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GATA Binding Protein 5 Proteins (GATA5)

The protein encoded by GATA5 is a transcription factor that contains two GATA-type zinc fingers. Additionally we are shipping GATA5 Antibodies (61) and GATA5 Kits (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GATA5 14464 P97489
Rat GATA5 GATA5 499951  
GATA5 140628 Q9BWX5
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Top GATA5 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,080.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,116.67
Details

GATA5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
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More Proteins for GATA Binding Protein 5 (GATA5) Interaction Partners

Mouse (Murine) GATA Binding Protein 5 (GATA5) interaction partners

  1. GATA5 is expressed in microvascular endothelial cells and its inactivation in mice leads to vascular endothelial dysfunction and hypertension.

  2. GATA (show QRSL1 Proteins) transcription factors are repressors of hedgehog (show SHH Proteins) signaling, and NKX3.2 (show NKX3-2 Proteins) maintains the ability of sclerotomal cells to express SHH (show SHH Proteins) transcriptional targets in the presence of BMP signals by repressing the induction of Gata4 (show GATA4 Proteins)/5/6

  3. Gata5 deficiency induces airway hyperresponsiveness, at least in part, by blunting apoE (show APOE Proteins) and increasing IL-13 (show IL13 Proteins) expression.

  4. Expression of Gata5 very efficiently promotes cardiomyocyte fate from murine embryonic stem cells.

  5. USF1 transactivates GATA5 expression by binding to the E-box in its promoter

  6. compound Gata4 (show GATA4 Proteins)/Gata5 and Gata5/Gata6 (show GATA6 Proteins) mutants die embryonically or perinatally due to severe congenital heart defects

  7. Results unravel a critical cell-autonomous role for endocardial Gata5 in aortic valve formation and identify GATA5 as a potential gene responsible for congenital heart disease in humans.

  8. These results demonstrate functional redundancy between Gata4 and Gata5 during cardiac development and implicate Gata5 as a candidate modifier gene for congenital heart disease.

  9. data reveal that transcription factor GATA5 is required for differentiation of cardiogenic precursors into endothelial endocardial cells

  10. collaboration between GATA-6 (show GATA6 Proteins) and GATA-4 (show GATA4 Proteins), or GATA-6 (show GATA6 Proteins) and GATA-5 which can substitute for GATA-4 (show GATA4 Proteins), is involved in the perception of differentiation cues by embryonic stem cells in their determination of endoderm lineage

Human GATA Binding Protein 5 (GATA5) interaction partners

  1. Evidence supporting a genetic basis includes the autosomal dominance of Bicuspid aortic valve inheritance patterns, and the identification of mutations in GATA binding protein 5 transcription factor.

  2. Transcriptomic analysis of human microvascular endothelial cells with GATA5 knockdown reveals that GATA5 affects several genes and pathways critical for endothelial function.

  3. This study firstly links GATA5 mutation to DCM, which provides novel insight into the molecular mechanisms of DCM, suggesting a potential molecular target for the prenatal prophylaxis and allele-specific treatment of DCM.

  4. Promoter hypermethylation is an important mechanism of the transcriptional inactivation of GATA5 in invasive ductal breast carcinoma.

  5. A combination of GATA5 and SFRP2 (show SFRP2 Proteins) methylation could be promising as a marker for the detection and diagnosis of colorectal cancers and adenomas.

  6. A new potentially pathogenic variant in GATA5 contributes to the development of bicuspid aortic valve syndrome.

  7. DSVs in the GATA5 gene promoter may increase the susceptibility to the development of VSD as a risk factor.

  8. Rare sequence variants, p.Gln3Arg and p.Leu233Pro, in GATA5 are associated with human bicuspid aortic valve.

  9. study provides genetic evidence on the association of GATA5 loss-of-function mutations with enhanced susceptibility to bicuspid aortic valve (BAV), providing novel insight into the molecular mechanism involved in human BAV

  10. Results of this study showed an association of somatic GATA5 mutations with TOF (show FEZF2 Proteins), providing further insight into the underlying molecular mechanism of TOF (show FEZF2 Proteins).

GATA5 Protein Profile

Protein Summary

The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.

Gene names and symbols associated with GATA Binding Protein 5 Proteins (GATA5)

  • GATA binding protein 5 (GATA5)
  • GATA binding protein 5 (gata5)
  • GATA binding protein 5 (LOC100225872)
  • GATA binding protein 5 (Gata5)
  • GATA-binding protein 5 (Gata-5)
  • bB379O24.1 protein
  • GATA-5 protein
  • GATA5 protein
  • GATAS protein
  • xGATA-5 protein
  • xGATA-5a protein
  • xGATA-5b protein
  • xGATA5 protein
  • xGATA5a protein
  • xGATA5b protein

Protein level used designations for GATA Binding Protein 5 Proteins (GATA5)

GATA binding protein 5 , GATA-binding factor 5 , GATA-binding protein 5 , Transcription factor GATA-5 (GATA binding factor-5) , transcription factor GATA-5 , GATA binding factor-5 , GATA-5 transcription factor

GENE ID SPECIES
458389 Pan troglodytes
496852 Xenopus (Silurana) tropicalis
100225872 Taeniopygia guttata
14464 Mus musculus
499951 Rattus norvegicus
140628 Homo sapiens
485961 Canis lupus familiaris
504784 Bos taurus
100719097 Cavia porcellus
396391 Gallus gallus
100820750 Ovis aries
58931 Rattus norvegicus
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