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Fat Mass and Obesity-Associated (FTO) ELISA Kits

FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of FTO is not known. Additionally we are shipping FTO Antibodies (145) and FTO Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FTO 79068 Q9C0B1
FTO 26383 Q8BGW1
FTO 291905 Q2A121
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Top FTO ELISA Kits at antibodies-online.com

Showing 3 out of 9 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 50 pg/mL 0.156-10 ng/mL 96 Tests Log in to see 2 to 3 Days
$951.50
Details
Mouse 0.156-10 ng/mL 1 kit Log in to see 9 Days
$1,491.43
Details
Rat
0.156-10 ng/mL 96 Tests Log in to see 11 to 13 Days
$946.00
Details

More ELISA Kits for FTO Interaction Partners

Human Fat Mass and Obesity-Associated (FTO) interaction partners

  1. Case Report: MC4R p.Met215del coexisting with FTO and MC1R gene variants, causes severe early onset obesity.

  2. The FTO rs9939609 polymorphism was associated with anthropometric parameters and metabolic syndrome in the younger age group (25-44 years) and in individuals having low level of physical activity.

  3. No significant association between FTO gene polymorphisms and coronary artery disease in type 2 diabetic Iranian patients.

  4. Due to lack of replication regarding FTO association with obesity in the Greek adult population, study analyzed 3 SNPs, i.e. rs9939609, rs9930506 and rs3751812 in a cohort of 203 adults, comprising of 95 obese, 58 overweight and 50 control individuals. Analysis has shown a significant association for FTO (rs9930506; A/G) 'G' allele with obesity and a difference by 3.2 BMI units between homozygote AA versus GG.

  5. The data revealed that the FTO rs9939609 SNP exhibited a significant association with obesity in Taiwanese patients.

  6. carriage of the FTO minor allele was not associated with differential change in adiposity after weight loss interventions. These findings show that individuals carrying the minor allele respond equally well to dietary, physical activity, or drug based weight loss interventions and thus genetic predisposition to obesity associated with the FTO minor allele can be at least partly counteracted through such interventions.

  7. An SNP in the FTO (rs9939609) gene but not in the MC4R (show MC4R ELISA Kits) (rs17782313) gene was significantly associated with prepregnancy body mass index (BMI) >/=25 kg/m(2) (relative riskFTO = 2.1; 95% confidence interval [CI], 1.4-3.1). SNPs were not statistically associated with excessive gestational weight gain (GWG) or postpartum weight retention (PPWR).

  8. genetic association studies in population in Spain: Data suggest that an SNP in FTO (rs9939609) is associated with insulin (show INS ELISA Kits) resistance (IR) and hyperlipidemia; in the population studied, maternal FTO polymorphism affects in an opposite manner than neonatal FTO the IR and cardiovascular disease markers in term, normo-weight, appropriate-for-gestational-age neonates.

  9. Our findings demonstrate that ENPP1 (show ENPP1 ELISA Kits), TCF7L2 (show TCF7L2 ELISA Kits), and FTO may predispose to T2DM in the mixed-ancestry population.

  10. FTO rs9939609, MC4R (show MC4R ELISA Kits) rs17782313, and PPARgamma (show PPARG ELISA Kits) rs1801282 polymorphisms seem to have little effect on the incidence of metabolic malfunctions and no effect on androgen-related disorders in the examined middle-aged and elderly men.

Mouse (Murine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. Fto deficiency affects the gene and miR130/miR378 expression involved in brown adipogenesis and browning of white adipose tissue in mice.

  2. Here we show that FTO expression is increased after ureteral obstruction and renal fibrosis.

  3. Taken together, the results suggest that Fto regulates the proliferation and differentiation of 3T3-L1 cells via multiple mechanisms, including PPARgamma (show PPARG ELISA Kits) and PI3K/Akt (show AKT1 ELISA Kits) signaling.

  4. These results reveal that FTO regulates fatty acid mobilization in adipocytes and thus body weight in part through posttranscriptional regulation of Angptl4 (show ANGPTL4 ELISA Kits).

  5. FTO-dependent N6-methyladenosine demethylation may be affected by betaine.

  6. FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1 (show ARNTL ELISA Kits)-induced transcription.

  7. FTO expression and N6-methyladenosine levels are inversely correlated during adipogenesis. FTO depletion blocks differentiation and only catalytically active FTO restores adipogenesis.

  8. FTO is present in both the nucleus and cytoplasm, with a mobile fraction that shuttles between both cellular compartments, possibly by interaction with XPO2 (show CSE1L ELISA Kits).

  9. FTO plays an important role in the development of metabolic disorders and is an interesting target for therapeutic agents.

  10. data suggest that IRX3 (show IRX3 ELISA Kits) is a functional long-range target of obesity-associated variants within FTO and represents a novel determinant of body mass and composition

Pig (Porcine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. In this study, the authors characterise the nucleotide variability and haplotype diversity of the porcine fat mass and obesity-associated (FTO) gene in breeds having different predispositions to fat deposition traits.

  2. In pig, the FTO gene influences back fat depth in the commercial populations.

  3. This study will provide clues for obtaining a better understanding of the porcine FTO gene function.

  4. The results of the association analyses confirmed the effect of the FTO mutation on obesity-related traits in the Italian Duroc pigs (P < 0.01) and in the commercial pigs.

  5. The porcine fat mass and obesity associated (FTO) gene is associated with fat deposition in Italian Duroc pigs.

Cow (Bovine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. 34 FTO polymorphisms revealed significant association of FTO variants with lean meat percentage in Simmental and Brown cattle breeds.

  2. association signals not only provided evidence for at least two causative mutations in the FTO locus with a functional effect on milk but also milk protein (show CSN2 ELISA Kits) yield

  3. Haplotype frequencies and linkage disequilibrium (LD) coefficients of FTO single nucleotide polymorphisms in three Chinese indigenous cattle breeds were analyzed.

FTO Antigen Profile

Antigen Summary

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Gene names and symbols associated with FTO

  • fat mass and obesity associated (FTO) antibody
  • fat mass and obesity associated (Fto) antibody
  • fat mass and obesity associated (fto) antibody
  • AW743446 antibody
  • mKIAA1752 antibody
  • RGD1305121 antibody

Protein level used designations for FTO

alpha-ketoglutarate-dependent dioxygenase FTO , fat mass and obesity-associated protein , protein fto , protein fatso , fat mass and obesity associated protein , Protein fatso

GENE ID SPECIES
79068 Homo sapiens
26383 Mus musculus
478125 Canis lupus familiaris
100127165 Sus scrofa
291905 Rattus norvegicus
100060565 Equus caballus
618622 Bos taurus
100125353 Ovis aries
447305 Xenopus laevis
100173222 Pongo abelii
Selected quality suppliers for FTO (FTO) ELISA Kits
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