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The protein encoded by IL18 is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Additionally we are shipping IL 18 Kits (127) and IL 18 Proteins (60) and many more products for this protein.
Showing 10 out of 209 products:
Human Polyclonal IL 18 Primary Antibody for IHC, WB - ABIN223550
Squires, Muehlbauer, Brojatsch: Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing. in The Journal of biological chemistry 2007
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Mouse (Murine) Monoclonal IL 18 Primary Antibody for WB - ABIN1449292
Clandinin: Fat absorption in newborns. in Pediatric research 2001
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Rat (Rattus) Monoclonal IL 18 Primary Antibody for IP - ABIN1449293
Jordan, Guo, Yun, Sarma, Warner, Crouch, Senaldi, Ulich, Ward: Role of IL-18 in acute lung inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2001
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Cynomolgus Polyclonal IL 18 Primary Antibody for ELISA, WB - ABIN2001765
Dinarello: IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family. in The Journal of allergy and clinical immunology 1999
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Human Polyclonal IL 18 Primary Antibody for WB - ABIN1944748
Ushio, Namba, Okura, Hattori, Nukada, Akita, Tanabe, Konishi, Micallef, Fujii, Torigoe, Tanimoto, Fukuda, Ikeda, Okamura, Kurimoto: Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. in Journal of immunology (Baltimore, Md. : 1950) 1996
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Mouse (Murine) Polyclonal IL 18 Primary Antibody for FACS, IP - ABIN1043826
Okamura, Tsutsi, Komatsu, Yutsudo, Hakura, Tanimoto, Torigoe, Okura, Nukada, Hattori: Cloning of a new cytokine that induces IFN-gamma production by T cells. in Nature 1995
IL-18 plays a facilitative role via NF-kappaB (show NFKB1 Antibodies) activation in pulmonary hypertension formation.
IL-18 is a key epithelial-derived cytokine that differentially regulates distinct subsets of intestinal CD4 (show CD4 Antibodies)(+) T cells during both homeostatic and inflammatory conditions
Genetic ablation of IL-18 does not protect mice against maladaptive right ventricular remodeling following exposure to hypobaric hypoxia.
We conclude that in the systemic lupus erythematosus syndrom IL-18 is involved specifically in the renal pathogenesis
These results uncover the direct role of IL-18 in promoting goblet cell dysfunction during colitis, leading to breakdown of the mucosal barrier.
IL-18 is a potent stimulator of Chi3l1 (show CHI3L1 Antibodies) and that Chi3l1 (show CHI3L1 Antibodies) is an important mediator of IL-18-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.
macrophages are not involved in IL-18-mediated susceptibility to L. amazonensis.
The published data prompt to the hypothesis that IL-18 induces a broad spectrum of COPD (show ARCN1 Antibodies)-like inflammatory and remodeling responses in the murine lung
Following hypoxic ischemic insult, long term creatine monohydrate supplementation up regulates the IL-6 (show IL6 Antibodies) and IL-18 concentrations triggering the neuroinflammatory and neuroprotective responses.
High and fluctuating levels of glucose may be associated with inflammation and diabetic atherosclerosis by regulating the expression levels of IL-18.
Study reports that the monocyte-derived cytokines IL-12 (show IL12A Antibodies) and IL-18 act synergistically on porcine gammadelta T cells to induce IFN-gamma (show IFNG Antibodies) production. Additional stimuli such as the mitogen ConA and IL-2 (show IL2 Antibodies) are necessary to activate the cells for enhanced proliferation.
IL-18 concentration in saliva (show RAG1AP1 Antibodies) was significantly increased during a 60-min acute immobilization stress in thirteen 5-month-old pigs. These results are the first evidence of a stress-related change of IL-18 in pig saliva (show RAG1AP1 Antibodies).
endometrial expression of CASP1 (show CASP1 Antibodies) and IL18 associated with pregnancy establishment; alteration of CASP1 (show CASP1 Antibodies) and IL18 following premature exposure of uterus to estrogen during early pregnancy may contribute to conceptus loss between Days 15 to 18 of pregnancy
Porcine IL-18 regulates anti-pig cellular rejection in C57BL/6 mice.
Letter: Knockdown of either filaggrin (show FLG Antibodies) or loricrin (show LOR Antibodies) increases the productions of interleukin (IL)-1alpha, IL-8 (show IL8 Antibodies), IL-18 and granulocyte macrophage colony-stimulating factor (show CSF2 Antibodies) in stratified human keratinocytes.
the -607 C/A polymorphism in the IL-18 gene may be associated with susceptibility to esophageal cancer.
IL-18 and IL-18R polymorphisms may contribute to the development and lymph node metastasis of PTC (show F9 Antibodies).
IL-18 -137G/C polymorphism contributed to TB susceptibility in Chinese Han population.
levels of IL-18, but not those of IL-18BP (show IL18BP Antibodies) or sIL (show PMEL Antibodies)-18R1 are higher in primary Sjogren's syndrome patients than those in controls.
Correlation patterns of IL-18/anti-IL-18 auto-Abs system differed in healthy donors and multiple sclerosis patients
genetic variants in the IL-18 gene may be associated with susceptibility to Helicobacter pylori infection in the Korean population
These data suggest that genetic variation within the promoter region of IL18 is directly involved in the susceptibility to infection by Trypanosoma cruzi, which provides novel insight into disease pathophysiology.
Our meta-analysis demonstrates that the IL-18 -607 C/A polymorphism may be associated with susceptibility to T1D in Asians, but not in Europeans.
this study identified a significant association between systemic lupus erythematosus and two single nucleotide polymorphisms within the IL-18 gene promoter region (rs360719 and rs1946518) in a European population, but not in populations of Asian origin.
These results suggest that BAPC-1 is a stem/progenitor cell line and modulates the immuno-endocrine function of the anterior pituitary cells through its production of interleukin-18 and the IL-18 receptor.
Pressure overload, while enhancing IL-18 and IL-18R expression in hypertrophied and failing hearts, markedly attenuated the level of expression of the endogenous IL-18 antagonist IL-18BP (show IL18BP Antibodies).
The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, IL-1 gamma
, interferon gamma-inducing factor
, interferon-gamma-inducing factor
, interleukin-1 gamma
, interferon gamma inducing factor
, Interferon gamma-inducing factor
, interleukin 18
, uncharacterized protein LOC100734451