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Receptor on natural killer (NK) cells for class I MHC.. Additionally we are shipping Klra7 Antibodies (9) and many more products for this protein.
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The ectodomain of inhibitory Ly49G of the BALB/c mouse strain is highly similar to the Ly49W activating receptor in the nonobese diabetic (NOD) mouse.
The repertoire of inhibitory Ly49 receptors may be formed under the influenced of Fyn-dependent NK cell activation as well as the respective MHC class I environment.
Allelic variation in Ly-49G2 extracellular domains has functional significance by altering Ly-49 receptor specificity for class I MHC and xenogeneic ligands.
Glycosylation of Ly-49G2 at amino acid residues NTT221-23 reduces receptor binding to H-2Dd (show DHDH Proteins) tetramers and may represent a mechanism by which natural killer cells regulate affinity for host class I ligands.
High levels of Ly49G2 have a dominant inhibitory effect on Ly49D expressed at low levels on immature bone marrow and mature B cells, resulting in inhibition of interferon-gamma (show IFNG Proteins) secretion.
Receptor on natural killer (NK) cells for class I MHC.
T-cell surface glycoprotein Ly-49G
, killer cell lectin-like receptor 7
, lymphocyte antigen 49g
, immunoreceptor Ly49si3-like