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Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) ELISA Kits

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Additionally we are shipping IDH1 Antibodies (154) and IDH1 Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
IDH1 3417 O75874
IDH1 15926 O88844
IDH1 24479 P41562
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Top IDH1 ELISA Kits at

Showing 6 out of 13 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 1.33 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 9 to 11 Days
Rat 1.35 ng/mL 3.13-200 ng/mL 96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days
0.69-500 ng/mL   96 Tests Log in to see 9 to 19 Days

Top referenced IDH1 ELISA Kits

  1. Human IDH1 ELISA Kit for Sandwich ELISA - ABIN423443 : Tan, Jiang, Sun, Chen, Lv, Shao, Li, Qiu, Gao, Li, Tan, Zhou, Wang, Ding, Wang, Sun, Hang, Shi, Feng, He, He: Identification of isocitrate dehydrogenase 1 as a potential diagnostic and prognostic biomarker for non-small cell lung cancer by proteomic analysis. in Molecular & cellular proteomics : MCP 2012 (PubMed)
    Show all 3 references for ABIN423443

More ELISA Kits for IDH1 Interaction Partners

Human Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) interaction partners

  1. Data indicate that isocitrate dehydrogenase (NADP(+)) 1 (IDH1) mutation is a positive prognostic marker for low-grade glioma patients.

  2. Mutations in IDH1 gene conferred resistance to Temozolomide in glioblastoma.

  3. The combined use of IDH1 mutation and MGMT (show MGMT ELISA Kits) methylation status can be used as prognostic markers for long-term survival of patients with cerebral low-grade glioma.

  4. mmunohistochemistry can be used for evaluation of ATRX (show ATRX ELISA Kits) loss, p53 (show TP53 ELISA Kits) protein accumulation and IDH1R132H mutation, which may allow a means of classification of astrocytoma outcome

  5. Mutations in isocitrate dehydrogenase 1 with high d-2-hydroxyglutarate serum levels are associated with acute myeloid leukemia (show BCL11A ELISA Kits).

  6. IDH1 mutations are associated with myelodysplastic syndromes.

  7. With the advent of large-scale genome sequencing technology, molecular genetic alterations in IDH1 promoter have now been identified in the majority of oligodendrogliomas

  8. Mutant IDH1 R132H decreased cell proliferation of U87 glioma cells by inducing the expression of the miRNA miR128a.

  9. treatment with a cell-permeable form of 2-HG sensitized wild-type IDH1 AML (show RUNX1 ELISA Kits) cells to ATRA-induced myeloid differentiation, whereas inhibition of 2-HG production significantly reduced ATRA effects in mutant IDH1 cells.

  10. Classification based on IDH1/2 mutation status and Ki-67 (show MKI67 ELISA Kits) expression level could be more convenient for clinical application and guide personalized treatment in malignant gliomas.

Mouse (Murine) Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) interaction partners

  1. data suggest that mutant IDH1 contributes to malignancy in the T-cell lineage and may alter the metabolic profile of malignant T cells

  2. The results suggest that Idh1 has a physiological function in protecting cells from oxidative stress by regulating the intracellular NADP(+)/NADPH (show FDXR ELISA Kits) ratio.

  3. These results support the translational potential of immunotherapeutic targeting of gliomas carrying IDH1 mutations R132H.

  4. MiR (show MLXIP ELISA Kits)-181a regulates lipid metabolism via IDH1

  5. revealed a role for IDH1 in the synthesis/turnover of phospholipids in developing astrocytes and highlight the lipid alterations resulting from the loss of wild-type IDH1 activity.

  6. these data show that mutant IDH or d-2HG causes persistence of chondrocytes, giving rise to rests of growth-plate cells that persist in the bone as enchondromas.

  7. WA might exert its chemopreventive activity via inhibiting not only oncogenic activation, but also IDH1 inactivation.

  8. Brain-specific (show CALY ELISA Kits) Idh1-KI mice show brain hemorrhage accompanied by high D2HG levels but decreased ROS (show ROS1 ELISA Kits)

  9. Suggest that decreased IDPc expression renders melanocytes more vulnerable to oxidative stress, and IDPc plays an important antioxidant function in melanocytes.

  10. Absence of IDH1 mutations in low-grade gliomas (LGGs) identifies a novel entity of LGGs with distinctive location, infiltrative behavior, specific molecular alterations, and dismal outcome.

Cow (Bovine) Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) interaction partners

  1. Data suggest that the expression of cytosolic NADP+-dependent isocitrate dehydrogenase in bovine mammary epithelium is modulated by regulators of differentiation including extracellular matrix and lactogenic hormones as well as metabolic effectors.

Pig (Porcine) Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) interaction partners

  1. Tyr140 and Lys212 are required for the catalytic activity of porcine NADP-dependent isocitrate dehydrogenase (show IDH3B ELISA Kits)

  2. analysis of the coenzyme binding site in the porcine mitochondrial NADP-dependent isocitrate dehydrogenase (show IDH3B ELISA Kits)

  3. These results suggest that IDPm (show IDH2 ELISA Kits) plays an important protective role in cadmium-induced apoptosis by maintaining cellular redox status and by protection of Grx (show GRX1 ELISA Kits) activity.

IDH1 Antigen Profile

Antigen Summary

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.

Gene names and symbols associated with IDH1

  • isocitrate dehydrogenase 1 (NADP+), soluble (IDH1) antibody
  • isocitrate dehydrogenase 1 (NADP+), soluble (Idh1) antibody
  • isocitrate dehydrogenase 1 (NADP+), soluble (idh1) antibody
  • isocitrate dehydrogenase 2 (NADP+), mitochondrial (IDH2) antibody
  • AI314845 antibody
  • AI788952 antibody
  • cb876 antibody
  • E030024J03Rik antibody
  • fm90e09 antibody
  • Id-1 antibody
  • IDCD antibody
  • IDH antibody
  • Idh-1 antibody
  • IDP antibody
  • Idpc antibody
  • im:7143416 antibody
  • NADP-CICDH antibody
  • PICD antibody
  • wu:fm90e09 antibody

Protein level used designations for IDH1

isocitrate dehydrogenase 1 (NADP+), soluble , isocitrate dehydrogenase [NADP] cytoplasmic-like , NADP(+)-specific ICDH , NADP-dependent isocitrate dehydrogenase, cytosolic , NADP-dependent isocitrate dehydrogenase, peroxisomal , isocitrate dehydrogenase [NADP] cytoplasmic , oxalosuccinate decarboxylase , IDH , IDP , cytosolic NADP-isocitrate dehydrogenase , isocitrate dehydrogenase 1 , Isocitrate dehydrogenase 1, soluble , ICD-M , NADPH-specific isocitrate dehydrogenase , isocitrate dehydrogenase [NADP], mitochondrial

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397603 Sus scrofa
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