Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by CRLF2 is a receptor for thymic stromal lymphopoietin (TSLP). Additionally we are shipping CRLF2 Antibodies (173) and CRLF2 Proteins (15) and many more products for this protein.
Showing 1 out of 7 products:
data suggest that this high frequency of genetic aberrations in the context of a high CRLF2 expression could contribute to the high risk of relapse in P2RY8 (show P2RY8 ELISA Kits)/CRLF2- and IGH/CRLF2-positive acute lymphoblastic leukemia.
CRLF2 overexpression is associated with childhood B-cell acute lymphoblastic leukemia.
CRLF2 gene rearrangement is associated with acute lymphoblastic leukemia.
TSLPR levels were found to be significantly higher in asthmatic than in nonasthmatic children. TSLPR expression in non-allergic asthmatic and allergic asthmatic groups was found to be significantly higher than in non-allergic nonasthmatic group
In adult B-cell acute lymphoblastic leukemia without recurrent fusion genes , high CRLF2 expression is associated with distinct clinico-biological features and an unfavourable prognosis
CD4 (show CD4 ELISA Kits)+ T cells from atopic dermatitis patients directly interacted with TSLP (show TSLP ELISA Kits) to produce a higher amount of IL-4 (show IL4 ELISA Kits) than those from normal subjects, and this action was attenuated with anti-TSLPR antibody
The levels of mRNA for TSLP (show TSLP ELISA Kits) and TSLPR were significantly elevated in parotid gland tissues from the KD group as compared to the control group.
Differences exist in the genetic profiles of Down syndrome-associated acute lymphoblastic leukemia patients in Japan and in Western countries, and that P2RY8 (show P2RY8 ELISA Kits)-CRLF2 and EBF1 (show EBF1 ELISA Kits) deletions may cooperate in leukemogenesis in a subset of Japanese DS-ALL patients.
CRLF2 overexpression (OE) was detected in 30 (18%) of 167 patients, the P2RY8-CRLF2 fusion was identified in only 3 (1.8%) of 167 patients, all of which demonstrated CRLF2 OE.
we report noncysteine in-frame mutations in IL7R (show IL7R ELISA Kits) and CRLF2 located in a region of the transmembrane domain closer to the cytosolic domain in acute lymphoblastic leukemias
A novel mouse xenograft model to study the role of TSLP (show TSLP ELISA Kits)-induced CRLF2 (show CRLF3 ELISA Kits) signals in normal and malignant human B lymphopoiesis has been developed.
High-cholesterol diet increased TSLPR expression and atherosclerosis. High-dose ticagrelor moderated this trend. It modulated platelet activity and atherosclerosis mediated by TSLPR, potentially through the PI3K/Akt (show AKT1 ELISA Kits) signal pathway.
Activating thymic stromal lymphopoietin (show TSLP ELISA Kits) promotes atherosclerosis by inducing Th17/Treg imbalance through TSLPR signaling in a mouse model.
Suggest that Treg defects in ApoE (show APOE ELISA Kits)(-/-) mice might partially be attributed to the disruption of TSLP (show TSLP ELISA Kits)-TSLPR-LAP signaling in epithelial cells and dendritic cells.
The structure of the mouse TSLP (show TSLP ELISA Kits)-mediated signaling complex reveals how TSLP (show TSLP ELISA Kits) establishes extensive interfaces with its cognate receptor (TSLPR).
TSLPR helps to create a permissive microenvironment for the development and pulmonary metastasis of mammary carcinoma in a mouse model using implanted 4T1 tumour cells.
A previously unrecognized role was found for TSLP (show TSLP ELISA Kits)/TSLPR signaling in type 2 immunity as an important enhancer for the development of alternately activated macrophages as well as for chemokine (show CCL1 ELISA Kits) production.
mice deficient in TSLP receptors on LCs abrogated the induction of OVA-specific IgE levels upon epicutaneous OVA sensitization.
Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient mice.
Presence of functional TSLP (show TSLP ELISA Kits)-specific receptor chain is required for the development of T helper cell type (Th)2 contact hypersensitivity to the hapten fluorescein isothiocyanate (FITC).
The protein encoded by this gene is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene.
cytokine receptor-like factor 2
, P2RY8/CRLF2 fusion
, TSLP receptor
, cytokine receptor CRL2 precusor
, cytokine receptor-like 2
, thymic stromal lymphopoietin protein receptor
, thymic stromal lymphopoietin receptor
, thymic stromal-derived lymphopoietin receptor
, cytokine receptor-like molecule 2
, delta 1
, lymphocyte antigen 114
, thymic stromal-derived lymphopoietin, receptor
, transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
, type I cytokine receptor delta 1