anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Antibodies

Probably involved in mitochondrial protein import. Additionally we are shipping DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Kits (44) and DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DNAJB1 171221  
DNAJB1 81489 Q9QYJ3
DNAJB1 361384  
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Top anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Antibodies at

Showing 10 out of 324 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB DNAJB1 antibody - N-terminal region (ARP54795_P050) Catalog Number: ARP54795_P050  Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue  Observed Staining: Nucleus of pneumocytes Primary Antibody Concentration: 1:100  Secondary Antibody: Donkey anti-Rabbit-Cy3  Secondary Antibody Concentration: 1:200  Magnification: 20X  Exposure Time: 0.5 - 2.0 sec WB Suggested Anti-DNAJB1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of HSP40 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of HSP40 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
Human Mouse Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
Yeast Mouse Un-conjugated IP, ELISA, WB Hsp40 (YDJ1 2A7 H6), 0. 100 μg Log in to see 2 to 3 Days
Human Mouse Un-conjugated FACS, IF, IHC, WB HEK293T cells transfected with either RC201762 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-DNAJB1 antibody (ABIN2454060), and then analyzed by flow cytometry. Anti-DNAJB1 mouse monoclonal antibody (ABIN2454060) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DNAJB1 (RC201762). 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from COLO205 cells, using HSP40 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using HSP40 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Plasmodium falciparum Rabbit Un-conjugated ICC, IF, WB Hsp40 (Pf11_01513), malarial parasite lysate. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 16 Days
Human Mouse Un-conjugated ICC, IF, IP, IHC, ELISA, WB   100 μg Log in to see 2 to 3 Days

DNAJB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Antibodies

  1. Human Polyclonal DNAJB1 Primary Antibody for IHC (p), WB - ABIN1882092 : Ohtsuka, Hata: Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. in Cell stress & chaperones 2001 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal DNAJB1 Primary Antibody for FACS, IF - ABIN2454060 : Ramdzan, Polling, Chia, Ng, Ormsby, Croft, Purcell, Bogoyevitch, Ng, Gleeson, Hatters: Tracking protein aggregation and mislocalization in cells with flow cytometry. in Nature methods 2012 (PubMed)

  3. Human Polyclonal DNAJB1 Primary Antibody for ICC, IF - ABIN361670 : Hattori, Liu, Tohnai, Ueda, Kaneda, Kobayashi, Tanabe, Ohtsuka: Intracellular localization and partial amino acid sequence of a stress-inducible 40-kDa protein in HeLa cells. in Cell structure and function 1992 (PubMed)
    Show all 8 Pubmed References

More Antibodies against DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Interaction Partners

Human DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) interaction partners

  1. These studies demonstrate an important role for cellular chaperone Hsp40/DnaJB1 in influenza A virus life cycle by assisting nuclear trafficking of viral ribonucleoproteins.

  2. DNAJB1-PRKACA (show PRKACA Antibodies) was evaluated as a key driver of fibrolamellar carcinoma and as a candidate therapeutic target

  3. siRNA experiments confirmed that a reduction in Hsp27 (show HSPB1 Antibodies) or Hsp40 rescued CFTR (show CFTR Antibodies) in the DeltaF508 mutant, but the rescue was not additive or synergistic with C4 + 18 treatment, indicating these correctors shared a common pathway for rescue

  4. study provides a new molecular mechanism to regulate EGFR (show EGFR Antibodies) signaling through modulation of MIG6 (show ERRFI1 Antibodies) by DNAJB1 as a negative regulator.

  5. Whole exome sequencing followed by immunohistochemistry of fibrolamellar hepatocellular carcinoma cell lines and tumors showed two structural variants resulting in fusion transcripts: DNAJB1-PRKCA (show PKCa Antibodies) and CLPTM1L (show CLPTM1L Antibodies)-GLIS3 (show GLIS3 Antibodies).

  6. In this cohort of fibrolamellar hepatocellular carcinoma, almost 80% contained the DNAJB1-PRKACA (show PRKACA Antibodies) fusion transcript.

  7. Authors identified DNAJB1 as a negative regulator of PDCD5 (show PDCD5 Antibodies)-mediated apoptosis and found that the apoptosis network of PDCD5 (show PDCD5 Antibodies) regulates cancer cell death.

  8. We also found that, despite an initial report to the contrary, the human homolog of Sis1, Hdj1, is capable of [PSI+] prion (show PRNP Antibodies) propagation in place of Sis1

  9. HSP40 interacts with pyruvate kinase M2 and regulates glycolysis and cell proliferation in tumor cells.

  10. Studies with specific phosphoantibodies indicate that MK5 (show MAPKAPK5 Antibodies) phosphorylates Hsp40/DnaJB1 in vivo at Ser (show SIGLEC1 Antibodies)-149 or/and Ser (show SIGLEC1 Antibodies)-151 and Ser (show SIGLEC1 Antibodies)-171 in the C-terminal domain of Hsp40/DnaJB1.

Fruit Fly (Drosophila melanogaster) DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) interaction partners

  1. our data indicate that the MLF/DnaJ-1-dependent increase in Lz level allows the repression of Notch (show NOTCH1 Antibodies) expression and signaling to prevent aberrant blood cell development. Thus our findings establish a functional link between MLF and the co-chaperone DnaJ-1 to control RUNX transcription factor activity and Notch (show NOTCH1 Antibodies) signaling during blood cell development in vivo.

  2. Additional studies established that the increased toxicity upon mutating UbS2 stems from disrupting the autoprotective role that pathogenic ataxin-3 (show ATXN3 Antibodies) has against itself, which depends on the co-chaperone, DnaJ-1. Our data reveal a previously unrecognized balance between pathogenic and potentially therapeutic properties of the ataxin-3 (show ATXN3 Antibodies)-Rad23 interaction; they highlight this interaction as critical for the toxicity of the S

  3. Through DnaJ-1, our data connect ataxin-3 (show ATXN3 Antibodies) and Rad23 to protective processes involved with protein folding rather than increased turnover of toxic polyQ species.

  4. Expression of DnaJ-1 potently suppresses alpha1ACT-dependent degeneration , concomitant with decreased aggregation of the pathogenic protein. Mutating the nuclear importer karyopherin a3 also leads to reduced toxicity from pathogenic CACNA1A (show CACNA1A Antibodies)

  5. HSP40 and HSP110 (show HSPH1 Antibodies) function together in protein homeostasis control.

  6. A high positive correlation was found between the levels of Hsp40 expression and scores of basal and induced thermotolerance, implying a significant contribution of Hsp40 gene in thermoadaptation.

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) interaction partners

  1. Overexpression of DNAJB1 relieves TDP-43 (show TARDBP Antibodies) mediated toxicity in primary rodent cortical neurons.

  2. a biochemical link between Hsp40 expression and Abeta (show APP Antibodies)(42) proteostasis that is cell specific

  3. Hsc70 (show HSPA8 PLURAL_@19415@), Hdj1 and Hdj2 (show DNAJA1 PLURAL_@19415@) interact with soluble and fibrillar alpha-synuclein (show SNCA PLURAL_@19415@)

  4. Hsp40, which was constitutively expressed in postmeiotic spermatogenic cells in testis, was integrated into spermatozoa as two components, that is, sperm head and tail of rodent spermatozoa.

  5. HSP-40 expression was detected after 2 h of heat stress

  6. a role for Hsp40 crosstalk with CSPalpha in neuroprotection.

  7. This is a paper that uses purification techiques to find the following: Hsc40 (show DNAJB5 Antibodies), a new member of the hsp40 family, exhibits similar expression profile to that of hsc70 (show HSPA8 Antibodies) in mammalian cells.

DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Antigen Profile

Protein Summary

Probably involved in mitochondrial protein import. Is also required for efficient translocation of pre-pro-alpha-factor. Involved in heme regulation of HAP1, as a component of the high- molecular-weight (HMC) complex.

Gene names and symbols associated with DNAJB1

  • DnaJ (Hsp40) homolog, subfamily B, member 1 pseudogene 1 (DNAJB1P1) antibody
  • DnaJ-like-1 (DnaJ-1) antibody
  • DnaJ (Hsp40) homolog, subfamily B, member 1 (dnajb1) antibody
  • Hsp40 protein (Hsp40) antibody
  • Ydj1p (YDJ1) antibody
  • DnaJ protein (dnaJ) antibody
  • heat shock protein 40 (hsp40) antibody
  • DnaJ (Hsp40) homolog, subfamily B, member 1 (DNAJB1) antibody
  • DnaJ (Hsp40) homolog, subfamily B, member 1 (Dnajb1) antibody
  • 0610007I11Rik antibody
  • anon-WO0140519.166 antibody
  • anon-WO0172774.135 antibody
  • CG10578 antibody
  • dhdj-1 antibody
  • dhdj1 antibody
  • dHDJ1/HSP40 antibody
  • Dmel\\CG10578 antibody
  • dnaJ antibody
  • dnaJ-1 antibody
  • DnaJ-5 antibody
  • DNAJ1 antibody
  • DnaJ1 64EF antibody
  • DNAJB1P antibody
  • dnajb4 antibody
  • droj1 antibody
  • EU3500 antibody
  • hdj1 antibody
  • Hsp-40 antibody
  • hsp40 antibody
  • HSP40/HDJ1 antibody
  • HSPF1 antibody
  • MAS5 antibody
  • psiHSP40 antibody
  • RSPH16B antibody
  • Sis1 antibody

Protein level used designations for DNAJB1

CG10578-PA , CG10578-PB , DnaJ-1-PA , DnaJ-1-PB , Hsp40 , dnaJ like1 , Hsp40 protein , DnaJ protein , heat shock protein 40 , DnaJ (Hsp40) homolog, subfmaily B, member 1 , dnaJ homolog subfamily B member 1 , dnaJ protein homolog 1 , hDj-1 , heat shock 40 kDa protein 1 , heat shock 40kD protein 1 , human DnaJ protein 1 , radial spoke 16 homolog B

171221 Homo sapiens
38643 Drosophila melanogaster
493474 Xenopus (Silurana) tropicalis
692539 Bombyx mori
855661 Saccharomyces cerevisiae S288c
1003643 Staphylococcus aureus subsp. aureus MW2
1473367 Methanosarcina acetivorans C2A
3337 Homo sapiens
81489 Mus musculus
476688 Canis lupus familiaris
538426 Bos taurus
361384 Rattus norvegicus
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