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Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.. Additionally we are shipping ETV5 Antibodies (107) and many more products for this protein.
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MiR (show MLXIP Proteins)-200b inhibition by transfection in MCF-7 markedly decreased miR (show MLXIP Proteins)-200b level, elevated ERM expression, and enhanced cell migration and invasion. MiR (show MLXIP Proteins)-200b overexpression in MDA-MB-231 obviously increased miR (show MLXIP Proteins)-200b level, reduced ERM expression, and weakened cell migration and invasion.
Resistin (show RETN Proteins), a fat-derived secretory factor, promotes metastasis of MDA-MB-231 human breast cancer cells through ERM activation
ERM proteins contribute toward accelerated CD44 (show CD44 Proteins) shedding by MT1-MMP (show MMP14 Proteins) through ERM protein-mediated interactions between their cytoplasmic tails.
Our results reveal a novel ERM-based spatial mechanism that is coopted by DLBCL cells to sustain tumor cell growth and survival.
Increase of ETV5 protein expression is associated with endometrial cancer invasion.
developed a novel RNA in situ hybridization-based assay for the in situ detection of ETV1 (show ETV1 Proteins), ETV4 (show ETV4 Proteins), and ETV5 in formalin-fixed paraffin-embedded tissues from prostate needle biopsies, prostatectomy, and metastatic PCa (show FLVCR1 Proteins) specimens using RNA probes
Snail (show SNAI1 Proteins) regulates the motility and invasiveness of oral cancer cells via RhoA (show RHOA Proteins)/Cdc42 (show CDC42 Proteins)/p-ERM pathway.
there is a higher expression of ERM/ETV5 in early stages of endometrioid endometrial carcinomas
we found that the downregulation of ETV5 reduced the expression of the oncogenic transcription factor FOXM1 (show FOXM1 Proteins).
This data suggests that ETV5 has a significant role in regulating MMP2 (show MMP2 Proteins) expression and therefore matrix resorption in human chondrosarcoma, and thus may be a targetable upstream effector of the metastatic cascade in this cancer.
etv5a and etv4 (show ETV4 Proteins) have roles in mediating epithelial cell fate during zebrafish kidney development
Zebrafish etv5a is essential for the inhibition of ventral mesoderm cell proliferation and for the formation of the hemato-vascular lineage.
bioinformatic analysis, real-time PCR, and luciferase assay validated that AK015322 serves as a decoy of microRNA-19b-3p (miR (show MLXIP Proteins)-19b-3p), antagonizes its function, and attenuates the repression of its endogenous target transcriptional factor Ets-variant 5 (ETV5) which was a pivotal gene for spermatogonial stem cell self-renewal
Further investigations identified Pak1 (show PAK1 Proteins)-ERM as a downstream signaling cascade upon Rac1 activation in the luminal epithelium necessary for uterine receptivity...Rac1 via P38 MAPK (show MAPK14 Proteins) signaling ensures timely epithelial apoptotic death at postimplantation.
The data of this study suggested that the obesity-associated transcription factor ETV5 normally acts to diminish circulating glucocorticoids.
ETS-related transcription factors ETV4 (show ETV4 Proteins) and ETV5 are involved in proliferation and induction of differentiation-associated genes in embryonic stem (ES) cells.
Noise-decreased levels of ROCK2 results in reduction of phosphorylation of ERM that leads to depolymerization of actin filaments
The transcription factors Etv5 and STAt3 (show STAT3 Proteins) control TH17 cell development and allergic airway inflammation.
A missense mutation in the transcription factor ETV5 leads to sterility, increased embryonic and perinatal death, postnatal growth restriction, renal asymmetry and polydactyly in the mouse.
Mouse germline stem (GS) cell transfected with an activated form of Map2k1 (show MAP2K1 Proteins) have upregulated Etv5 and Bcl6b (show BCL6B Proteins) gene expression.
found to be a critical downstream regulator of glial cell line-derived neurotrophic factor (show GDNF Proteins)-signaling that mediated the expression of several known spermatogonial stem cell self-renewal related genes
Results suggest that Etv5 is important for the developmental competence of germ cells and the regulation of responses to steroid hormones in female mice.
Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.
ETS translocation variant 5
, ets-related molecule
, ets-related protein ERM
, ets variant gene 5 (ets-related molecule)
, ets domain protein