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Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) ELISA Kits

HSPA9 encodes a member of the heat shock protein 70 gene family. Additionally we are shipping HSPA9 Antibodies (161) and HSPA9 Proteins (17) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human HSPA9 HSPA9 3313 P38646
Anti-Mouse HSPA9 HSPA9 15526 P38647
Anti-Rat HSPA9 HSPA9 291671  
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More ELISA Kits for HSPA9 Interaction Partners

Human Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. Biallelic mutations in HSPA9 are associated with the EVEN-PLUS syndrome of congenital malformations and skeletal dysplasia.

  2. veratridine enhances transactivation of UBXN2A, resulting in upregulation of UBXN2A in the cytoplasm, where UBXN2A binds and inhibits the oncoprotein mortalin-2

  3. Impaired stoichiometry between mtHsp40 and mtHsp70 promotes Opa1L cleavage, leading to cristae opening, decreased OXPHOS, and triggering of mitochondrial fragmentation after reduction in their chaperone function.

  4. mutations in HSPA9 result in congenital sideroblastic anemia inherited as an autosomal recessive trait

  5. Expression of mortalin decreased significantly in dopaminergic cells overexpressing A53T alpha-syn

  6. Results present the functional structure of human mortalin showing at least two domains and interacts with adenosine nucleotides with high affinity depending on the presence of Mg2 (show MUC7 ELISA Kits)+ ions.

  7. Mortalin is a key regulator of multiple signaling and metabolic pathways pivotal to medullary thyroid carcinoma cell survival and proliferation.

  8. Human mot-1, R126W, or P509S mutants lack mot-2 functions involved in carcinogenesis.

  9. Glutamine (show GFPT1 ELISA Kits) regulated ubiquitination processes of Grp75 and Apg-2 (show HSPA4 ELISA Kits).

  10. The functional interaction of mortalin with Parkin and PINK1, was investigated.

Mouse (Murine) Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. data imply a role for Hspa9 in B lymphopoiesis and Stat5 (show STAT5A ELISA Kits) activation downstream of IL-7 (show IL7 ELISA Kits) signaling

  2. Matrin 3 (show MATR3 ELISA Kits) interacts specifically with the heat shock proteins glucose-regulated protein 78 (show HSPA5 ELISA Kits), GRP75 and glutathione S-transferase (show GSTa2 ELISA Kits) pi isoform 2.

  3. down-regulation of mortalin may potentiate Abeta (show APP ELISA Kits)-mediated mitochondrial fragmentation and dysfunction in AD.

  4. the mortalin/DJ-1 (show PARK7 ELISA Kits) complex guards against mitochondrial oxidative stress and is indispensable for the maintenance of hematopoietic stem cells

  5. Inflammatory response of microglial cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein (show HSP90B1 ELISA Kits) 75/mortalin.

  6. Knockdown of Hspa9 results in a decrease in hematopoietic progenitors resulting in myelodysplastic syndromes.

  7. Data show that RNAi-mediated down-regulation of GRP75 and GRP75-blocking antibodies, both of which inhibited macromolecular endocytosis.

  8. The asymmetric segregation of mortalin in the bipotent cell line and its uniform distribution in a committed, lineage-restricted cell line raises the possibility that it may play a role in cell fate determination

  9. Mortalin imaging was used in normal and cancer cells with quantum dotimmuno-conjugates.

  10. We propose that the differential regulation of mortalin in AD and by the APOE (show APOE ELISA Kits) genotype is a cellular defense mechanism responding to increases in oxidative stress.

HSPA9 Antigen Profile

Antigen Summary

This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.

Gene names and symbols associated with HSPA9

  • heat shock 70kDa protein 9 (mortalin) (hspa9-a) antibody
  • heat shock 70kDa protein 9 (mortalin) (hspa9) antibody
  • heat shock 70kDa protein 9 (mortalin) (HSPA9) antibody
  • stress-70 protein, mitochondrial-like (HSPA9) antibody
  • heat shock protein 9 (Hspa9) antibody
  • 74kDa antibody
  • Csa antibody
  • GRP-75 antibody
  • Grp75 antibody
  • Hsc74 antibody
  • Hsp74 antibody
  • Hsp74a antibody
  • hspa9 antibody
  • Hspa9a antibody
  • HSPA9B antibody
  • Mortalin antibody
  • MOT antibody
  • Mot-2 antibody
  • Mot2 antibody
  • Mthsp70 antibody
  • MTHSP75 antibody
  • Pbp74 antibody

Protein level used designations for HSPA9

heat shock 70kDa protein 9 (mortalin) , heat shock 70kDa protein 9B , Stress-70 protein, mitochondrial-like protein , heat shock 70 kDa protein 9B , stress-70 protein, mitochondrial , GRP-75 , heat shock 70 kDa protein 9 , 75 kDa glucose-regulated protein , stress-70 protein, mitochondrial-like , heat shock 70kD protein 9B , mortalin, perinuclear , mortalin-2 , p66-mortalin , peptide-binding protein 74 , GRP 75 , heat shock 70kDa protein 9B (mortalin-2) , C3H-specific antigen , heat shock protein 9A , heat shock protein cognate 74 , heat shock protein, 74 kDa, A , heat shock protein, A , p66 MOT , PBP74 , heat shock 70kDa protein 9A , mortalin , mtHSP70 , 70 kDa heat shock protein , Heat shock 70 kDa protein 9

379314 Xenopus laevis
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714506 Macaca mulatta
100020208 Monodelphis domestica
100034032 Equus caballus
100173869 Pongo abelii
100406895 Callithrix jacchus
100521183 Sus scrofa
100590864 Nomascus leucogenys
416183 Gallus gallus
3313 Homo sapiens
517535 Bos taurus
474697 Canis lupus familiaris
15526 Mus musculus
291671 Rattus norvegicus
100689405 Cricetulus griseus
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