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Endothelial PAS Domain Protein 1 (EPAS1) ELISA Kits

EPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. Additionally we are shipping EPAS1 Antibodies (176) and EPAS1 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EPAS1 2034 Q99814
EPAS1 13819 P97481
EPAS1 29452 Q9JHS1
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Top EPAS1 ELISA Kits at antibodies-online.com

Showing 3 out of 13 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.059 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse 0.056 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details
Rat 30 pg/mL 78.13-5000 pg/mL 96 Tests Log in to see 9 to 11 Days
$800.00
Details

More ELISA Kits for EPAS1 Interaction Partners

Human Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. CCL5 (show CCL5 ELISA Kits) signals from infiltrating bone marrow mesenchymal stem cells to HIF2alpha signals within prostate cancer (PCa (show FLVCR1 ELISA Kits)) cells might play a key role to increase PCa (show FLVCR1 ELISA Kits) stem cell population and PCa (show FLVCR1 ELISA Kits) metastasis via altering the androgen receptor (show AR ELISA Kits) signals

  2. Data indicate that both hypoxia inducible factor 1 alpha subunit (HIF-1alpha (show HIF1A ELISA Kits)) and hypoxia-inducible factor 2 alpha (HIF-2alpha) play a role in the metastatic cascade in these two cell lines.

  3. results are consistent with distant shared ancestry for African and Asian EPAS1 haplotypes and Denisovan adaptive introgression

  4. Demonstrate that mTORC1 inhibition leads to AKT (show AKT1 ELISA Kits) activation and an increase in HIF2A expression, leading to chondrogenic differentiation of amniotic fluid stem cells.

  5. Most human soft tissue sarcomas have lower levels of EPAS1 expression relative to normal tissue.

  6. these data reveal a novel mechanism for the regulation of the expression of HIF2a, demonstrating that the HIF2a promoter is regulated by E2F1 (show E2F1 ELISA Kits) directly and that Cezanne regulates HIF2a expression through control of E2F1 (show E2F1 ELISA Kits) levels

  7. HIF2alpha-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma

  8. although Hif-1alpha (show HIF1A ELISA Kits) and Hif-2alpha synergize to suppress the development of acute myeloid leukemia (show BCL11A ELISA Kits), they are not required for leukemic stem cells maintenance.

  9. the genetic polymorphism of the EPAS1 gene may lead to variation of its gene expression levels to drive progression of the cancer and serve as a prognostic marker for NSCLC.

  10. The associations between HIF2A variants and different level of high altitude support that extremely high-altitude hypoxia challenge imposes selective effects on HIF2A variants among native Tibetans.

Mouse (Murine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. genetic analysis suggests that tubulointerstitial cellular crosstalk modulates renal EPO (show EPO ELISA Kits) production under conditions of epithelial HIF activation in the kidney.

  2. Chondrocytes co-cultured with HIF-2alpha-overexpressing fibroblast-like synoviocytes exhibited upregulation of Mmp3 (show MMP3 ELISA Kits) and Mmp13 (show MMP13 ELISA Kits), which is similar to the effects induced by interleukin (IL)-6 (show IL6 ELISA Kits) treatment of chondrocytes.

  3. HIF-2alpha inhibits high-grade soft tissue sarcoma cell growth. Loss of HIF-2alpha promotes sarcoma proliferation and increases calcium and mTORC1 signalling in undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma.

  4. HIF-2alpha-deficient mice displayed brown adipose tissue dysregulation, associated with reduced levels of uncoupling protein 1 (UCP1 (show UCP1 ELISA Kits)) and a dysfunctional thermogenic response to cold exposure.

  5. Loss of Hif-2alpha Rescues the Hif-1alpha (show HIF1A ELISA Kits) Deletion Phenotype of Neonatal Respiratory Distress In Mice

  6. although Hif-1alpha (show HIF1A ELISA Kits) and Hif-2alpha synergize to suppress the development of acute myeloid leukemia (show BCL11A ELISA Kits), they are not required for leukemic stem cells maintenance.

  7. Letter: HIF2alpha is expressed in a distinct spatial and temporal pattern throughout venous thrombus resolution.

  8. Results show that HIF2-a is up regulated in an in vitro model of nicotine plus lipopolysccharide-stimulated periodontal ligament cell line and primary culture. Its inhibition exhibits anti-inflammatory activity.

  9. High expression of HIF-2A is associated with leukemia and lymphoma.

  10. HIF2alpha has a cardiomyogenesis-promoting effect in embryonic stem cells via enhancing the activation of the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway.

Pig (Porcine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. immunostaining for HIF-1alpha (show HIF1A ELISA Kits) and HIF-2alpha was observed during endochondral ossification; only HIF-2alpha was present at sites of intramembranous ossification

Cow (Bovine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. There was an association of an EPAS1 (HIF2alpha) double variant in the oxygen degradation domain of EPAS1 in Angus cattle with high altitude pulmonary hypertension (HAPH). There was upregulation of 26 of 27 HIF2alpha target genes in EPAS1 carriers with HAPH.

EPAS1 Antigen Profile

Antigen Summary

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

Gene names and symbols associated with EPAS1

  • endothelial PAS domain protein 1 (EPAS1) antibody
  • endothelial PAS domain protein 1 (epas1) antibody
  • endothelial PAS domain protein 1 (Epas1) antibody
  • bhlhe73 antibody
  • ecyt4 antibody
  • EPAS antibody
  • EPAS-1 antibody
  • EPAS1 antibody
  • HIF-2alpha antibody
  • hif2 antibody
  • hif2a antibody
  • hif2alpha antibody
  • hlf antibody
  • HRF antibody
  • mop2 antibody
  • pasd2 antibody

Protein level used designations for EPAS1

endothelial PAS domain protein 1 , endothelial PAS domain-containing protein 1-like , EPAS-1 , HIF-1-alpha-like factor , HIF-1alpha-like factor , HIF-2-alpha , HIF2-alpha , PAS domain-containing protein 2 , basic-helix-loop-helix-PAS protein MOP2 , class E basic helix-loop-helix protein 73 , endothelial PAS domain-containing protein 1 , hypoxia-inducible factor 2 alpha , hypoxia-inducible factor 2-alpha , member of PAS protein 2 , HIF-related factor , HIF1 alpha-like factor , HIF1alpha-like factor , HLF (HIF1alpha-like factor) , Hif like protein , hypoxia inducible transcription factor 2alpha , mHLF , HIF-2 alpha , HIF2 alpha , hypoxia inducible factor 2, alpha subunit , hypoxia inducible factor 2a , HIF-2alpha

GENE ID SPECIES
459204 Pan troglodytes
714641 Macaca mulatta
100220014 Taeniopygia guttata
100396711 Callithrix jacchus
100439667 Pongo abelii
100543912 Meleagris gallopavo
100551891 Anolis carolinensis
100606638 Nomascus leucogenys
2034 Homo sapiens
13819 Mus musculus
29452 Rattus norvegicus
444145 Xenopus laevis
395596 Gallus gallus
474578 Canis lupus familiaris
100037272 Sus scrofa
282711 Bos taurus
100068622 Equus caballus
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