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anti-Glycine Receptor (GRD) Antibodies

GRD encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits.

list all antibodies Gene Name GeneID UniProt
GRD 2743 P48167
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Top anti-Glycine Receptor Antibodies at

Showing 5 out of 5 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Rat Rabbit Un-conjugated ELISA, IHC (fro), WB 0.1 mL Log in to see 2 to 6 Days
Human Rabbit Un-conjugated DB, IHC, WB 200 μg Log in to see 6 to 11 Days
Human Rabbit Un-conjugated WB Western blot of rat spinal cord showing specific immunolabeling of the... 200 μg Log in to see 10 to 11 Days
Rat Rabbit Un-conjugated WB Western blot analysis using Glycine receptor antibody on rat  spinal c... 10 applications Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IHC (fro), WB Western blots of rat spinal cord showing specific immunolabeling of th... 200 μg Log in to see 3 to 4 Days

GRD Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality

Rat (Rattus)

Mouse (Murine)

Top referenced anti-Glycine Receptor Antibodies

  1. Human Polyclonal GRD Primary Antibody for IHC (fro), WB - ABIN361432 : Beckstead, Phelan, Mihic: Antagonism of inhalant and volatile anesthetic enhancement of glycine receptor function. in The Journal of biological chemistry 2001 (PubMed)
    Show all 7 references for ABIN361432

  2. Rat (Rattus) Polyclonal GRD Primary Antibody for WB - ABIN306940 : Fischer, Kneussel, Tintrup, Haverkamp, Rauen, Betz, Wässle: Reduced synaptic clustering of GABA and glycine receptors in the retina of the gephyrin null mutant mouse. in The Journal of comparative neurology 2000 (PubMed)
    Show all 6 references for ABIN306940

More Antibodies against Glycine Receptor Interaction Partners

Human Glycine Receptor (GRD) interaction partners

  1. GLRA1 (show GLRA1 Antibodies) and GLRB (show GLRB Antibodies) mutations are responsible for abnormal startled reactions in humans. (Review)

  2. The N-terminal region of GABRA3 (show GABRA3 Antibodies) and the GlyR beta subunit (show POLG Antibodies) occupies the same binding site of gephyrin (show GPHN Antibodies).

  3. We report novel GLRB (show GLRB Antibodies) mutations in hyperekplexia

  4. Systematic DNA sequencing of GLRB (show GLRB Antibodies) in individuals with hyperekplexia revealed new missense mutations in GLRB (show GLRB Antibodies), resulting in M177R, L285R and W310C substitutions.

  5. This study describes the definitive assignment of GLRB (show GLRB Antibodies) as the third major gene for hyperekplexia and impacts on the genetic stratification and biological causation of this neonatal/paediatric disorder.

  6. investigated neural progenitor cells in respect to their glycine receptor (show GLRB Antibodies) function and subunit expression using electrophysiology, calcium imaging, immunocytochemistry, and quantitative real-time PCR

  7. Distinct properties of glycine receptor beta (show GLRB Antibodies)+/alpha- interface: unambiguously characterizing heteromeric interface reconstituted in homomeric protein.

  8. This study presents a large family with Hereditary hyperekplexia (HH) as a result of homozygous mutation in GLRB (show GLRB Antibodies).

  9. Hereditary hyperekplexia-causing mutations that modify alpha1 beta GlyR channel function are almost exclusively located in the alpha1 to the exclusion of the beta subunit (show POLG Antibodies).

  10. The authors have identified a protein kinase C (PKC (show PKC Antibodies)) phosphorylation site within the cytoplasmic domain of the beta-subunit (show POLG Antibodies) of the GlyR (residue S403) that causes a reduction of the binding affinity between the receptor and gephyrin (show GPHN Antibodies).

Glycine Receptor (GRD) Antigen Profile

Protein Summary

This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Glycine Receptor (GRD) Antibodies

  • glycine receptor, beta (GLRB) antibody
  • HKPX2 antibody

Protein level used designations for anti-Glycine Receptor (GRD) Antibodies

glycine receptor 58 kDa subunit , glycine receptor subunit beta , glycine receptor, beta subunit

2743 Homo sapiens
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