Kinesin Family Member 11 Proteins (KIF11)

KIF11 encodes a motor protein that belongs to the kinesin-like protein family. Additionally we are shipping KIF11 Antibodies (123) and KIF11 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KIF11 3832 P52732
KIF11 16551 Q6P9P6
Rat KIF11 KIF11 171304  
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Top KIF11 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details

KIF11 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Top referenced KIF11 Proteins

  1. Human KIF11 Protein expressed in HEK-293 Cells - ABIN2724227 : Drosopoulos, Tang, Chao, Linardopoulos: APC/C is an essential regulator of centrosome clustering. in Nature communications 2014 (PubMed)

More Proteins for Kinesin Family Member 11 (KIF11) Interaction Partners

Human Kinesin Family Member 11 (KIF11) interaction partners

  1. Progressive retinal degeneration in KIF11-related retinopathy indicates a role for KIF11 not only in ocular development but also in maintaining retinal morphology and function. The remarkable variability of the ocular phenotype suggests four different types of retinopathy which may overlap.

  2. Among the detected mutations, LRP5 (show LRP5 Proteins) accounted for the largest proportion with a mean mutation rate of 16.1% (5/31, 16.1%), followed by NDP (show NDP Proteins) (3/31, 9.7%), FZD4 (show FZD4 Proteins) (2/31, 6.5%), TSPAN12 (show TSPAN12 Proteins) (1/31, 3.2%), and KIF11 (1/31, 3.2%). All the novel changes were predicted to be pathogenic by a series of bioinformatics analyses.

  3. Data show that the kinesin 5 (Eg5) binding time has less sensitivity on MCF7 as compared to bovine brain microtubules.

  4. mixing of Eg5 and MTs (show TIMM8A Proteins) produced a range of spatiotemporal dynamics

  5. that Pten, through the Dlg1 (show DLG1 Proteins)-binding ability of its PDZ-binding domain , accumulates phosphorylated Eg5 at duplicated centrosomes to establish symmetrical bipolar spindles that properly segregate chromosomes

  6. KIF11 is an important regulator of activity in oesophageal and colorectal tumor stem cells.

  7. Levels of phosphorylated Erk1/2 were lower in KIF11 siRNA-transfected cells than with negative-control siRNA-transfected cells. These results indicate that KIF11 is involved in intestinal mucin (show SLC13A2 Proteins) phenotype gastric cancer.

  8. Patients with KIF11 mutations show a specific ocular phenotype with variable expressivity and intrafamilial variability. Macular atrophy and dysfunction have not been consistently documented before.

  9. This stuidy demonstrated that overexpression of Eg5 associates with high-grade astrocytic neoplasm.

  10. Data show that kinesin spindle protein Eg5 inhibitor LY2523355 has broad target-mediated anticancer activity in vitro and in vivo.

Pig (Porcine) Kinesin Family Member 11 (KIF11) interaction partners

  1. Data suggest that poleward transport of TPX2, which requires dynein and Eg5, down-regulates its microtubule nucleating activity near kinetochores and links microtubules to dynein for incorporation into the spindle.

Mouse (Murine) Kinesin Family Member 11 (KIF11) interaction partners

  1. that Pten, through the Dlg1 (show DLG1 Proteins)-binding ability of its PDZ-binding domain , accumulates phosphorylated Eg5 at duplicated centrosomes to establish symmetrical bipolar spindles that properly segregate chromosomes

  2. Fbxo30 (show FBXO30 Proteins)-Eg5 interaction as a critical checkpoint in mammopoiesis.

  3. Data show that the STIM1 (show STIM1 Proteins) Ksp (Eg5)-cre knockout mice produced more urine compared to control.

  4. Data suggest that amyloid-beta (here, Abeta 1-42) induces acute and chronic synaptic dysfunction in part through inhibition of Eg5 (kinesin-5) in hippocampal neurons.

  5. Disruption of the in vivo interaction of KIF11 with ZBP1 (show ZBP1 Proteins) delocalizes beta-actin (show ACTB Proteins) mRNA and affects cell migration.

  6. These results suggest that 4-(N-(2-(N-acetylcysteine-S-yl) acetyl) amino)-4'- (N-(2-(N-(triphenylmethyl)amino)acetyl)amino)azobenzene could be used as photochromic inhibitor of Eg5 to achieve photocontrol of living cells.

  7. incorporation of photochromic molecules into the key region of loop L5 facilitates the photocontrol of the function of kinesin Eg5.

  8. Finally, when kinesin spindle protein (KSP) siRNA was encapsulated in lipid nanoparticles containing a modest amount of PEG (show PAEP Proteins), the proliferation of endothelial cells was inhibited due to the efficient knock down of KSP mRNA.

  9. These results show that intratumoral electro-transfer of siRNA is feasible and kinesin spindle protein (KSP)-specific siRNA may provide a novel strategy for therapeutic intervention.

  10. observations explain the poleward accumulation of Eg5 in early mitosis and its redistribution in anaphase. Inhibition of dynein blocked Eg5 movement on microtubules, whereas depletion of the Eg5-binding protein TPX2 (show DAZL Proteins) resulted in end-directed Eg5 movement.

Cow (Bovine) Kinesin Family Member 11 (KIF11) interaction partners

  1. Data show that the kinesin 5 (Eg5) binding time has less sensitivity on MCF7 as compared to bovine brain microtubules.

KIF11 Protein Profile

Protein Summary

This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.

Gene names and symbols associated with KIF11

  • kinesin family protein (AT2G36200)
  • kinesin family member 11 (kif11)
  • kinesin family member 11 (KIF11)
  • kinesin family member 11 (Kif11)
  • DDBDRAFT_0189194 protein
  • DDBDRAFT_0201556 protein
  • DDB_0189194 protein
  • DDB_0201556 protein
  • Eg5 protein
  • F2H17.19 protein
  • F2H17_19 protein
  • HKSP protein
  • Kif8 protein
  • Kifl1 protein
  • Knsl1 protein
  • MCLMR protein
  • TRIP5 protein

Protein level used designations for KIF11

TR-interacting protein 5 , TRIP-5 , kinesin-like protein 1 , kinesin-like protein KIF11 , kinesin-like spindle protein HKSP , kinesin-related motor protein Eg5 , thyroid receptor-interacting protein 5 , kinesin 11 , kinesin-like 1

GENE ID SPECIES
818192 Arabidopsis thaliana
8627935 Dictyostelium discoideum AX4
3832 Homo sapiens
100526080 Sus scrofa
16551 Mus musculus
171304 Rattus norvegicus
423809 Gallus gallus
477769 Canis lupus familiaris
508467 Bos taurus
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