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The protein encoded by IL37 is a member of the interleukin 1 cytokine family. Additionally we are shipping Interleukin 37 Kits (98) and Interleukin 37 Proteins (42) and many more products for this protein.
Showing 10 out of 113 products:
Human Monoclonal IL37 Primary Antibody for FACS - ABIN2661225
Lee, Trepicchio, Oestreicher, Pittman, Wang, Chamian, Dhodapkar, Krueger: Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. in The Journal of experimental medicine 2004
Show all 9 references for ABIN2661225
Human Monoclonal IL37 Primary Antibody for ICFC, IP - ABIN2665146
Oppmann, Lesley, Blom, Timans, Xu, Hunte, Vega, Yu, Wang, Singh, Zonin, Vaisberg, Churakova, Liu, Gorman, Wagner, Zurawski, Liu, Abrams, Moore, Rennick, de Waal-Malefyt, Hannum, Bazan, Kastelein: Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. in Immunity 2001
Show all 6 references for ABIN2665146
Mouse (Murine) Monoclonal IL37 Primary Antibody for FACS - ABIN2665148
Aggarwal, Ghilardi, Xie, de Sauvage, Gurney: Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. in The Journal of biological chemistry 2003
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Human Polyclonal IL37 Primary Antibody for WB - ABIN2474991
Beun, van Eendenburg, Corver, van de Velde, Fleuren et al.: T-cell retargeting using bispecific monoclonal antibodies in a rat colon carcinoma model. I. Significant bispecific lysis of syngeneic colon carcinoma CC531 is critically dependent on prolonged ... in Journal of immunotherapy : official journal of the Society for Biological Therapy 1992
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Mouse (Murine) Monoclonal IL37 Primary Antibody for FACS, IP - ABIN2665831
Verreck, de Boer, Langenberg, Hoeve, Kramer, Vaisberg, Kastelein, Kolk, de Waal-Malefyt, Ottenhoff: Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria. in Proceedings of the National Academy of Sciences of the United States of America 2004
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Human Polyclonal IL37 Primary Antibody for ICC, ELISA - ABIN1002629
Hunter: New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. in Nature reviews. Immunology 2005
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Human Polyclonal IL37 Primary Antibody for IF (p), IHC (p) - ABIN673179
Yang, Gao, Shi, Zhou, Qu, Xu, Shan, Teng: Effect of iodine excess on Th1, Th2, Th17, and Treg cell subpopulations in the thyroid of NOD.H-2h4 mice. in Biological trace element research 2014
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These results demonstrated that IL-37 might manifest as a critical protein involving in immunosuppression of human CD4 (show CD4 Antibodies)(+)CD25 (show IL2RA Antibodies)(+)Tregs.
The expression of IL-37 was decreased in renal cell carcinoma (show MOK Antibodies) patients and was negatively correlated with tumor progression.
tubular epithelial cells express the IL-18 contra-regulatory protein IL-37 as an endogenous control mechanism to reduce inflammation
research demonstrated, for the first time, that anti-inflammatory active components (triptolide and triptonide) upregulated the expression of IL-37 most likely via activation of the ERK1/2 (show MAPK1/3 Antibodies) and p38 MAPK (show MAPK14 Antibodies) pathways.
The results suggest serum IL-37 levels were increased in rheumatoid arthritis (RA) patients and were positively associated with disease activity, IL-17 (show IL17A Antibodies)/IL-23 (show IL23A Antibodies) and bone loss in RA, suggesting that IL-37 may play a critical role in the pathogenesis of RA.
IL-37 requires IL-18Ralpha and SIGIRR (show SIGIRR Antibodies)/IL-1R8 to diminish allergic airway inflammation in mice
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
, IL-1 zeta
, IL-1F7b (IL-1H4, IL-1H, IL-1RP1)
, IL-1X protein
, IL1F7 (canonical product IL-1F7b)
, interleukin 1 family member 7
, interleukin 1, zeta
, interleukin-1 homolog 4
, interleukin-1 superfamily z
, interleukin-1-related protein