Homeobox A10 Proteins (HOXA10)

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Additionally we are shipping HOXA10 Antibodies (69) and HOXA10 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HOXA10 3206 P31260
HOXA10 15395 P31310
Rat HOXA10 HOXA10 368057  
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Top HOXA10 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Yeast Heterodontus francisci His tag   1 mg Log in to see 60 to 71 Days
Yeast Morone saxatilis His tag   1 mg Log in to see 60 to 71 Days

HOXA10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Homeobox A10 (HOXA10) Interaction Partners

Human Homeobox A10 (HOXA10) interaction partners

  1. These results suggest that downregulation of HOXA10 in the decidual cells promotes the expression of a cascade in the trophoblast cells, leading to an increase in matrix metalloproteinases to facilitate invasion.

  2. Endometrial expression of HOXA10 and E-cadherin (show CDH1 Proteins) are reduced in women with recurrent implantation failure and recurrent miscarriage.

  3. Reduced expression of HOXA10 is associated with Hydrosalpinx.

  4. To summarize, significant differential methylation of HOXA10 and COMT (show COMT Proteins) promoter regions was found between the ectopic and eutopic endometrial tissues. This is the first study investigating the methylation of HOXA10 and COMT (show COMT Proteins) genes and their linkage to endometriosis in Chinese patients.

  5. using both knockdown and knockout approaches we show that Hottip expression is required for activation of the 5' Hoxa genes (Hoxa13 (show HOXA13 Proteins) and Hoxa10/11) and for retaining Mll1 at the 5' end of Hoxa. Moreover, we demonstrate that artificially inducing Hottip expression is sufficient to activate the 5' Hoxa genes and that Hottip RNA binds to the 5' end of Hoxa

  6. HOXA10 is overexpressed in oral squamous cell carcinoma (OSCC) and its expression is functionally associated with several important biological processes related to oral tumorigenesis, such as proliferation, migration and invasion.

  7. The results demonstrated that mutation in HOXA10 gene contributes to the pathogenesis of cryptorchidism, but may not be a common cause.

  8. The HOXA10 gene in women with endometriosis was hypomethylated compared to controls.

  9. HOXA10 was expressed at a high level in the K562/ADM (show ADM Proteins) cells, and knockdown of HOXA10 enhances the sensitivity of the K562/ADM (show ADM Proteins) cells to cytotoxic killing by the therapeutic drug, ADR (show AKR1B1 Proteins), as a result of the increased intracellular accumulation of ADR (show AKR1B1 Proteins).

  10. Regulated HOXA10 and HOXA11 (show HOXA11 Proteins) expression is necessary for endometrial receptivity; decreased HOXA10 or HOXA11 (show HOXA11 Proteins) expression leads to decreased implantation rates. Alternation of HOXA10 and HOXA11 (show HOXA11 Proteins) expression has been identified as a mechanism of the decreased implantation associated with endometriosis, polycystic ovarian syndrome, leiomyoma, polyps, adenomyosis, and hydrosalpinx.

Pig (Porcine) Homeobox A10 (HOXA10) interaction partners

  1. study identified an E(2)/P(4) response element of the porcine HOXA10 gene for the first time

  2. investigation of regulation of HOXA10 gene expression by estradiol and/or progesterone in porcine endometrium during estrous.

  3. Homeobox A10 expression in the porcine endometrium is closely related to the implantation process and stimulated by conceptus products.

Mouse (Murine) Homeobox A10 (HOXA10) interaction partners

  1. These results suggest that progesterone receptor (show PGR Proteins) overexpression in endometrial stromal cells, likely due to high progesterone levels, triggers cyclin D3 (show CCND3 Proteins) and Hoxa-10 overexpression, which may be involved in the pathological mechanisms of the mouse uterine decidual reaction.

  2. Hmgn5 (show HMGN5 Proteins) might act downstream of Hoxa10 to regulate the expression of Cox-2, Vegf (show VEGFA Proteins) and Mmp2 (show MMP2 Proteins).

  3. Our results suggest that NA10HD increases the number of gamma-globin-transduced HSCs that engraft, leading to an elevated number of fetal hemoglobin-containing red cells.

  4. we suggest that proper regional decidualization and polyploidy development requires FoxM1 (show FOXM1 Proteins) signaling downstream of Hoxa10 and cyclin D3 (show CCND3 Proteins).

  5. these studies demonstrate a previously undescribed role for HoxA10 in terminating emergency granulopoiesis, suggesting an important contribution by Hox (show MSH2 Proteins) proteins to the innate immune response.

  6. Hoxa10 cooperates with Nkx2-5 (show NKX2-5 Proteins) to regulate the timing of cardiac mesoderm differentiation.

  7. results show that reduced APC activity is sufficient to induce formation of epithelial inclusion cysts and support ovarian endometrioid adenocarcinoma development and suggest that induced HOXA10 expression and loss of PTEN are key mechanisms driving endometrioid histotype differentiation and progression

  8. a molecular mechanisms through which increased expression of HoxA10 increases Cdx4 expression by direct CDX4 activation and by Fgf2 (show FGF2 Proteins)-induced beta-catenin (show CTNNB1 Proteins) activity. This results in Cdx4-induced HoxA10-expression, creating a positive feedback mechanism

  9. Setbp1 (show SETBP1 Proteins) promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 (show HOXA9 Proteins) and Hoxa10.

  10. found that increased Fgf2 (show FGF2 Proteins) production by HoxA10-overexpressing myeloid progenitor cells induced a phosphoinositol 3-kinase-dependent increase in beta-catenin (show CTNNB1 Proteins) protein

HOXA10 Protein Profile

Protein Summary

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene.

Gene names and symbols associated with Homeobox A10 Proteins (HOXA10)

  • homeobox A10 (HOXA10)
  • homeobox protein Hox-A10-like (LOC100396925)
  • homeobox A10 (Hoxa10)
  • homeobox A11 (Hoxa11)
  • Hox-1.8 protein
  • HOX1 protein
  • HOX1.8 protein
  • HOX1H protein
  • Hoxa-10 protein
  • Hoxa10 protein
  • PL protein
  • RGD1564605 protein
  • RGD1566402 protein

Protein level used designations for Homeobox A10 Proteins (HOXA10)

homeobox A10 , homeobox A10, isoform 1 , homeobox protein Hox-A10-like , homeo box A10 , homeobox protein 1H , homeobox protein HOXA10 , homeobox protein Hox-1.8 , homeobox protein Hox-1H , homeobox protein Hox-A10 , homeobox protein A10

100137570 Papio anubis
100396925 Callithrix jacchus
3206 Homo sapiens
482373 Canis lupus familiaris
100737679 Sus scrofa
784386 Bos taurus
15395 Mus musculus
100717089 Cavia porcellus
776143 Gallus gallus
368057 Rattus norvegicus
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