anti-Interleukin 6 (IL6) Antibodies

Cytokine with a wide variety of biological functions.

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More Antibodies against Interleukin 6 Interaction Partners

Mouse (Murine) Interleukin 6 (IL6) interaction partners

  1. IL-6 directly increases IL-10 (show IL10 Antibodies) production and participates in the counter-inflammatory response after acute kidney injury.

  2. This work demonstrates that autocrine IL-6 signaling in the gut (show GUSB Antibodies) epithelium regulates crypt homeostasis through the Paneth cells and the Wnt (show WNT2 Antibodies) signaling pathway.

  3. Early and direct IL-6 signals to memory CD4 (show CD4 Antibodies) T cells are required to program maximal secondary effector responses at the site of infection during heterosubtypic challenge, indicating a novel role for a costimulatory cytokine in recall responses.

  4. 6 h post injury, IL-6 mRNA expression was significantly lower in diabetic wounds. Abnormal macrophage activation, but not the lower abundance of CD68 (show CD68 Antibodies)-expressing macrophages, was found to be characteristic of diabetic wounds. IL-6 played a key role in facilitating non-diabetic fibroblast migration during wound healing via the p38 MAPK (show MAPK14 Antibodies)-Akt (show AKT1 Antibodies) pathway. This signaling pathway was found to be dysfunctional in diabetic fibroblasts

  5. Social isolation also increased IL-6 levels in the medial prefrontal cortex, and administration of an IL-6 inhibitor (ND50 = 0.01-0.03 mug for 0.25 ng/ml IL-6) ameliorated remyelination impairments

  6. Adipose-derived stem cells play a pro-malignant role in tumor development of Lewis lung carcinoma cells by particularly promoting cancer stem cell property through interleukin-6 paracrine circuit.

  7. Absence of IL-6 did not affect overall pathogenesis of Bacillus cereus endophthalmitis.

  8. SorLA (show SORL1 Antibodies) ectodomain, released from the cell membrane upon enzymatic cleavage of full-length SorLA (show SORL1 Antibodies), may act as an IL-6 carrier protein that stabilizes IL-6 and its capacity for trans signaling.

  9. These findings suggest that downregulation of miR (show MLXIP Antibodies)-142-3p in macrophages of aged mice might contribute to IL-6-associated aging disorders and that epigenetic modification might be involved in age-related inflammatory diseases.

  10. IL-6 can directly induce the transition of HSCs toward myofibroblast-like cells. The effect is mediated by the activation of both MAPK (show MAPK1 Antibodies) and JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling pathways. Elimination of either MAPK (show MAPK1 Antibodies) or JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling pathways inhibits HSC (show FUT1 Antibodies) stimulation

Human Interleukin 6 (IL6) interaction partners

  1. Results show that SDF-1 and IL-6 expression level is regulated by CHEK2 in breast stromal fibroblasts.

  2. Minor allele of rs1800795 and rs2069837 of Il-6 gene and its interaction were associated with increased cervical cancer risk.

  3. miR (show MLXIP Antibodies)-146a, miR (show MLXIP Antibodies)-146b, and miR (show MLXIP Antibodies)-155 are exerting anti-inflammatory properties by down-regulating IL-6 and IL-8 (show IL8 Antibodies), and influencing the expression of HSP10 (show HSPE1 Antibodies) in the activated endothelium

  4. GG SNP at IL-6: rs1800795 may indicate an increased risk of metastasis of primary breast cancer.

  5. TNFalpha (show TNF Antibodies) significantly increased LIF (show LIF Antibodies) expression in uncontrolled asthma. A similar trend was observed regarding IL-6.

  6. These data suggest that, without infection, inactivated-H5N1 induces mRNA expression of IL-6 and CXCL8 (show IL8 Antibodies) by a mechanism, or mechanisms, requiring interaction between viral hemagglutinin (show HA Antibodies) and alpha-2,3 sialic acid receptors at the cell membrane of host cells, and involves activation of P2Y6 (show P2RY6 Antibodies) purinergic receptors.

  7. IL-6 SNPs were associated with pulmonary tuberculosis with co-morbid diabetes in patients and their household contacts.

  8. DEK (show DEK Antibodies) correlates with IL6 expression in HPV16+/p16 (show CDKN2A Antibodies)+ oropharyngeal squamous cell carcinomas (OPSCC).

  9. Peritoneal membrane dysfunction in long-term peritoneal dialysis patients may result from IL-6 promotion of epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2 (show JAK2 Antibodies)/STAT3 (show STAT3 Antibodies) signaling pathway.

  10. The associations of diabetes, combined with the polymorphisms in the genes of fat mass and obesity-associated (show FTO Antibodies) gene (FTO (show FTO Antibodies)), interleukin 6 (IL-6), and heat shock protein 60 (HSPD1 (show HSPD1 Antibodies)), with breast cancer risk and survival in a Chinese Han population, was evaluated.

Cow (Bovine) Interleukin 6 (IL6) interaction partners

  1. when a confluent endometrial epithelial cell barrier is faced with infection and damage, chemokines attract immune cells to the uterine lumen, but IL6 is solely secreted apically to ensure immune cells are only exposed to IL6 once they reach the lumen.

  2. The results revealed that the peak expression of IL6 and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.

  3. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2 (show PTGS2 Antibodies), and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2 (show DAB2 Antibodies), and NR3C1 (show NR3C1 Antibodies). TNF (show TNF Antibodies) and IL6 levels were also decreased while those of NAMPT (show NAMPT Antibodies) were unaffected.

  4. Testicular IL-1 alpha (show IL1A Antibodies) and IL-1 beta (show IL1B Antibodies) concentrations were highest in the early post-natal period; however, IL-1 (show IL1A Antibodies) bioactivity and IL-6 concentrations were greatest in the immediate pre-pubertal period.

  5. The results showed that the expression of TNF-alpha (show TNF Antibodies), iNOS (show NOS2 Antibodies), and IL-6 in alveolar macrophages was up-regulated by stimulation with the recombinant Mce4A protein of M. bovis; in contrast, expression of IL-12 (show IL12A Antibodies) was unaffected.[IL-6, IL-12 (show IL12A Antibodies)]

  6. results show for the first time that interleukin-6 (IL6), in the presence of its soluble receptor (show IFNAR1 Antibodies) (sIL (show STIL Antibodies)-6R), induces activation of JAK1 (show JAK1 Antibodies), JAK2 (show JAK2 Antibodies), and STAT1 (show STAT1 Antibodies)/STAT3 (show STAT3 Antibodies) proteins in bovine articular chondrocytes.

  7. Mechanical injury potentiates the catabolic effects of TNFalpha (show TNF Antibodies) and IL-6/sIL (show STIL Antibodies)-6R in causing proteoglycan (show Vcan Antibodies) degradation in human and bovine cartilage.

Rabbit Interleukin 6 (IL6) interaction partners

  1. Mild heat shock increased the production of inflammatory cytokines, IL-1beta (show IL1B Antibodies) and IL-6 in rabbit cornea cells.

Pig (Porcine) Interleukin 6 (IL6) interaction partners

  1. we showed that IL-6 did not directly promote the proliferation of theca interna cells.

  2. Induction of ischemic osteonecrosis results in IL-6 production in the articular cartilage through an HIF-1 (show HIF1A Antibodies)-dependent pathway. IL-6 produced by hypoxic articular chondrocytes stimulates inflammatory cytokine responses in synovial cells.

  3. The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (show TGFB1 Antibodies), IL-10 (show IL10 Antibodies), and IL-6 in ovarian follicles are reported.

  4. Data suggest IL6 prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst viability via IL6/STAT3 (show STAT3 Antibodies) (signal transducer/activator of transcription (show STAT1 Antibodies) 3) signaling pathway (including up-regulation of STAT3 (show STAT3 Antibodies) expression/phosphorylation).

  5. LIF (show LIF Antibodies) and IL-6 are important components of embryo-uterine interactions during early pregnancy in the pig, and may contribute to successful conceptus implantation.

  6. INFgamma and IL-6 modulate PPARs gene expression in the porcine endometrium during the estrous cycle and pregnancy.

  7. interleukin-6, endothelin ET-1 (show EDN1 Antibodies), and apoptotic Bak (show BAK1 Antibodies) and Bcl-XL (show BCL2L1 Antibodies) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury

  8. Data show that all five molecules, BNP (show BNC2 Antibodies), ICAM-1 (show ICAM1 Antibodies), TNF-alpha (show TNF Antibodies), VCAM-1 (show VCAM1 Antibodies) and IL-6, quickly and reliably signaled adverse interactions.

  9. IL-6 level from frozen peripheral blood mononuclear cells was significantly lower than that from fresh ones.

  10. These results suggest that TNF-alpha (show TNF Antibodies) and IL-10 (show IL10 Antibodies), but not IL-6, are involved in the late reparatory phases of the experimental disk lesion.

Goat Interleukin 6 (IL6) interaction partners

  1. Plasma nitric oxide acts as a regulator of cytokine function exhibiting negative feedback to maintain steady plasma IL-6 concentration in protein- or energy-restricted goats during late gestation.

Horse (Equine) Interleukin 6 (IL6) interaction partners

  1. These data suggest that IL-6 may play a key role in equine metabolic syndrome (EMS), and that pro-inflammatory cytokines levels in serum may serve as an additional tool for diagnosing EMS.

  2. IL-6 stimulation decreased chondrocyte expression of the canonical Wnt (show WNT2 Antibodies) signaling pathway transactivator beta-catenin (show CTNNB1 Antibodies), induced expression of inhibitors of the Wnt (show WNT2 Antibodies) pathway, and increased expression of GDF-5 (show GDF5 Antibodies).

  3. study shows that IL-6 is rapidly induced in BAL-cells of airway-compromised horses in response to adenosine exposure, probably through A2BAR (show ADORA2B Antibodies) activation and that this effect can be modulated by A2AAR (show ADORA2A Antibodies)

  4. Our data show the presence of a polymorphism downstream of the equine IL-6 gene that is associated with the basal Cu:Zn ratio in horses independent of breed.

  5. Expression levels of IL-6 are significantly increased in peripheral blood mononuclear cells from trained horses compared to sedentary animals.

  6. Failure of passive transfer may directly influence the serum IL-6 concentration in septic foals. Neither serum IL-6 nor IL-10 (show IL10 Antibodies) alone, were useful diagnostic indices of sepsis in equine neonates.

  7. The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6, IL-10 (show IL10 Antibodies) and TNF-alpha (show TNF Antibodies), in horses with recurrent airway obstruction during exacerbation and in remission is reported.

Rainbow Trout (Oncorhynchus mykiss) Interleukin 6 (IL6) interaction partners

  1. IL6 mRNA abundance was significantly increased in spleen, liver, and gill of rainbow trout after experimental infection with Aeromonas salmonicida.

  2. in this paper we present for the first time in fish the functional characterisation of IL-6, using rainbow trout

  3. found that peptidoglycans derived from Gram-negative bacteria (Escherichia coli 0111:B4 and K12 (show KRT12 Antibodies)), are potent inducers of IL-1beta (show IL1B Antibodies) and IL-6 gene expression and were equal to, or more potent than, crude LPS (show IRF6 Antibodies).

Interleukin 6 (IL6) Antigen Profile

Protein Summary

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity).

Gene names and symbols associated with anti-Interleukin 6 (IL6) Antibodies

  • interleukin-6 (il-6) antibody
  • il6 antibody
GENE ID SPECIES
503562 Takifugu rubripes
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