Fat Mass and Obesity-Associated (FTO) ELISA Kits

FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of FTO is not known. Additionally we are shipping FTO Antibodies (136) and FTO Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FTO 79068 Q9C0B1
FTO 26383 Q8BGW1
FTO 291905 Q2A121
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Top FTO ELISA Kits at antibodies-online.com

Showing 3 out of 8 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 50 pg/mL 0.156-10 ng/mL 96 Tests Log in to see 2 to 3 Days
Mouse 20 pg/mL 0.156-10 ng/mL 96 Tests Log in to see 6 to 8 Days
Rat 0.156-10 ng/mL 96 Tests Log in to see 15 to 18 Days

More ELISA Kits for FTO Interaction Partners

Human Fat Mass and Obesity-Associated (FTO) interaction partners

  1. the FTO rs9939609 SNP was found to influence the relationship between these variables, as an association between disorder of corporeality and emotional eating was found only in A-allele carriers. A-allele seems to represent a potential additive risk factor for EDs persons, with bodily disorders to develop emotional eating and binge eating behaviors.

  2. The FTO gene polymorphisms rs9939609 and rs17817449 play a role in the in the development of insulin (show INS ELISA Kits) resistance and hence occurrence of type 2 dabetes mellitus in obese patients.

  3. Study found that in a Korean cohort, the FTO rs9939609 polymorphism is an independent risk factor for obesity and also for biological aging in the nonobese population.

  4. Genetic clues to the mechanism by which MC4R, FTO, and NMB influences changes in BMI and obesity.

  5. BDNF (show BDNF ELISA Kits) rs2030323 is associated with 100 to 150 greater total caloric intake per allele, with additional contributions of MC4R (show MC4R ELISA Kits) and, in non-Hispanic white individuals, FTO.

  6. FTO and FABP2 (show FABP2 ELISA Kits) gene polymorphisms were significantly associated with susceptibility to metabolic syndrome and obesity in this cohort.

  7. FTO variant rs9939609 associates with obesity, correlates with anthropometric traits and plasma lipid profile in subjects from Pakistan.

  8. FTO obesity risk variants are linked to IRX3 expression and adipocyte size in lean children.

  9. For only the children with two high-risk alleles in FTO, parental restriction was positively associated with child BMI-percentile

  10. There is an association between the AA genotype of rs9939609 (FTO) polymorphism and BMI among schoolchildren. The association between overweight/obesity in schoolchildren with a family history of obesity was found mainly among students with the AA genotype.

Mouse (Murine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. FTO may have a deleterious role in hepatic cells during lipotoxic conditions, and up-regulation of FTO may contribute to the increased liver damage in non-alcoholic steatohepatitis

  2. Fto deficiency affects the gene and miR130/miR378 expression involved in brown adipogenesis and browning of white adipose tissue in mice.

  3. Here we show that FTO expression is increased after ureteral obstruction and renal fibrosis.

  4. Taken together, the results suggest that Fto regulates the proliferation and differentiation of 3T3-L1 cells via multiple mechanisms, including PPARgamma (show PPARG ELISA Kits) and PI3K/Akt (show AKT1 ELISA Kits) signaling.

  5. These results reveal that FTO regulates fatty acid mobilization in adipocytes and thus body weight in part through posttranscriptional regulation of Angptl4 (show ANGPTL4 ELISA Kits).

  6. FTO-dependent N6-methyladenosine demethylation may be affected by betaine.

  7. FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1 (show ARNTL ELISA Kits)-induced transcription.

  8. FTO expression and N6-methyladenosine levels are inversely correlated during adipogenesis. FTO depletion blocks differentiation and only catalytically active FTO restores adipogenesis.

  9. FTO is present in both the nucleus and cytoplasm, with a mobile fraction that shuttles between both cellular compartments, possibly by interaction with XPO2 (show CSE1L ELISA Kits).

  10. FTO plays an important role in the development of metabolic disorders and is an interesting target for therapeutic agents.

Pig (Porcine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. In this study, the authors characterise the nucleotide variability and haplotype diversity of the porcine fat mass and obesity-associated (FTO) gene in breeds having different predispositions to fat deposition traits.

  2. In pig, the FTO gene influences back fat depth in the commercial populations.

  3. This study will provide clues for obtaining a better understanding of the porcine FTO gene function.

  4. The results of the association analyses confirmed the effect of the FTO mutation on obesity-related traits in the Italian Duroc pigs (P < 0.01) and in the commercial pigs.

  5. The porcine fat mass and obesity associated (FTO) gene is associated with fat deposition in Italian Duroc pigs.

Cow (Bovine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. 34 FTO polymorphisms revealed significant association of FTO variants with lean meat percentage in Simmental and Brown cattle breeds.

  2. association signals not only provided evidence for at least two causative mutations in the FTO locus with a functional effect on milk but also milk protein (show CSN2 ELISA Kits) yield

  3. Haplotype frequencies and linkage disequilibrium (LD) coefficients of FTO single nucleotide polymorphisms in three Chinese indigenous cattle breeds were analyzed.

FTO Antigen Profile

Antigen Summary

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Gene names and symbols associated with FTO

  • fat mass and obesity associated (FTO) antibody
  • fat mass and obesity associated (Fto) antibody
  • fat mass and obesity associated (fto) antibody
  • AW743446 antibody
  • mKIAA1752 antibody
  • RGD1305121 antibody

Protein level used designations for FTO

alpha-ketoglutarate-dependent dioxygenase FTO , fat mass and obesity-associated protein , protein fto , protein fatso , fat mass and obesity associated protein , Protein fatso

79068 Homo sapiens
26383 Mus musculus
478125 Canis lupus familiaris
100127165 Sus scrofa
291905 Rattus norvegicus
100060565 Equus caballus
618622 Bos taurus
100125353 Ovis aries
447305 Xenopus laevis
100173222 Pongo abelii
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