Emerin Proteins (EMD)

Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. Additionally we are shipping Emerin Antibodies (132) and Emerin Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EMD 2010 P50402
EMD 13726 O08579
Rat EMD EMD 25437 Q63190
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Top Emerin Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

EMD Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Emerin (EMD) Interaction Partners

Fruit Fly (Drosophila melanogaster) Emerin (EMD) interaction partners

  1. bocks is a nonessential gene; complete loss of Bocks causes no overt developmental defects

Xenopus laevis Emerin (EMD) interaction partners

Human Emerin (EMD) interaction partners

  1. results indicate that emerin negatively regulates Notch (show NOTCH1 Proteins) signaling by promoting the retention of the NICD (show NOTCH1 Proteins) at the nuclear membrane

  2. It has been concluded that the LEM domain, responsible for binding to the chromatin protein BAF (show BANF1 Proteins), undergoes a conformational change during self-assembly of emerin N-terminal region.

  3. Association of emerin with nuclear BAF (show BANF1 Proteins) in cells required the LEM domain (residues 1-47).

  4. These data suggest a new role of EMD as an enhancer of autophagosome formation in the C16-ceramide autophagy pathway in colon cancer cells.

  5. Results highlight the interactions at the nuclear envelope where mutations in the EMD and TMPO (show TMPO Proteins) gene in combination with mutations in SUN1 (show SUN1 Proteins) have an impact on several components of the network.

  6. Emerin, a conserved LEM-domain protein, is among the few nuclear membrane proteins for which extensive basic knowledge--biochemistry, partners, functions, localizations, posttranslational regulation, roles in development and links to human disease

  7. the nucleoplasmic domains of Samp1 and Emerin can bind directly to each other.

  8. Findings show a novel EMD deletion causing rare clinical presentations which broaden the heterogeneous spectrum of phenotypes attributed to EMD mutations and provide new insight of genotype-phenotype correlations between EMD mutations and EDMD symptoms.

  9. Emerin and BAF (show BANF1 Proteins) associated only in histone- and lamin-B (show LMNB1 Proteins)-containing fractions. The S173D mutation specifically and selectively reduced GFP-emerin association with BAF (show BANF1 Proteins) by 58%

  10. Immunofluorescence assay and biochemical analysis of infected or transfected cells showed that Kaposi's sarcoma-associated herpesvirus p29 (show PRTN3 Proteins) expression resulted in delocalization and hyperphosphorylation of emerin.

Mouse (Murine) Emerin (EMD) interaction partners

  1. changes in nuclear size and shape, which are mediated by nuclear envelope structural proteins lamin A/C (show LMNA Proteins) and/or emerin, also impact gene regulation and lineage differentiation in early embryos.

  2. Results suggest that emerin protein is an essential component of the cellular apparatus constraining and fine-tuning Wnt/b-catenin signaling in the heart providing tight control of cardiomyocyte numbers.

  3. emerin functions with myosin IIB to polarize actin flow and nuclear movement in fibroblasts, suggesting a novel function for the nuclear envelope in organizing directional actin flow and cytoplasmic polarity.

  4. Interactions between HDAC3 (show HDAC3 Proteins) and Emerin mediate the interaction of myogenic regulatory loci with the nuclear lamina.

  5. a novel mechanism that could provide insight into the disease aetiology for the cardiac phenotype in many laminopathies, whereby lamin A/C and emerin regulate gene expression through modulation of nuclear and cytoskeletal actin polymerization

  6. report significant perturbations in the expression and activation of p38/Mapk14 (show MAPK14 Proteins) in emerin-null myogenic progenitors, showing that perturbed expression of Wnt (show WNT2 Proteins), IGF-1 (show IGF1 Proteins), TGF-beta (show TGFB1 Proteins), and Notch (show NOTCH1 Proteins) signaling components disrupts normal downstream myogenic signaling

  7. emerin facilitates repressive chromatin formation at the nuclear periphery by increasing the catalytic activity of HDAC (show HDAC3 Proteins)

  8. Perturbation to or total loss of the emerin-beta-catenin (show CTNNB1 Proteins) complex compromises both intercalated disc function and beta-catenin (show CTNNB1 Proteins) signalling in cardiomyocytes.

  9. These findings suggest roles for emerin as a downstream effector and signal integrator for tyrosine kinase (show TYRO3 Proteins) signaling pathway(s) at the nuclear envelope.

  10. emerin and lamin A/C are bound to actin at the late stages of myotube differentiation

Emerin (EMD) Protein Profile

Protein Summary

Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.

Gene names and symbols associated with Emerin Proteins (EMD)

  • emerin (EMD)
  • emerin (Emery-Dreifuss muscular dystrophy) (emd)
  • CG9424 gene product from transcript CG9424-RA (bocksbeutel)
  • emerin (emd-a)
  • emerin (emd-b)
  • emerin (emd)
  • emerin-like (LOC100415714)
  • emerin (Emd)
  • emerin-like (LOC492249)
  • AW550900 protein
  • Bocks protein
  • Bocksbeutel protein
  • CG9424 protein
  • Dmel\\CG9424 protein
  • EDMD protein
  • emd protein
  • emerin protein
  • fj58f01 protein
  • LEMD5 protein
  • Sta protein
  • wu:fj58f01 protein
  • xemd1 protein
  • xemd2 protein
  • xemerin1 protein
  • xemerin2 protein

Protein level used designations for Emerin Proteins (EMD)

emerin (Emery-Dreifuss muscular dystrophy) , emerin , CG9424-PA , CG9424-PB , bocksbeutel-PA , bocksbeutel-PB , xemerin1 , xemerin2 , emerin-like , LEM domain containing 5

465938 Pan troglodytes
558212 Danio rerio
699400 Macaca mulatta
100137262 Papio anubis
100328755 Oryctolagus cuniculus
41162 Drosophila melanogaster
733232 Xenopus laevis
733233 Xenopus laevis
100127712 Xenopus (Silurana) tropicalis
100415714 Callithrix jacchus
2010 Homo sapiens
13726 Mus musculus
25437 Rattus norvegicus
399681 Bos taurus
492249 Canis lupus familiaris
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