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Fat Mass and Obesity-Associated (FTO) ELISA Kits

FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of FTO is not known. Additionally we are shipping FTO Antibodies (125) and FTO Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FTO 79068 Q9C0B1
FTO 26383 Q8BGW1
FTO 291905 Q2A121
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Top FTO ELISA Kits at

Showing 4 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.156-10 ng/mL 100 Tests Log in to see 2 to 3 Days
0.156-10 ng/mL 100 Tests Log in to see 2 to 3 Days
0.156-10 ng/mL   96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 16 to 21 Days

More ELISA Kits for FTO Interaction Partners

Human Fat Mass and Obesity-Associated (FTO) interaction partners

  1. The present study suggested that GSTM1 (show GSTM1 ELISA Kits), GSTT1 (show GSTT1 ELISA Kits) and FTO gene polymorphisms are associated with increased risk for cataract in North Indian populations.

  2. Risk analysis of the rs8057044 polymorphism of the FTO gene revealed individuals with GA and GG genotypes to have 1.112 and 1.731 times higher risks of developing metabolic syndrome ( MS) than those with the AA genotype, respectively

  3. data showed that the rs9939609 FTO gene polymorphism is not a useful genetic test prior to laparoscopic sleeve gastrectomy to help clinicians predicting the weight loss for severely obese patients in short-term follow-up.

  4. The A-allele frequencies (95% CI) of FTO polymorphisms rs8050136 and rs9939609 were 39% (34-44%); 38% (33-43%) and 40% (35-45%); 41% (36-46%), respectively.

  5. The effects of exercise combined with dietary intervention on obesity were associated with the FTO rs9939609 polymorphism in Chinese adolescents and children.

  6. Individuals carrying the homozygous FTO obesity-predisposing allele may lose more weight through diet/lifestyle interventions than noncarriers. [Review, Meta-analysis]

  7. data suggest that FTO SNPs make differential contributions to obesity risk and support the hypothesis that gender differences in the mechanisms involving these variants may contribute to disease development

  8. There is a different evolution of weight loss in obese carriers of the FTO gene variant rs9939609 after bariatric surgery...evident at only 2 y postbariatric surgery, inducing a lower proportion of surgery success and a greater and earlier weight regain.

  9. The young Polish population is characterized by two disparate haplotypes of common FTO gene variants: TCGA (a risk SNP haplotype), and CTAT (a protective haplotype) in terms of body fat distribution.

  10. FTO rs9939609 associated with aortic valve stenosis in German men. Heterozygotes had a significantly lower chance to develop AVS. This was independent of BMI and other variables such as diabetes mellitus.

Mouse (Murine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. These results reveal that FTO regulates fatty acid mobilization in adipocytes and thus body weight in part through posttranscriptional regulation of Angptl4 (show ANGPTL4 ELISA Kits).

  2. FTO-dependent N6-methyladenosine demethylation may be affected by betaine.

  3. FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1 (show ARNTL ELISA Kits)-induced transcription.

  4. FTO expression and N6-methyladenosine levels are inversely correlated during adipogenesis. FTO depletion blocks differentiation and only catalytically active FTO restores adipogenesis.

  5. FTO is present in both the nucleus and cytoplasm, with a mobile fraction that shuttles between both cellular compartments, possibly by interaction with XPO2 (show CSE1L ELISA Kits).

  6. FTO plays an important role in the development of metabolic disorders and is an interesting target for therapeutic agents.

  7. data suggest that IRX3 (show IRX3 ELISA Kits) is a functional long-range target of obesity-associated variants within FTO and represents a novel determinant of body mass and composition

  8. FTO silencing did not modify PPARgamma2 (show PPARG ELISA Kits) mRNA levels. Partial reduction of FTO did not influence the first step of 3T3-L1 adipocyte differentiation.

  9. Downregulation was seen only with essential amino-acid deficiency and not with non-essential amino acids. These data suggest that FTO might have a role in the sensing of essential amino-acid availability.

  10. Data suggest that Fto-deficient white adipocytes exhibit some metabolic functions similar to brown adipocytes; expression of Ucp1 (uncoupling protein-1 (show UCP1 ELISA Kits)) is up-regulated and mitochondrial uncoupling is increased in Fto-deficient adipocytes.

Pig (Porcine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. In this study, the authors characterise the nucleotide variability and haplotype diversity of the porcine fat mass and obesity-associated (FTO) gene in breeds having different predispositions to fat deposition traits.

  2. In pig, the FTO gene influences back fat depth in the commercial populations.

  3. This study will provide clues for obtaining a better understanding of the porcine FTO gene function.

  4. The results of the association analyses confirmed the effect of the FTO mutation on obesity-related traits in the Italian Duroc pigs (P < 0.01) and in the commercial pigs.

  5. The porcine fat mass and obesity associated (FTO) gene is associated with fat deposition in Italian Duroc pigs.

Cow (Bovine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. 34 FTO polymorphisms revealed significant association of FTO variants with lean meat percentage in Simmental and Brown cattle breeds.

  2. association signals not only provided evidence for at least two causative mutations in the FTO locus with a functional effect on milk but also milk protein (show CSN2 ELISA Kits) yield

  3. Haplotype frequencies and linkage disequilibrium (LD) coefficients of FTO single nucleotide polymorphisms in three Chinese indigenous cattle breeds were analyzed.

FTO Antigen Profile

Antigen Summary

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Gene names and symbols associated with FTO

  • fat mass and obesity associated (FTO) antibody
  • fat mass and obesity associated (Fto) antibody
  • fat mass and obesity associated (fto) antibody
  • AW743446 antibody
  • mKIAA1752 antibody
  • RGD1305121 antibody

Protein level used designations for FTO

alpha-ketoglutarate-dependent dioxygenase FTO , fat mass and obesity-associated protein , protein fto , protein fatso , fat mass and obesity associated protein , Protein fatso

79068 Homo sapiens
26383 Mus musculus
478125 Canis lupus familiaris
100127165 Sus scrofa
291905 Rattus norvegicus
100060565 Equus caballus
618622 Bos taurus
100125353 Ovis aries
447305 Xenopus laevis
100173222 Pongo abelii
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