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Flightless I Homolog (Drosophila) (FLII) ELISA Kits

FLII encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. Additionally we are shipping Flightless I Homolog (Drosophila) Antibodies (30) and Flightless I Homolog (Drosophila) Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FLII 2314 Q13045
Anti-Mouse FLII FLII 14248 Q9JJ28
Anti-Rat FLII FLII 287375  
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Top Flightless I Homolog (Drosophila) ELISA Kits at

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 29.2 pg/mL 78.13-5000 pg/mL 96 Tests Log in to see 9 to 11 Days

More ELISA Kits for Flightless I Homolog (Drosophila) Interaction Partners

Zebrafish Flightless I Homolog (Drosophila) (FLII) interaction partners

  1. Embryos defective in flightless I homolog (flii), which encodes for an actin-regulating protein, exhibit normal coilings at 24 hours post fertilization (hpf) that is followed by significantly slower burst swimming at 48 hpf.

Human Flightless I Homolog (Drosophila) (FLII) interaction partners

  1. These data suggest FLII as a key regulator of ERalpha-mediated transcription through its role in regulating chromatin accessibility for the binding of RNA Polymerase II and possibly other transcriptional coactivators.

  2. Flii is constitutively secreted from macrophages and fibroblasts and is present in human plasma.

  3. The mouse (Fli1 (show FLI1 ELISA Kits)) and human Fli1 (show FLI1 ELISA Kits) genes are similarly regulated by Ets (show ETS1 ELISA Kits) factors in T cells.

  4. Fli-I promotes the GTP-bound active Rho-mediated relief of the autoinhibition of Daam1 and mDia1. Thus, Fli-I is a novel positive regulator of Rho-induced linear actin assembly mediated by DRFs.

  5. These data suggest that Flightless-I may facilitate interaction of the p160 coactivator complex with other coactivators or coactivator complexes containing actin or actin-like proteins.

  6. The gene that was most reproducibly up-regulated by EWS (show EWSR1 ELISA Kits)/FLI was NR0B1 (show NR0B1 ELISA Kits).

  7. effect of FliI protein on actin remodelling is a vital part of cellular motility, contraction and adhesion. Exact signaling pathways and mechanisms underpinning FliI effects in wound healing are yet to be fully identified[review]

  8. These findings support a novel mechanism whereby cytosolic CaMK-II influences beta-catenin dependent gene expression through Fli-I.

  9. The interactions between MyD88 (show MYD88 ELISA Kits) and multiple positive and negative regulators LRRFIP2 (show LRRFIP2 ELISA Kits), FLAP-1 (show LRRFIP1 ELISA Kits), and Fliih are highly dynamic and time-course dependent in differentially regulating/modulating NF-kappa B (show NFKB1 ELISA Kits) signal transduction.

  10. These findings support the model that CISK phosphorylates FLII and activates nuclear receptor transcription and suggest a new cell survival signaling pathway mediated by PI 3 (show PI3 ELISA Kits)-kinase and CISK.

Mouse (Murine) Flightless I Homolog (Drosophila) (FLII) interaction partners

  1. P-Rex1 stimulates migration through enhancing the interaction between Rac1 and the actin-remodelling protein.

  2. Genes downstream from Flii, including TGF-beta1 (show TGFB1 ELISA Kits) and TGF-beta3 (show TGFB3 ELISA Kits), showed significantly altered expression confirming a functional effect of the Rhodamine-Flii small interfering RNA on gene expression

  3. FliI interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling in fibroblasts.

  4. FLII functions in PPARgamma (show PPARG ELISA Kits) activation as a molecular switch to repress transcriptional activity by interrupting formation of the PPARgamma (show PPARG ELISA Kits)/RXRalpha (show RXRA ELISA Kits) complex.

  5. LRRFIP2 (show LRRFIP2 ELISA Kits) inhibits NLRP3 (show NLRP3 ELISA Kits) inflammasome activation by recruiting the caspase-1 (show CASP1 ELISA Kits) inhibitor Flightless-I, thus outlining a new mechanism for negative regulation of NLRP3 (show NLRP3 ELISA Kits) inflammasome.

  6. increasing the level of Flii in diabetic mouse wounds led to increased TLR4 (show TLR4 ELISA Kits) and NF- kappa B (show NFKB1 ELISA Kits) production. Treatment of murine diabetic wounds with neutralising antibodies to Flii led to an improvement in healing with decreased expression of TLR4 (show TLR4 ELISA Kits)

  7. Using a mouse model of epidermolysis bullosa acquisita, the effect of "mopping up" Flii using Flii-neutralizing antibodies before, during, and after blister formation was determined.

  8. Flii is constitutively secreted from macrophages and fibroblasts and is present in human plasma.

  9. FliI regulates cell migration through its localization to focal adhesions and its ability to cap actin filaments, which collectively affect focal adhesion maturation.

  10. Data show that mice with elevated Flii expression exhibit impaired wound healing.

Caenorhabditis elegans (C. elegans) Flightless I Homolog (Drosophila) (FLII) interaction partners

  1. fli-1 plays an important role in regulating the actin-dependent events during C. elegans development.

  2. FLI-1 controls germ line morphogenesis and rachis organization

Flightless I Homolog (Drosophila) (FLII) Antigen Profile

Antigen Summary

This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17.

Gene names and symbols associated with FLII

  • flightless I homolog (Drosophila) (FLII) antibody
  • flightless I homolog (Drosophila) (flii) antibody
  • protein flightless-1 homolog (LOC100051793) antibody
  • protein flightless-1 homolog (LOC100398338) antibody
  • protein flightless-1 homolog (LOC100619473) antibody
  • protein flightless-1 homolog (LOC100640615) antibody
  • flightless 1 homolog (flii) antibody
  • flightless I homolog (Drosophila) (Flii) antibody
  • Protein FLI-1 (fli-1) antibody
  • 3632430F08Rik antibody
  • DKFZp459O043 antibody
  • FLI antibody
  • Fli1 antibody
  • flightless antibody
  • Fliih antibody
  • FLIL antibody
  • im:7141769 antibody

Protein level used designations for FLII

flightless I homolog (Drosophila) , flightless-I homolog , protein flightless-1 homolog

454486 Pan troglodytes
479521 Canis lupus familiaris
514446 Bos taurus
560281 Danio rerio
585336 Strongylocentrotus purpuratus
700471 Macaca mulatta
723252 Macaca mulatta
100051793 Equus caballus
100173989 Pongo abelii
100398338 Callithrix jacchus
100475330 Ailuropoda melanoleuca
100543687 Meleagris gallopavo
100553018 Anolis carolinensis
100600354 Nomascus leucogenys
100619473 Monodelphis domestica
100640615 Amphimedon queenslandica
444748 Xenopus laevis
416515 Gallus gallus
2314 Homo sapiens
14248 Mus musculus
287375 Rattus norvegicus
176215 Caenorhabditis elegans
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