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The protein encoded by IL18 is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Additionally we are shipping IL 18 Kits (127) and IL 18 Proteins (75) and many more products for this protein.
Showing 10 out of 221 products:
Human Polyclonal IL 18 Primary Antibody for IHC, WB - ABIN223550
Squires, Muehlbauer, Brojatsch: Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing. in The Journal of biological chemistry 2007
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Mouse (Murine) Monoclonal IL 18 Primary Antibody for WB - ABIN1449292
Clandinin: Fat absorption in newborns. in Pediatric research 2001
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Human Monoclonal IL 18 Primary Antibody for FACS, WB - ABIN4900609
Gatault, Delbeke, Driss, Sarazin, Dendooven, Kahn, Lefèvre, Capron: IL-18 Is Involved in Eosinophil-Mediated Tumoricidal Activity against a Colon Carcinoma Cell Line by Upregulating LFA-1 and ICAM-1. in Journal of immunology (Baltimore, Md. : 1950) 2015
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Rat (Rattus) Monoclonal IL 18 Primary Antibody for IP - ABIN1449293
Jordan, Guo, Yun, Sarma, Warner, Crouch, Senaldi, Ulich, Ward: Role of IL-18 in acute lung inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2001
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Cynomolgus Polyclonal IL 18 Primary Antibody for ELISA, WB - ABIN2001765
Dinarello: IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family. in The Journal of allergy and clinical immunology 1999
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Mouse (Murine) Polyclonal IL 18 Primary Antibody for FACS, IP - ABIN1043826
Okamura, Tsutsi, Komatsu, Yutsudo, Hakura, Tanimoto, Torigoe, Okura, Nukada, Hattori: Cloning of a new cytokine that induces IFN-gamma production by T cells. in Nature 1995
Data, including data from studies in knockout mice, suggest that TNF (tumor necrosis factor (show TNF Antibodies)), TNFR1 (show TNFRSF1A Antibodies) (TNF (show TNF Antibodies) receptor 1), and IL18 (interleukin 18) are involved in liver lipid metabolism. IL18 or TNFR1 (show TNFRSF1A Antibodies) knockout mice on chow show higher liver triglyceride deposition than wild-type mice fed chow; in IL18 or TNFR1 (show TNFRSF1A Antibodies) knockout mice, high-refined-carbohydrate diet does not lead to fatty liver disease as it does in wild-type mice.
GABA-B receptor antagonists reduced Il18 levels in male mice and increased Il18 levels in female mice following neonatal hypoxia ischemia.
NLRP1 (show NLRP1 Antibodies) is an innate immune sensor that functions in the context of metabolic stress to produce IL-18, preventing obesity and metabolic syndrome.
IL-18 is sufficient to protect Birc3 (show BIRC3 Antibodies)-deficient mice from sodium dodecyl sulfate-induced colitis.
IL-18 plays a facilitative role via NF-kappaB (show NFKB1 Antibodies) activation in pulmonary hypertension formation.
IL-18 is a key epithelial-derived cytokine that differentially regulates distinct subsets of intestinal CD4 (show CD4 Antibodies)(+) T cells during both homeostatic and inflammatory conditions
Genetic ablation of IL-18 does not protect mice against maladaptive right ventricular remodeling following exposure to hypobaric hypoxia.
We conclude that in the systemic lupus erythematosus syndrom IL-18 is involved specifically in the renal pathogenesis
These results uncover the direct role of IL-18 in promoting goblet cell dysfunction during colitis, leading to breakdown of the mucosal barrier.
IL-18 is a potent stimulator of Chi3l1 (show CHI3L1 Antibodies) and that Chi3l1 (show CHI3L1 Antibodies) is an important mediator of IL-18-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.
Study reports that the monocyte-derived cytokines IL-12 (show IL12A Antibodies) and IL-18 act synergistically on porcine gammadelta T cells to induce IFN-gamma (show IFNG Antibodies) production. Additional stimuli such as the mitogen ConA and IL-2 (show IL2 Antibodies) are necessary to activate the cells for enhanced proliferation.
IL-18 concentration in saliva (show RAG1AP1 Antibodies) was significantly increased during a 60-min acute immobilization stress in thirteen 5-month-old pigs. These results are the first evidence of a stress-related change of IL-18 in pig saliva (show RAG1AP1 Antibodies).
endometrial expression of CASP1 (show CASP1 Antibodies) and IL18 associated with pregnancy establishment; alteration of CASP1 (show CASP1 Antibodies) and IL18 following premature exposure of uterus to estrogen during early pregnancy may contribute to conceptus loss between Days 15 to 18 of pregnancy
Porcine IL-18 regulates anti-pig cellular rejection in C57BL/6 mice.
IL-18 polymorphisms may influence tacrolimus elimination in lung transplantation patients.
Study showed that adipokine leptin (show LEP Antibodies) triggered macrophage- related cytokine IL-18 production, possibly contributing to tumor progression in breast cancer cells.
Results provide evidence for IL18-607C/A variation related to the pathogenesis of non-small cell lung cancer in the Chinese population studied.
findings resolve a long-standing contradiction regarding a tumor-suppressive role for IL18 in established hepatocellular carcinoma and provide a mechanistic explanation for the complex relationship between its expression pattern and hepatocellular carcinoma prognosis
IL-18 -372C/G did not contribute to the risk of glioma development in the co-dominant, dominant, and recessive models. Therefore, the IL-18 -607C/A polymorphism was significantly correlated with the risk of Coronary artery disease development.
The IL-18 -607C/A and -137G/C polymorphisms do not influence susceptibility to acute pancreatitis in the Chinese patient cohort.
both ETA and ETB (show EDNRB Antibodies) receptor expression in the renal cortex were significantly attenuated by ovariectomy, and this reduction was not evident in OVX+E2 rats. SIGNIFICANCE: These data suggest that ovarian hormones regulate ET receptor expression and may contribute to sex differences in cardiovascular and renal health.
The expression levels of the TNF-alpha (show TNF Antibodies), IL-18 and cTnI (show TNNI3 Antibodies) and the expression levels of the miR-1 (show FSD1 Antibodies) and miR (show MLXIP Antibodies)-146b could be used to predict viral myocarditis among children.
The relationship between variants of IL-10 (show IL10 Antibodies) and IL-18 in the response to antiviral treatment in hepatitis C patients in Egypt is reported.
Significant associations were detected between the IL-18 rs187238(G/C) polymorphism and chronic leukemia. The CC genotype may be associated with the risk of CLL. There were no significant associations between the IL-18 rs61667799(G/T), rs5744227(C/G), or rs5744228(A/G) polymorphisms and CLL or CML.
These results suggest that BAPC-1 is a stem/progenitor cell line and modulates the immuno-endocrine function of the anterior pituitary cells through its production of interleukin-18 and the IL-18 receptor.
Pressure overload, while enhancing IL-18 and IL-18R expression in hypertrophied and failing hearts, markedly attenuated the level of expression of the endogenous IL-18 antagonist IL-18BP (show IL18BP Antibodies).
The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, IL-1 gamma
, interferon gamma-inducing factor
, interferon-gamma-inducing factor
, interleukin-1 gamma
, interferon gamma inducing factor
, Interferon gamma-inducing factor
, interleukin 18
, uncharacterized protein LOC100734451