alleles found in the Chinese population, and offer valuable information relevant to the personalized medicine for CYP2C19-metabolized drugs in China.
apart from the established association of the CYP2C19 *2 and *3 LOF alleles with high on-treatment platelet reactivity (HTPR), haplotypes of P2RY12 (show P2RY12 ELISA Kits) rs6798347, rs6787801, rs6801273, and rs6785930 rather than rs2046934 (T744C) that related to pharmacodynamics of clopidogrel in patients with ACS (show PLA2G15 ELISA Kits) were independently associated with HTPR
CYP2C19 poor metabolizer genotype may be a new candidate risk factor for coronary microvascular disorder via inflammation exclusively in the female population.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
cytochrome P450 2C
, (R)-limonene 6-monooxygenase
, (S)-limonene 6-monooxygenase
, (S)-limonene 7-monooxygenase
, S-mephenytoin 4-hydroxylase
, cytochrome P-450 II C
, cytochrome P450 2C19
, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19
, cytochrome P450-11A
, cytochrome P450-254C
, flavoprotein-linked monooxygenase
, mephenytoin 4'-hydroxylase
, mephenytoin 4-hydroxylase
, microsomal monooxygenase
, xenobiotic monooxygenase