Homeobox B13 Proteins (HOXB13)

HOXB13 encodes a transcription factor that belongs to the homeobox gene family. Additionally we are shipping HOXB13 Antibodies (72) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat HOXB13 HOXB13 303480  
HOXB13 15408 P70321
HOXB13 10481 Q92826
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Top HOXB13 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days

HOXB13 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,

More Proteins for Homeobox B13 (HOXB13) Interaction Partners

Mouse (Murine) Homeobox B13 (HOXB13) interaction partners

  1. Cdx (show CDX1 Proteins) and Wnt (show WNT2 Proteins) mutations and premature Hox13 (show HOXA5 Proteins) expression also cause similar neural dysmorphology

  2. Hoxb13 has a negative effect on skin wound repair

  3. Data demonstrate that FOXA1 directly regulates HOXB13 in human prostate epithelial cells, and show that this prostate-specific regulatory mechanism is conserved in mice.

  4. results suggest a specific role for Hoxb13 in a differentiation pathway that gives the ventral prostate epithelium a unique identity, as well as a more general role in ventral prostate morphogenesis that is redundant with other Hox13 (show HOXA5 Proteins) paralogs

  5. Hoxb13 knockout mice exhibit enhanced cutaneous wound healing.

  6. Epidermal HOXB13 signal was detected over the entire body surface, but surprisingly, essentially all of the signal was cytoplasmic in developing skin

  7. An increase of the Ala repeat above a certain length (22 Ala)in the Hoxd13 (show HOXD13 Proteins) sequence, resulting in synpolydactyly, is associated with a shift in the localization of Hox13 (show HOXA5 Proteins) from nuclear to cytoplasmic and aggregation.

  8. Hoxb13 cis (show CISH Proteins)-regulatory elements provide a powerful tool to achieve androgen-independent transgene expression in the prostate and distal colon-specific expression in the gastrointestinal tract

Human Homeobox B13 (HOXB13) interaction partners

  1. HOXB13 mutation is associated with prostate tumors.

  2. CCAT1 regulates HOXB13 as a molecular decoy for miR-7 (show LILRB1 Proteins), a microRNA that targets both CCAT1 and HOXB13, thus facilitating cell growth and migration in esophageal squamous cell carcinoma

  3. This study presents in silico prediction approaches of the deleterious ns single nucleotide polymorphisms (missense) in the homeobox (show Lbx1 Proteins) domain of human HOXB13 gene responsible for hereditary prostate cancer.

  4. This is the first study to investigate the HOXB13 G84E mutation in Danish men. The mutation was detected in 0.49% of controls and in 2.51% of cases, and was associated with 5.12-fold increased relative risk of being diagnosed with prostate cancer. In our RP cohort, HOXB13 mutation carriers were more likely to develop aggressive prostate cancer.

  5. HOXB13 is a useful marker for prostate origin when doubt exists regarding the site of the primary of a metastatic lesion

  6. Tumor-associated macrophage-secreted CXCL8 (show IL8 Proteins) downregulated the ERalpha (show ESR1 Proteins) expression of endometrial cancer cells via HOXB13, which may be associated with cancer invasion, metastasis and poor prognosis.

  7. Study provides insights suggesting that HOXB13 plays an important role in prostate tumorigenesis and malignant progression via the regulation of both p21 (show CDKN1A Proteins) and JNK (show MAPK8 Proteins) signaling.

  8. The Breast Cancer Index (BCI) is a continuous risk index model of two previously described biomarkers: molecular grade index (MGI) and HOXB13:IL17BR (H:I) ratio

  9. Studies indicate that the germline homeo box B13 protein (HOXB13) p.Gly84Glu mutation is significantly increased the risk of cancers.

  10. review the functions attributed to HOXB13, by highlighting the most recent findings supporting the hypothesis that HOXB13 might serve as a novel biomarker for the prognosis of prostate cancer

HOXB13 Protein Profile

Protein Summary

This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region.

Gene names and symbols associated with Homeobox B13 Proteins (HOXB13)

  • homeobox B13 (HOXB13)
  • homeobox B13 (LOC100345620)
  • homeo box B13 (Hoxb13)
  • homeobox B13 (Hoxb13)
  • HOXB13 protein
  • PSGD protein

Protein level used designations for Homeobox B13 Proteins (HOXB13)

homeobox B13 , homeo box B13 , homeobox protein Hox-B13

468433 Pan troglodytes
491060 Canis lupus familiaris
697572 Macaca mulatta
771676 Gallus gallus
100345620 Oryctolagus cuniculus
303480 Rattus norvegicus
15408 Mus musculus
10481 Homo sapiens
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