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Hemopoietic Cell Kinase (HCK) ELISA Kits

The protein encoded by HCK is a member of the Src family of tyrosine kinases. Additionally we are shipping HCK Antibodies (138) and HCK Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HCK 3055 P08631
HCK 15162 P08103
HCK 25734 P50545
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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 4.69 pg/ml 18.75-1200 pg/mL 96 Tests Log in to see 11 to 13 Days
96 Tests Log in to see 11 to 13 Days
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More ELISA Kits for HCK Interaction Partners

Human Hemopoietic Cell Kinase (HCK) interaction partners

  1. we provide evidence for involvement of HCK and FGR (show FGR ELISA Kits) in FCRL4 (show FCRL4 ELISA Kits)-mediated immunoregulation and for the functional importance of posttranslational modifications of the FCRL4 (show FCRL4 ELISA Kits) molecule.

  2. Interaction with the Src (show SRC ELISA Kits) homology (SH3-SH2) region of the Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.

  3. Interaction between Nef and Hck is important for Nef-dependent modulation of viral infectivity.

  4. Data indicate that combined treatment using SFK (LYN (show LYN ELISA Kits), HCK, or FGR (show FGR ELISA Kits)) and c-KIT (show KIT ELISA Kits) inhibitor dasatinib dasatinib and chemotherapy provides a novel approach to increasing p53 (show TP53 ELISA Kits) activity and enhancing targeting of acute myeloid leukemia (show BCL11A ELISA Kits) (AML (show RUNX1 ELISA Kits)) stem cells.

  5. The SRC (show SRC ELISA Kits) family tyrosine kinase (show TXK ELISA Kits) HCK and the ETS (show ETS1 ELISA Kits) family transcription factors SPIB (show SPIB ELISA Kits) and EHF (show EHF ELISA Kits) regulate transcytosis across a human follicle-associated epithelium model.

  6. This particular binding mode enables Hck SH3 to sense a specific non-canonical residue situated in the SH3 RT-loop of the kinase.

  7. the activation of Hck, Lyn and c-Src by Nef is highly conserved among all major clades of HIV-1

  8. There were significant differences in the genotype and allele distribution of -627 G/T polymorphism in Hck gene between cases and controls.

  9. Hck activation at the Golgi apparatus causes the HIV-1 Nef-induced c-Fms (show CSF1R ELISA Kits) proto-oncogene (show CSF1R ELISA Kits) N-glycosylation defect.

  10. Loss of HCK is associated with acute promyelocytic leukemia (show PML ELISA Kits).

Mouse (Murine) Hemopoietic Cell Kinase (HCK) interaction partners

  1. Data indicate that Src (show SRC ELISA Kits)-Family Kinases Hck and Fgr (show FGR ELISA Kits) regulate cytokine secretion by macrophages.

  2. Hck is not only progressively overexpressed in atherosclerosis, but it also controls critical molecular processes in monocyte influx, blood monocyte subset balance, macrophage accumulation, and the maintenance of atherosclerotic lesion stability.

  3. The Src (show SRC ELISA Kits) family kinases Hck, Fgr (show FGR ELISA Kits), and Lyn (show LYN ELISA Kits) are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.

  4. tyrosine phosphorylation of WASP (show WASL ELISA Kits) by Hck is required for proper macrophage functions

  5. Hck is one of the very few effectors of preosteoclast recruitment described to date and thereby plays a critical role in bone remodeling.

  6. Despite possessing enhanced killing, alveolar macrophage Hck/Fgr (show FGR ELISA Kits)/Lyn (show LYN ELISA Kits)-deficient ("triple-knockout") mice do not demonstrate enhanced inflammatory responses to Pneumocystis murina.

  7. Taken together, PKR (show EIF2AK2 ELISA Kits) and Hck were critical for DON-induced ribosomal recruitment of p38 (show CRK ELISA Kits), its subsequent phosphorylation, and, ultimately, p38 (show CRK ELISA Kits)-driven proinflammatory cytokine expression.

  8. Nef participates in HIV-1-induced multinucleated giant cells formation via a p61Hck- and lysosomal enzyme-dependent pathway

  9. spatial organization of podosomes as large rosettes, proteolytic degradation of extracellular matrix, and 3D migration appeared to be functionally linked and regulated by Hck in macrophages

  10. enhanced innate immune response in Hck(F/F) mice thereby skewing innate immunity from a reversible physiological host defense response to one causing irreversible tissue damage

Cow (Bovine) Hemopoietic Cell Kinase (HCK) interaction partners

  1. A truncated, mRNA-encoded src-related tyrosine kinase (show FRK ELISA Kits) HCK could function as an adaptor protein or as a competitive inhibitor in spermiogenesis or mature sperm functions.

  2. the presence of mRNAs encoding for hck and hck-tr in testicular germ cells; hck-tr being translated during spermatogenesis and expressed on mature ejaculated bull spermatozoa.

HCK Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Gene names and symbols associated with HCK

  • hemopoietic cell kinase (tklal-a) antibody
  • hemopoietic cell kinase (HCK) antibody
  • hemopoietic cell kinase (hck) antibody
  • hemopoietic cell kinase (Hck) antibody
  • AI849071 antibody
  • Bmk antibody
  • HCK antibody
  • Hctk antibody
  • JTK9 antibody
  • laloo antibody
  • MGC107870 antibody
  • p56Hck antibody
  • p59Hck antibody
  • p61Hck antibody

Protein level used designations for HCK

hemopoietic cell kinase , non-receptor protein tyrosine kinase laloo , tyrosine-protein kinase HCK-like , hematopoietic cell kinase , p59-HCK/p60-HCK , tyrosine-protein kinase HCK , B cell/myeloid kinase , B-cell/myeloid kinase , p56-HCK/p59-HCK , hemopoietic cell tyrosine kinase , p56-HCK

373700 Xenopus laevis
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100455620 Pongo abelii
100587780 Nomascus leucogenys
3055 Homo sapiens
15162 Mus musculus
25734 Rattus norvegicus
419280 Gallus gallus
280814 Bos taurus
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