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Not yet known.. Additionally we are shipping IFI35 Antibodies (80) and IFI35 Kits (10) and many more products for this protein.
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Study found that TLR3 (show TLR3 Proteins) signaling induces the expression of IFI35, and IFI35 negatively regulates IFN-beta (show IFNB1 Proteins)-P-STAT1 (show STAT1 Proteins)-RIG-I (show DDX58 Proteins)-CXCL10 (show CXCL10 Proteins)/CCL5 (show CCL5 Proteins) axis in U373MG cells. This suggests that IFI35 expressed in astrocytes may play an important role in regulating the innate immune system in astrocytoma cells.
Activation of TLR3 (show TLR3 Proteins) by poly IC induces the IFI35 expression in Mesangial Cells. Regional expression of IFI35 and its dysregulation may be involved in the pathogenesis of glomerular inflammation in CKD.
Trim21 (show TRIM21 Proteins) regulates Nmi (show MYO1C Proteins)-IFI35 complex-mediated inhibition of innate antiviral response
Knockdown of IFP35 expression abolished pEGFP-N1-2C and pEGFP-N1-Nmi (show MYO1C Proteins)-induced activation of type I interferon (show IFNA Proteins) promoters.
IFI35 negatively regulates RIG-I (show DDX58 Proteins) antiviral signaling and supports vesicular stomatitis virus replication.
IRF-1 (show IRF1 Proteins) also activates IFP35 expression in an IFN-gamma (show IFNG Proteins)-inducible manner.
Dissociation of the IFN-induced protein IFP35 from NMI (show MYO1C Proteins) is a newly defined specific cytoplasmic event occurring during apoptosis.
The results provide a novel role of CKIP-1 (show PLEKHO1 Proteins) in cytokine signaling response and the biochemical mechanism, by which two previously identified modulators IFP35 and Nmi (show MYO1C Proteins) are involved via interactions.
IFP35 can interact with the bovine Tas (show MAP3K4 Proteins) (BTas) regulatory protein of bovine foamy virus; overexpression of IFP35 disturbs the ability of BTas to activate viral-gene transcription and inhibits viral replication.
Not yet known.
interferon-induced 35 kDa protein
, interferon-induced protein 35
, IFP 35
, interferon-induced 35 kDa protein homolog