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anti-Defensin, alpha 1 (DEFA1) Antibodies

Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Additionally we are shipping alpha Defensin 1 Kits (12) and alpha Defensin 1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DEFA1 1667 P59665
DEFA1 13216 P11477
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Top anti-alpha Defensin 1 Antibodies at

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (fro), IHC (p)   0.1 mg Log in to see 6 to 8 Days
Human Goat Un-conjugated EIA, IHC (p), WB AP23709PU-N DEFA1/3 antibody staining of paraffin embedded Human Thymus at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. AP23709PU-N DEFA1/3 antibody staining of Human Spleen lysate at 2 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry analyzes of Defensin alpha-1 antibody in paraffin-embedded human breast carcinoma tissue. 0.1 mg Log in to see 6 to 8 Days
Human Goat Un-conjugated IHC (p), ELISA, WB Human Thymus, Myeloid Cells: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of Defensin alpha 1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Defensin alpha 1 expression in human spleen (A) whole cell lysates. 200 μL Log in to see 9 Days
Human Mouse Un-conjugated EIA, WB   1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
Human Goat Un-conjugated IHC (p), Neut, ELISA, WB Anti-DEFA1 / NP-1 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101107 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
Human Mouse Un-conjugated WB   1 mg Log in to see 4 to 5 Days

DEFA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,
Mouse (Murine) ,

Top referenced anti-alpha Defensin 1 Antibodies

  1. Human Monoclonal alpha Defensin 1 Primary Antibody for IHC (fro), IHC (p) - ABIN118975 : Schluesener, Meyermann: Neutrophilic defensins penetrate the blood-brain barrier. in Journal of neuroscience research 1996 (PubMed)
    Show all 5 references for ABIN118975

More Antibodies against alpha Defensin 1 Interaction Partners

Human Defensin, alpha 1 (DEFA1) interaction partners

  1. HNP1 functions as a "molecular brake" on macrophage-driven inflammation, ensuring both pathogen clearance and the resolution of inflammation with minimal bystander tissue damage.

  2. HP1 binding to the chromosomal passenger complex becomes particularly important when Aurora B (show AURKB Antibodies) phosphorylates kinetochore targets to eliminate erroneous microtubule attachments

  3. data demonstrate that HNP-1 induces IL-8 (show IL8 Antibodies) production not only through P2Y6 (show P2RY6 Antibodies), but also through additional P2 receptors via an ERK1/2 (show MAPK1/3 Antibodies)-dependent mechanism in intestinal epithelial cells.

  4. Results showed that NO and NaNO2 can be considered as factors regulating the chemoattractant properties of defensin (show DEF Antibodies) HNP1 in neutrophils

  5. Overexpression of DEFA1 retained independent prognostic significance for B-ALL outcome.

  6. Defensins promote the differentiation into activated CD91 (show LRP1 Antibodies)(bright) dendritic cells.

  7. Elevated DEFA1 levels in diabetes are independent of DEFA1 copy numbers.

  8. binding of HNP1 to affected bacterial toxins caused their local unfolding, potentiated their thermal melting and precipitation, exposed new regions for proteolysis, and increased susceptibility to collisional quenchers.

  9. The AD-1 (show APP Antibodies) assay offers another test with high sensitivity and specificity for diagnosing a prosthetic joint infection.

  10. The concentrations of LL37, alpha-1, beta-1 and beta-2 defensins were determined by ELISA. Serum AMPs (show ADSL Antibodies) did not change during attacks and did not correlate with acute phase reactants.

Mouse (Murine) Defensin, alpha 1 (DEFA1) interaction partners

  1. Decreased alpha-defensin (show DEF Antibodies) is associated with intestinal inflammation in a model of inflammatory bowel disease.

  2. cryptdin-1 and cryptdin-4 exhibit circadian oscillation

  3. the Arg5-Glu13 salt bridge in alpha-defensin (show DEF Antibodies) is conserved for defensin (show DEF Antibodies) in vivo stability

  4. MMP-7 (show MMP7 Antibodies) activates mouse paneth cell pro-alpha-defensins

alpha Defensin 1 (DEFA1) Antigen Profile

Protein Summary

Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Gene names and symbols associated with DEFA1

  • defensin, alpha 1 (DEFA1) antibody
  • defensin 1 (Def1) antibody
  • defensin, alpha 1 (Defa1) antibody
  • defensin, alpha 1B (DEFA1B) antibody
  • Def antibody
  • DEF1 antibody
  • DEFA1 antibody
  • DEFA2 antibody
  • Defcr antibody
  • Defcr1 antibody
  • GB19392 antibody
  • HNP-1 antibody
  • HP-1 antibody
  • HP1 antibody
  • MRS antibody

Protein level used designations for DEFA1

alpha-defensin 1 , defensin alpha 1 , defensin alpha 2 , Paneth cell-specific alpha-defensin 2 , defensin-1 , royalisin , defensin, alpha 1, myeloid-related sequence , defensin, alpha 2 , myeloid-related sequence , neutrophil defensin 1 , cryptdin-1 , defensin related cryptdin peptide 1 , defensin-related cryptdin peptide

100126731 Papio anubis
100126732 Papio anubis
100307002 Equus caballus
406143 Apis mellifera
1667 Homo sapiens
13216 Mus musculus
742808 Pan troglodytes
728358 Homo sapiens
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