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anti-IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3) Antibodies

IKZF3 encodes a member of the Ikaros family of zinc-finger proteins. Additionally we are shipping IKZF3 Proteins (5) and IKZF3 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IKZF3 22780 O08900
IKZF3 303511  
IKZF3 22806 Q9UKT9
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Top anti-IKZF3 Antibodies at

Showing 10 out of 133 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-IKZF3 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB IKZF3 Antibody (Center) (ABIN651843) western blot analysis in mouse liver tissue lysates (15 µg/lane). This demonstrates the IKZF3 antibody detected IKZF3 protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COLO cells, using IKZF3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Mouse Un-conjugated IF Immunofluorescence of to ZNFN1A3 on HeLa cell . Detection limit for recombinant GST tagged ZNFN1A3 is approximately 10 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
Mouse Mouse PE FACS 100 μg Log in to see 10 to 12 Days
Mouse Mouse Alexa Fluor 647 FACS 100 μg Log in to see 10 to 12 Days
Human Mouse Un-conjugated IF, ELISA, WB Western Blot detection against Immunogen (81.73 KDa) . Immunofluorescence of monoclonal antibody to IKZF3 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: Aiolos/IKZF3 Antibody [NBP2-24495] - Analysis of IKZF3 in human spleen lysate in the 1) absence and 2) presence of immunizing peptide using this antibody at 0.25 ug/ml. Immunocytochemistry/Immunofluorescence: Aiolos/IKZF3 Antibody [NBP2-24495] - IKZF3 antibody was tested in Jurkat cells at a 1:40 dilution against Dylight 488 (Green). Alpha tubulin and nuclei were counterstained against Dylight 568 (Red) and DAPI (Blue), respectively. 0.1 mg Log in to see 5 to 7 Days
Mouse Mouse Un-conjugated ChIP, WB   100 μg Log in to see 1 to 2 Days

IKZF3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , ,
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Rat (Rattus) , ,

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Human , , , ,
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Top referenced anti-IKZF3 Antibodies

  1. Human Monoclonal IKZF3 Primary Antibody for IF - ABIN394045 : Matulić, Paradzik, Puskarić, Stipić, Antica: Analysis of Ikaros family splicing variants in human hematopoietic lineages. in Collegium antropologicum 2010 (PubMed)
    Show all 5 references for ABIN394045

  2. Mouse (Murine) Monoclonal IKZF3 Primary Antibody for FACS - ABIN2657113 : Cariappa, Tang, Parng, Nebelitskiy, Carroll, Georgopoulos, Pillai: The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21. in Immunity 2001 (PubMed)
    Show all 4 references for ABIN2657113

  3. Mouse (Murine) Monoclonal IKZF3 Primary Antibody for FACS - ABIN2662381 : Wang, Avitahl, Cariappa, Friedrich, Ikeda, Renold, Andrikopoulos, Liang, Pillai, Morgan, Georgopoulos: Aiolos regulates B cell activation and maturation to effector state. in Immunity 1998 (PubMed)
    Show all 4 references for ABIN2662381

  4. Human Polyclonal IKZF3 Primary Antibody for ICC, IF - ABIN4278882 : Zhu, Braggio, Shi, Kortuem, Bruins, Schmidt, Chang, Langlais, Luo, Jedlowski, LaPlant, Laumann, Fonseca, Bergsagel, Mikhael, Lacy, Champion, Stewart: Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma. in Blood 2014 (PubMed)

  5. Mouse (Murine) Monoclonal IKZF3 Primary Antibody for ChIP, WB - ABIN2668825 : Thompson, Cobb, Sabbattini, Meixlsperger, Parelho, Liberg, Taylor, Dillon, Georgopoulos, Jumaa, Smale, Fisher, Merkenschlager: Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits. in Immunity 2007 (PubMed)

  6. Human Monoclonal IKZF3 Primary Antibody for IF, ELISA - ABIN564938 : Matulic, Paradzik, Cicin-Sain, Kapitanovic, Dubravcic, Batinic, Antica: Ikaros family transcription factors in chronic and acute leukemia. in American journal of hematology 2009 (PubMed)

  7. Human Polyclonal IKZF3 Primary Antibody for WB - ABIN651843 : Mavaddat, Dunning, Ponder, Easton, Pharoah: Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009 (PubMed)

  8. Chicken Polyclonal IKZF3 Primary Antibody for WB - ABIN2780887 : Antica, Cicin-Sain, Sain, Kapitanovic, Matulic, Dzebro, Dominis: Aberrant Ikaros, Aiolos, and Helios expression in Hodgkin and non-Hodgkin lymphoma. in Blood 2008 (PubMed)

  9. Cow (Bovine) Polyclonal IKZF3 Primary Antibody for IHC, WB - ABIN2780886 : Koipally, Georgopoulos: A molecular dissection of the repression circuitry of Ikaros. in The Journal of biological chemistry 2002 (PubMed)

  10. Human Polyclonal IKZF3 Primary Antibody for ELISA, WB - ABIN1534187 : Hosokawa, Maeda, Takahashi, Suzuki, Seto: Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping. in Genomics 2000 (PubMed)

More Antibodies against IKZF3 Interaction Partners

Mouse (Murine) IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3) interaction partners

  1. These data place Aiolos in the emerging gene regulatory network controlling NK-cell maturation and function.

  2. study demonstrated that Aiolos silenced the Il2 (show IL2 Antibodies) locus, promoting TH17 differentiation in vitro and in vivo

  3. Aiolos and Ikaros (show IKZF1 Antibodies) bind to the c-myc (show MYC Antibodies) promoter in vivo and directly suppress c-myc (show MYC Antibodies) expression in pre-B cells.

  4. Normal Aiolos function is necessary to maintain immune homeostasis and suppress the development of systemic autoimmune disease; Aiolos is implicated as a possible candidate gene for systemic lupus erythematosus.

  5. A model is proposed for the control of Bcl-xL's anti-apoptotic role in IL-4 (show IL4 Antibodies)-deprived cells via association to the transcription factor Aiolos.

  6. Failure to generate high affinity plasma cells in the bone marrow and to sustain serum antibody titers is apparent after both primary and secondary immunization of Aiolos(-)(/)(-) mice with a range of hapten concentrations.

  7. A novel role for OBF-1 (show POU2AF1 Antibodies) and Aiolos in controlling the transcription and nuclear organization of genes involved in pre-BCR (show BCR Antibodies) function.

Human IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3) interaction partners

  1. Our data indicate a possible regulatory role for the multiple sclerosis-associated IKZF3 and IQGAP1 (show IQGAP1 Antibodies) variants.

  2. results indicate that overexpression of Aiolos may contribute to pathogenesis of SLE and RA

  3. Aiolos improved the survival of Nalm6 cells via PTEN (show PTEN Antibodies) and Aktdependent processes.

  4. NFKB1 (show NFKB1 Antibodies), CD27 (show CD27 Antibodies), LAG3 (show LAG3 Antibodies) and IKZF3 are new susceptibility genes for psoriasis.

  5. lentivirus-mediated AIOLOS overexpression in Jurkat cells induced cell apoptosis, arrested the cell cycle at the G0/G1 phase, and synergistically increased the sensitivity of Jurkat cells to etoposide by inhibiting NF-kappaB (show NFKB1 Antibodies) activity.

  6. The allele T of rs10852936 surrounding the IKZF3-ZPBP2 (show ZPBP2 Antibodies) locus confers risk for early-onset psoriasis.

  7. A strong association between rs907091 in the IKZF3 gene and SLE was identified.

  8. The immunosuppressive enzyme IL4I1 (show IL4I1 Antibodies) expressed differentially in human induced Aiolos+, but not natural Helios (show ZNFN1A2 Antibodies)+, FOXP3 (show FOXP3 Antibodies)+ Treg cells.

  9. A strong allelic association between SNPs in the 17q21 region (IKZF3) and asthma has been confirmed for the Latinos population.

  10. Overexpression of AIOLOS inhibits cell proliferation, suppresses apoptosis and arrests the cell cycle at the G0/G1 phase in vitro.

IKZF3 Antigen Profile

Protein Summary

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

Gene names and symbols associated with IKZF3

  • IKAROS family zinc finger 3 (Ikzf3) antibody
  • IKAROS family zinc finger 3 (Aiolos) (IKZF3) antibody
  • IKAROS family zinc finger 3 (Aiolos) (ikzf3) antibody
  • 5830411O07Rik antibody
  • aio antibody
  • aiolos antibody
  • Zfpn1a3 antibody
  • znfn1a3 antibody

Protein level used designations for IKZF3

ikaros family zinc finger protein 3 , zinc finger protein Aiolos , zinc finger protein, subfamily 1A, 3 (Aiolos) , lymphoid transcription factor

22780 Mus musculus
303511 Rattus norvegicus
22806 Homo sapiens
540676 Bos taurus
444381 Xenopus laevis
395614 Gallus gallus
491020 Canis lupus familiaris
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