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Fat Mass and Obesity-Associated (FTO) ELISA Kits

FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of FTO is not known. Additionally we are shipping FTO Antibodies (139) and FTO Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FTO 79068 Q9C0B1
FTO 26383 Q8BGW1
FTO 291905 Q2A121
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Top FTO ELISA Kits at antibodies-online.com

Showing 3 out of 7 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 50 pg/mL 0.156-10 ng/mL 96 Tests Log in to see 2 to 3 Days
$951.50
Details
Mouse 20 pg/mL 0.156-10 ng/mL 96 Tests Log in to see 6 to 8 Days
$951.50
Details
Rat 0.156-10 ng/mL 96 Tests Log in to see 11 to 13 Days
$946.00
Details

More ELISA Kits for FTO Interaction Partners

Human Fat Mass and Obesity-Associated (FTO) interaction partners

  1. The maternal and infant AA genotype of the obesity associated FTO rs9939609 SNP associates with increased risk for gestational age pregnancy (SGA), and spontaneous preterm birth (sPTB (show SPTB ELISA Kits))

  2. FTO rs9939609 variant is associated with the risk of pulmonary tuberculosis.

  3. This is the first report showing evidence of FTO and ABCA1 (show ABCA1 ELISA Kits) gene variant interactions affecting BMI, which may explain previously reported population differences

  4. FTO enhances leukemic oncogene (show RAB1A ELISA Kits)-mediated cell transformation and leukemogenesis, and inhibits all-trans-retinoic acid (ATRA)-induced AML (show RUNX1 ELISA Kits) cell differentiation, through regulating expression of targets such as ASB2 (show ASB2 ELISA Kits) and RARA (show RARA ELISA Kits) by reducing m(6)A levels in these mRNA transcripts.

  5. We find robust evidence of interaction with physical activity for the strongest known obesity risk-locus in the FTO gene, of which the body mass index-increasing effect is attenuated by ~30% in physically active individuals compared to inactive individuals.

  6. FTO may have a deleterious role in hepatic cells during lipotoxic conditions, and up-regulation of FTO may contribute to the increased liver damage in non-alcoholic steatohepatitis

  7. An FTO genetic variant was found to be associated with reduced semen quality.

  8. We confirmed associations with papillary thyroid cancer and SNPs in FOXE1 (show FOXE1 ELISA Kits)/HEMGN (show HEMGN ELISA Kits), SERPINA5 (show SERPINA5 ELISA Kits) (rs2069974), FTO (rs8047395), EVPL (show EVPL ELISA Kits) (rs2071194), TICAM1 (show TICAM1 ELISA Kits) (rs8120) and SCARB1 (show SCARB1 ELISA Kits) (rs11057820) genes. We found associations with SNPs in FOXE1 (show FOXE1 ELISA Kits), SERPINA5 (show SERPINA5 ELISA Kits), FTO, TICAM1 (show TICAM1 ELISA Kits) and HSPA6 (show HSPA6 ELISA Kits) and and follicular thyroid cancer

  9. the association between FTO and obesity appears to be due to its influence on expression of IRX3 [Figure 1]. Genetic studies indicated FTO as an important gene for obesity risk in various populations but the recent developments suggest that obesity-associated FTO SNPs have long-range interactions with IRX3.

  10. This study shows that FTO rs9939506 GG genotype is related to higher BMI and is associated with obesity in Polish adults.

Mouse (Murine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. FTO may have a deleterious role in hepatic cells during lipotoxic conditions, and up-regulation of FTO may contribute to the increased liver damage in non-alcoholic steatohepatitis

  2. Fto deficiency affects the gene and miR130/miR378 expression involved in brown adipogenesis and browning of white adipose tissue in mice.

  3. Here we show that FTO expression is increased after ureteral obstruction and renal fibrosis.

  4. Taken together, the results suggest that Fto regulates the proliferation and differentiation of 3T3-L1 cells via multiple mechanisms, including PPARgamma (show PPARG ELISA Kits) and PI3K/Akt (show AKT1 ELISA Kits) signaling.

  5. These results reveal that FTO regulates fatty acid mobilization in adipocytes and thus body weight in part through posttranscriptional regulation of Angptl4 (show ANGPTL4 ELISA Kits).

  6. FTO-dependent N6-methyladenosine demethylation may be affected by betaine.

  7. FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1 (show ARNTL ELISA Kits)-induced transcription.

  8. FTO expression and N6-methyladenosine levels are inversely correlated during adipogenesis. FTO depletion blocks differentiation and only catalytically active FTO restores adipogenesis.

  9. FTO is present in both the nucleus and cytoplasm, with a mobile fraction that shuttles between both cellular compartments, possibly by interaction with XPO2 (show CSE1L ELISA Kits).

  10. FTO plays an important role in the development of metabolic disorders and is an interesting target for therapeutic agents.

Pig (Porcine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. In this study, the authors characterise the nucleotide variability and haplotype diversity of the porcine fat mass and obesity-associated (FTO) gene in breeds having different predispositions to fat deposition traits.

  2. In pig, the FTO gene influences back fat depth in the commercial populations.

  3. This study will provide clues for obtaining a better understanding of the porcine FTO gene function.

  4. The results of the association analyses confirmed the effect of the FTO mutation on obesity-related traits in the Italian Duroc pigs (P < 0.01) and in the commercial pigs.

  5. The porcine fat mass and obesity associated (FTO) gene is associated with fat deposition in Italian Duroc pigs.

Cow (Bovine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. 34 FTO polymorphisms revealed significant association of FTO variants with lean meat percentage in Simmental and Brown cattle breeds.

  2. association signals not only provided evidence for at least two causative mutations in the FTO locus with a functional effect on milk but also milk protein (show CSN2 ELISA Kits) yield

  3. Haplotype frequencies and linkage disequilibrium (LD) coefficients of FTO single nucleotide polymorphisms in three Chinese indigenous cattle breeds were analyzed.

FTO Antigen Profile

Antigen Summary

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Gene names and symbols associated with FTO

  • fat mass and obesity associated (FTO) antibody
  • fat mass and obesity associated (Fto) antibody
  • fat mass and obesity associated (fto) antibody
  • AW743446 antibody
  • mKIAA1752 antibody
  • RGD1305121 antibody

Protein level used designations for FTO

alpha-ketoglutarate-dependent dioxygenase FTO , fat mass and obesity-associated protein , protein fto , protein fatso , fat mass and obesity associated protein , Protein fatso

GENE ID SPECIES
79068 Homo sapiens
26383 Mus musculus
478125 Canis lupus familiaris
100127165 Sus scrofa
291905 Rattus norvegicus
100060565 Equus caballus
618622 Bos taurus
100125353 Ovis aries
447305 Xenopus laevis
100173222 Pongo abelii
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