Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by IL18 is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Additionally we are shipping IL 18 Kits (117) and IL 18 Proteins (66) and many more products for this protein.
Showing 10 out of 217 products:
Human Polyclonal IL 18 Primary Antibody for IHC, WB - ABIN223550
Squires, Muehlbauer, Brojatsch: Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing. in The Journal of biological chemistry 2007
Show all 5 references for ABIN223550
Mouse (Murine) Monoclonal IL 18 Primary Antibody for WB - ABIN1449292
Clandinin: Fat absorption in newborns. in Pediatric research 2001
Show all 3 references for ABIN1449292
Rat (Rattus) Monoclonal IL 18 Primary Antibody for IP - ABIN1449293
Jordan, Guo, Yun, Sarma, Warner, Crouch, Senaldi, Ulich, Ward: Role of IL-18 in acute lung inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2001
Show all 3 references for ABIN1449293
Cynomolgus Polyclonal IL 18 Primary Antibody for ELISA, WB - ABIN2001765
Dinarello: IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family. in The Journal of allergy and clinical immunology 1999
Show all 2 references for ABIN2001765
Mouse (Murine) Polyclonal IL 18 Primary Antibody for FACS, IP - ABIN1043826
Okamura, Tsutsi, Komatsu, Yutsudo, Hakura, Tanimoto, Torigoe, Okura, Nukada, Hattori: Cloning of a new cytokine that induces IFN-gamma production by T cells. in Nature 1995
NLRP1 (show NLRP1 Antibodies) is an innate immune sensor that functions in the context of metabolic stress to produce IL-18, preventing obesity and metabolic syndrome.
IL-18 is sufficient to protect Birc3 (show BIRC3 Antibodies)-deficient mice from sodium dodecyl sulfate-induced colitis.
IL-18 plays a facilitative role via NF-kappaB (show NFKB1 Antibodies) activation in pulmonary hypertension formation.
IL-18 is a key epithelial-derived cytokine that differentially regulates distinct subsets of intestinal CD4 (show CD4 Antibodies)(+) T cells during both homeostatic and inflammatory conditions
Genetic ablation of IL-18 does not protect mice against maladaptive right ventricular remodeling following exposure to hypobaric hypoxia.
We conclude that in the systemic lupus erythematosus syndrom IL-18 is involved specifically in the renal pathogenesis
These results uncover the direct role of IL-18 in promoting goblet cell dysfunction during colitis, leading to breakdown of the mucosal barrier.
IL-18 is a potent stimulator of Chi3l1 (show CHI3L1 Antibodies) and that Chi3l1 (show CHI3L1 Antibodies) is an important mediator of IL-18-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.
macrophages are not involved in IL-18-mediated susceptibility to L. amazonensis.
The published data prompt to the hypothesis that IL-18 induces a broad spectrum of COPD (show ARCN1 Antibodies)-like inflammatory and remodeling responses in the murine lung
Study reports that the monocyte-derived cytokines IL-12 (show IL12A Antibodies) and IL-18 act synergistically on porcine gammadelta T cells to induce IFN-gamma (show IFNG Antibodies) production. Additional stimuli such as the mitogen ConA and IL-2 (show IL2 Antibodies) are necessary to activate the cells for enhanced proliferation.
IL-18 concentration in saliva (show RAG1AP1 Antibodies) was significantly increased during a 60-min acute immobilization stress in thirteen 5-month-old pigs. These results are the first evidence of a stress-related change of IL-18 in pig saliva (show RAG1AP1 Antibodies).
endometrial expression of CASP1 (show CASP1 Antibodies) and IL18 associated with pregnancy establishment; alteration of CASP1 (show CASP1 Antibodies) and IL18 following premature exposure of uterus to estrogen during early pregnancy may contribute to conceptus loss between Days 15 to 18 of pregnancy
Porcine IL-18 regulates anti-pig cellular rejection in C57BL/6 mice.
no confirmatory evidence for the hypothesis of IL-10 (show IL10 Antibodies) and IL-18 alleles modulating the risk of cognitive impairment in Chinese Parkinson's disease patients was obtained.
Kaplan-Meier analysis evidenced a weak effect of IL-18-137G/C genotypes on graft survival after kidney transplantation.
We conclude that IL-17A (show IL17A Antibodies) is a previously unrecognized effector of IL-18-mediated injury in neonatal sepsis and that disruption of the deleterious and tissue-destructive IL-18/IL-1 (show IL1A Antibodies)/IL-17A (show IL17A Antibodies) axis represents a novel therapeutic approach to improve outcomes for human neonates with sepsis.
The IL-18 -137 G/C polymorphism was significantly associated with an increased risk of recurrent pregnancy loss under a recessive genetic model. For the -607C/A mutation, no association was found under any genetic models.
Cancer cells can produce IL-18, which is involved in the process of angiogenesis, stimulates invasion and metastasis. Decrease in SIPA for the production of IL-6 (show IL6 Antibodies) and GCSF (show CSF3 Antibodies) by peripheral blood cells could serve as an indicator of malignant progression in invasive ductal breast carcinoma.
IL-18 is associated with insulin (show INS Antibodies) resistance and other cardiovascular risk factors; the CC genotype of the rs1834481 SNP of the IL-18 gene was significantly associated with lower levels of IL-18; the GG genotype of the rs7559479 SNP was associated with significant higher levels of IL-18
Meta-analysis showed that the -607A/C, -920C/T, and -105A/C polymorphisms in IL-18 were significantly associated with increased rheumatoid arthritis risk. However, the -137C/G polymorphism was not associated with rheumatoid arthritis risk under any genetic model.
review summarizes the biology of the IL-18/IL-18BP (show IL18BP Antibodies)/IL-18R system and its role in the host defense against infections
IL-18 seems to be important indicator and predictor of cardiovascular death in two-year follow-up among non-diabetic patients suffering from CKD, with history of AMI (show CFD Antibodies) in the previous year.
IL-18 is an important predictor of mortality in humans with both severe sepsis and septic shock, independent of IL-1beta (show IL1B Antibodies)
These results suggest that BAPC-1 is a stem/progenitor cell line and modulates the immuno-endocrine function of the anterior pituitary cells through its production of interleukin-18 and the IL-18 receptor.
Pressure overload, while enhancing IL-18 and IL-18R expression in hypertrophied and failing hearts, markedly attenuated the level of expression of the endogenous IL-18 antagonist IL-18BP (show IL18BP Antibodies).
The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, IL-1 gamma
, interferon gamma-inducing factor
, interferon-gamma-inducing factor
, interleukin-1 gamma
, interferon gamma inducing factor
, Interferon gamma-inducing factor
, interleukin 18
, uncharacterized protein LOC100734451