Energy Homeostasis Associated Proteins (ENHO)

Involved in the regulation of glucose homestasis and lipid metabolism (By similarity). Additionally we are shipping Energy Homeostasis Associated Antibodies (26) and Energy Homeostasis Associated Kits (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ENHO 500443 Q8K1D8
ENHO 375704 Q6UWT2
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Top Energy Homeostasis Associated Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days

ENHO Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

More Proteins for Energy Homeostasis Associated (ENHO) Interaction Partners

Mouse (Murine) Energy Homeostasis Associated (ENHO) interaction partners

  1. our data suggest that adropin is a membrane-bound protein that interacts with the brain-specific (show CALY Proteins) Notch1 (show NOTCH1 Proteins) ligand NB3 (show CNTN6 Proteins).

  2. Release of adropin in the fed condition regulates fuel selection in skeletal muscle, promoting glucose oxidation over fat oxidation. The molecular mechanisms of adropin's effects involve acetylation (suggesting inhibition) of the transcriptional co-activator PGC1alpha, reducing PDK4 (show PDK4 Proteins) and CPT1B (show CPT1B Proteins) activity. Increased PGC1alpha acetylation by adropin may be mediated by inhibiting Sirtuin-1 (SIRT1 (show SIRT1 Proteins)), a PGC1alpha deacetylase.

  3. Adropin has an endothelial protective function mediated via upregulation of eNOS (show NOS3 Proteins) expression through the VEGFR2 (show KDR Proteins)-PI3K-Akt (show AKT1 Proteins) and VEGFR2 (show KDR Proteins)-ERK1/2 pathways. Adropin therapy may thus be useful for limiting diseases characterized by endothelial dysfunction.

  4. Adropin is the name given to the secreted peptide encoded by human C9orf165. In mice, it is abundant in liver where it is regulated by dietary macronutrients. Adropin regulates expression of genes involved in lipogenesis and adipogenesis.

Human Energy Homeostasis Associated (ENHO) interaction partners

  1. Serum adropin concentrations are negatively associated with renal function.

  2. High adropin expression is associated with polycystic ovary syndrome.

  3. There were no significant differences among the groups of systemic sclerosis (SSc (show CYP11A1 Proteins)) and controls in terms of ENHO gene expressions. There was no significant difference between the limited and diffuse cutaneous subtypes of SSc (show CYP11A1 Proteins) in terms of serum adropin level and ENHO gene expression. Moreover, serum adropin level and ENHO gene expression were not associated with the disease activity and severity indexes.

  4. Enho mutations plays a critical role in activating endothelial cells during neutrophil recruitment and neutrophil-endothelium cell interactions under IL-1 (show IL1A Proteins) and TNF-alpha (show TNF Proteins)-induced vascular inflammation and increases susceptibility to MPOANCA associated lung injury.

  5. In HD patients, lower plasma adropin concentration is associated with dyslipidemia. Major homozygosity of RXRA (show RXRA Proteins) seems to have an opposite effect on plasma adropin compared with that of ENHO rs2281997

  6. Data suggest that serum adropin (ENHO) levels in normal, overweight, and obese adults negatively correlate with vascular stiffness (using common carotid artery) and adiposity (using abdominal visceral fat), and positively correlate with plasma nitric oxide levels (using nitrite/nitrate) and cardiorespiratory fitness; aerobic exercise training up-regulates serum adropin.

  7. The adropin levels of metabolic syndrome, obesity, and control groups also showed no difference

  8. Circulating adropin levels were determined lower in patients with endometrial cancer than in a control group.

  9. Lipids originating either from the diet or from endogenous production appear to positively affect plasma adropin concentrations in humans.

  10. Serum adropin levels were significantly lower in obese children; however, there was no correlation between serum adropin levels and blood pressure variables.

Energy Homeostasis Associated (ENHO) Protein Profile

Protein Summary

Involved in the regulation of glucose homestasis and lipid metabolism (By similarity).

Gene names and symbols associated with ENHO

  • energy homeostasis associated (Enho)
  • energy homeostasis associated (ENHO)
  • adropin (LOC100342418)
  • 1110065P19Rik protein
  • 2310040A07Rik protein
  • C8H9orf165 protein
  • C9orf165 protein
  • UNQ470 protein

Protein level used designations for ENHO

adropin , energy homeostasis-associated protein , energy homeostasis associated , GAAI470 , energy homeostasis associated protein

500443 Mus musculus
701072 Macaca mulatta
100342418 Oryctolagus cuniculus
375704 Homo sapiens
783487 Bos taurus
69638 Mus musculus
100303726 Sus scrofa
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