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Ets Variant 4 (ETV4) ELISA Kits

Transcriptional activator that binds to the enhancer of the adenovirus E1A gene\; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.. Additionally we are shipping ETV4 Antibodies (73) and ETV4 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ETV4 2118 P43268
Anti-Rat ETV4 ETV4 360635  
Anti-Mouse ETV4 ETV4 18612  
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More ELISA Kits for ETV4 Interaction Partners

Human Ets Variant 4 (ETV4) interaction partners

  1. NCOA2ETV4 protein would contain the helixloophelix, PAS_9 and PAS_11, CITED domains, the SRC1 (show SRC ELISA Kits) domain of NCOA2 (show NCOA2 ELISA Kits) and the ETS (show ETS1 ELISA Kits) DNAbinding domain of ETV4.

  2. PEA3-subgroup transcription factors are key players of the Met signaling integration involved in regulation of migration and invasiveness of tumor cells.

  3. ACC1 (show ACACA ELISA Kits) and ACLY (show ACLY ELISA Kits) regulate the levels of ETV4 under hypoxia via increased alpha-ketoglutarate. These results reveal that the ACC1 (show ACACA ELISA Kits)/ACLY (show ACLY ELISA Kits)-alpha-ketoglutarate-ETV4 axis is a novel means by which metabolic states regulate transcriptional output

  4. ETV4 overexpression is associated with prostate cancer aggressiveness.

  5. molecular mechanism underlying DBC1 (show DBC1 ELISA Kits) function in PEA3-mediated transcription involves inhibition of SIRT1 (show SIRT1 ELISA Kits) interaction with PEA3 and of SIRT1 (show SIRT1 ELISA Kits)-mediated deacetylation of PEA3

  6. Implicate Pea3 as a mediator of liver metastases in colorectal cancer.

  7. Silencing of ETV4 suppresses invasion of prostate cancer cells by inhibiting the expression of uPA (show PRAP1 ELISA Kits)/uPAR (show PLAUR ELISA Kits) as well as (MMP)-2 (show MMP2 ELISA Kits) and MMP-9 (show MMP9 ELISA Kits)

  8. data suggest that polyomavirus enhancer activator 3 and epithelium-specific transcription factor-1 (show HNF1A ELISA Kits) may play important roles in pluri potent and tumorigenic embryonic carcinoma cells.

  9. developed a novel RNA in situ hybridization-based assay for the in situ detection of ETV1 (show ETV1 ELISA Kits), ETV4, and ETV5 in formalin-fixed paraffin-embedded tissues from prostate needle biopsies, prostatectomy, and metastatic PCa (show FLVCR1 ELISA Kits) specimens using RNA probes

  10. PEA3 regulates OCT4 (show POU5F1 ELISA Kits) gene expression as a transcriptional activator

Zebrafish Ets Variant 4 (ETV4) interaction partners

  1. etv5a and etv4 have roles in mediating epithelial cell fate during zebrafish kidney development

  2. Pea3 and erm are required for zebrafish pronephrogenesis and can functionally complement each other, and the wt1a gene may be one of their downstream targets.

  3. Overlapping functions of pea3 ETS (show ETS1 ELISA Kits) transcription factors in FGF signaling during zebrafish development are reported.

Mouse (Murine) Ets Variant 4 (ETV4) interaction partners

  1. ETS-related transcription factors ETV4 and ETV5 are involved in proliferation and induction of differentiation-associated genes in embryonic stem (ES) cells.

  2. paracrine signaling via fibroblast growth factor 2 (Fgf2 (show FGF2 ELISA Kits)) and Mapk (show MAPK1 ELISA Kits) between these diverged tumor subclones causes enhanced expression of the Pea3 transcription factor, resulting in metastatic dissemination of the neuroendocrine tumor subclones.

  3. Study hypothesized that PEA3 might play an essential role in the activation of the FAK (show PTK2 ELISA Kits) gene during tumor metastasis.

  4. Study reveals molecular insight into how the Ets (show ETS1 ELISA Kits) family transcription factor Pea3 favors EMT (show ITK ELISA Kits) and contributes to tumorigenesis via a negative regulatory loop with Cyclin D2 (show CCND2 ELISA Kits), a new Pea3 target gene.

  5. oncogenic Etv4 promotes prostate cancer metastasis in response to coactivation of PI3-kinase and Ras signaling pathways in a genetically engineered model of highly penetrant, metastatic prostate cancer

  6. PEA3-null fibroblasts exhibit impaired c-src activation and motility defects.

  7. Smad2 (show SMAD2 ELISA Kits) and PEA3 regulate RGC-32 (show C13orf15 ELISA Kits) transcription which is essential for smooth muscle cell differentiation from neural crest cells.

  8. study provides evidence for a protumorigenic role of PEA3 factors in breast neoplasia, and supports targeting the PEA3 transcription factor family in breast cancer

  9. Induction of Pea3 gene expression by peripheral signals is required to coordinate the central position and terminal arborization of specific sets of spinal motor neurons.

  10. PEA3 expression in developing motor neurons is regulated by GDNF (show GDNF ELISA Kits) signals from the limb bud.

ETV4 Antigen Profile

Antigen Summary

Transcriptional activator that binds to the enhancer of the adenovirus E1A gene\; the core-binding sequence is 5'GT-3'.

Gene names and symbols associated with Ets Variant 4 (ETV4) ELISA Kits

  • ets variant 4 (ETV4) antibody
  • ets variant gene 4 (E1A enhancer binding protein, E1AF) (ETV4) antibody
  • ets variant 4 (Etv4) antibody
  • ets variant gene 4 (etv4) antibody
  • ets variant gene 4 (E1A enhancer binding protein, E1AF) (Etv4) antibody
  • AW414408 antibody
  • E1A-F antibody
  • E1AF antibody
  • ETV4 antibody
  • Pea-3 antibody
  • pea3 antibody
  • PEAS3 antibody

Protein level used designations for Ets Variant 4 (ETV4) ELISA Kits

ets variant 4 , ETS translocation variant gene 4 , ets variant gene 4 (E1A enhancer binding protein, E1AF) , ets domain protein , ETS translocation variant 4 , EWS protein/E1A enhancer binding protein chimera , adenovirus E1A enhancer-binding protein , ets variant gene 4 (E1A enhancer-binding protein, E1AF) , polyomavirus enhancer activator 3 homolog , ETS translocation variant 4-like , polyomavirus enhancer activator-3 , ETS domain-containing transcription factor PEA3 , ETS-domain transcription factor pea3 , etID309954.12 , ETS variant protein 4 , POLYOMAVIRUS ENHANCER ACTIVATOR 3 (PEA3 PROTEIN) (ETS TRANSLOCATION VARIANT 4)

281149 Bos taurus
395747 Gallus gallus
454715 Pan troglodytes
100065121 Equus caballus
2118 Homo sapiens
533129 Bos taurus
360635 Rattus norvegicus
403641 Canis lupus familiaris
30700 Danio rerio
18612 Mus musculus
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