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Kruppel-Like Factor 2 (Lung) Proteins (KLF2)

Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. Additionally we are shipping KLF2 Antibodies (94) and KLF2 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KLF2 10365 Q9Y5W3
KLF2 16598 Q60843
KLF2 306330 Q9ET58
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Top KLF2 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,955.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

KLF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Kruppel-Like Factor 2 (Lung) (KLF2) Interaction Partners

Human Kruppel-Like Factor 2 (Lung) (KLF2) interaction partners

  1. Authors show that KLF2 induces the expression of CRABP2 (show CRABP2 Proteins) and RARgamma and inhibits the expression FABP5 (show FABP5 Proteins) and PPARbeta (show PPARD Proteins)/delta thereby shifting RA signaling from the pro-carcinogenic FABP5 (show FABP5 Proteins)/PPARbeta (show PPARD Proteins)/delta to the growth-suppressing CRABP2 (show CRABP2 Proteins)/RAR (show RARA Proteins) path.

  2. MicroRNA-30 mediates anti-inflammatory effects of shear stress and KLF2 via repression of Ang2.

  3. In hyperuricemia, miR (show MLXIP Proteins)-92a downregulation increased KLF2 expression, subsequently inhibiting VEGFA (show VEGFA Proteins), which resulted in decreased angiogenesis.

  4. These data provide support for a continuous role of KLF2 in stabilizing the vessel wall via co-temporal expression of eNOS and AQP1 both preceding and during the pathogenesis of atherosclerosis.

  5. These results indicate that the KDM3A (show KDM3A Proteins)-KLF2-IRF4 (show IRF4 Proteins) pathway plays an essential role in multiple myeloma cell survival and homing to the bone marrow, and therefore represents a therapeutic target.

  6. Expression of KLF4 (show KLF4 Proteins) in mononuclear leukocytes positively correlates with cellular markers of immune activation, whereas KLF2 expression negatively correlates with markers of subclinical atherosclerosis in this HIV-infected population.

  7. TUG1 overexpression was induced by nuclear transcription factor SP1 (show SP1 Proteins) and TUG1 could epigeneticly repress Kruppel-like factor 2 (KLF2) transcription in HCC (show FAM126A Proteins) cells by binding with PRC2 and recruiting it to KLF2 promoter region.

  8. studies identify gain of MEKK3 sig (show MAP3K3 Proteins)nalling and KL (show KLF4 Proteins)F2/4 function as causal mechanisms for cerebral cavernous malformations pathogenesis that may be targeted to develop new CCM therapeutics

  9. In conclusion, KLF2 suppressed the angiogenesis of LSECs through inhibition of cell proliferation, migration, and vessel tube formation.

  10. TINCR could bind to STAU1 (staufen1 (show STAU1 Proteins)) protein, and influence KLF2 mRNA stability and expression

Pig (Porcine) Kruppel-Like Factor 2 (Lung) (KLF2) interaction partners

  1. miR (show MYLIP Proteins)-92a coregulates KLF4 (show KLF4 Proteins) and KLF2 expression in arterial endothelium and contributes to phenotype heterogeneity associated with regional atherosusceptibility and protection in vivo.

Mouse (Murine) Kruppel-Like Factor 2 (Lung) (KLF2) interaction partners

  1. KLF2 knockdown markedly reduced expression of miR (show MLXIP Proteins)-155 in macrophages and macrophage activation.

  2. study therefore establishes the pivotal role of Klf2 and Tfcp2l1 (show TFCP2L1 Proteins) in mediating ESC self-renewal promoted by Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling.

  3. endothelial-specific loss of Mekk3 (show MAP3K3 Proteins), Klf2 or Klf4 (show KLF4 Proteins) markedly prevents cerebral cavernous malformation lesion formation, reverses the increase in Rho activity, and rescues lethality

  4. knockdown of Klf2 expression in endothelial cells induced more endothelial cell injury in early diabetic nephropathy

  5. Cineromycin B inhibited adipocyte differentiation in 3T3-L1 cells mainly via upregulation of KLF2 and KLF3 (show KLF3 Proteins) mRNA expression at an early stage of the differentiation.

  6. Data reveal a novel role of HDAC5 (show HDAC5 Proteins) in modulating the KLF2 transcriptional activation and eNOS (show NOS3 Proteins) expression.

  7. inhibition of leukocyte adhesion by Myocyte enhancer factor 2 C was partially mediated by induction of KLF2

  8. KLF2 is pivotal for coordinating CD4 (show CD4 Proteins)(+) T cell differentiation through two distinct and complementary mechanisms: via control of T cell localization and by regulation of lineage-defining transcription factors.

  9. The Kruppel-like factor 2 (Klf2) is phosphorylated by Erk2 (show MAPK1 Proteins) and that phospho-Klf2 is proteosomally degraded.

  10. reveals a beta1 integrin-Klf2-Egfl7 (show EGFL7 Proteins)-signaling pathway that is tightly regulated by cerebral cavernous malformation proteins

Xenopus laevis Kruppel-Like Factor 2 (Lung) (KLF2) interaction partners

  1. KLF2 and ERG (show ERG Proteins) associate in a physical complex and the two proteins synergistically activate transcription of Flk1 (show KDR Proteins).

KLF2 Protein Profile

Protein Summary

Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1\; MIM 601974) and the selectin CD62L (SELL\; MIM 153240) (summary by Weinreich et al., 2009

Gene names and symbols associated with KLF2

  • Kruppel-like factor 2 (lung) (klf2)
  • Krueppel-like factor 2 (klf2)
  • Kruppel-like factor 2 (lung) (KLF2)
  • Kruppel-like factor 2 (lung) (Klf2)
  • klf2 protein
  • Lklf protein
  • MGC52512 protein

Protein level used designations for KLF2

Kruppel-like factor 2 (lung) , Krueppel-like factor 2 , Kruppel-like factor LKLF , lung Kruppel-like zinc finger transcription factor , lung krueppel-like factor , lung Kruppel-like factor

GENE ID SPECIES
549518 Xenopus (Silurana) tropicalis
100286404 Salmo salar
100586551 Nomascus leucogenys
10365 Homo sapiens
100174959 Sus scrofa
16598 Mus musculus
306330 Rattus norvegicus
420148 Gallus gallus
380122 Xenopus laevis
520939 Bos taurus
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