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Kruppel-Like Factor 5 (Intestinal) Proteins (KLF5)

KLF5 encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Additionally we are shipping KLF5 Antibodies (66) and KLF5 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat KLF5 KLF5 84410  
KLF5 12224 Q9Z0Z7
KLF5 688 Q13887
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Top KLF5 Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 11 to 13 Days

KLF5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Kruppel-Like Factor 5 (Intestinal) (KLF5) Interaction Partners

Mouse (Murine) Kruppel-Like Factor 5 (Intestinal) (KLF5) interaction partners

  1. Data show that R-Smad Proteins SMAD1 and SMAD5, which transduce bone morphogenetic protein (BMP) signals, recognize enhancer regions together with Kruppel-like factors KLF4 and KLF5 in naive embryonic stem cell (mESCs).

  2. illustrates that KLF5 may modulate DNA repair pathways to prevent intestinal injury induced by TBI (show TBPL1 Proteins). KLF5 signaling provides a novel field for identification of potential therapeutic targets for the treatment of radiation-induced intestinal damage

  3. Cardiac myocyte KLF5 is a transcriptional regulator of Ppara (show PPARA Proteins) and cardiac energetics.

  4. In embryonic stem cells, we show that Klf5, but not JunB (show JUNB Proteins) is a key LIF (show LIF Proteins) effector of cell plasticity.

  5. the regulatory functions of Klf5 acetylation in ESC self-renewal and differentiation

  6. unravels a novel mechanism how matrix stiffness regulates cellular proliferation and highlights the importance of matrix stiffness-modulated Klf5/Klf4 (show KLF4 Proteins) in the regulation of renal physiologic functions and fibrosis progression

  7. that estrogen biphasically modulates prostate tumor formation by regulating Kruppel-like zinc finger transcription factor (show OSR1 Proteins) 5 (show CEBPB Proteins)-dependent transcription through estrogen receptor beta (show ESR2 Proteins)

  8. KLF5 loss enhances tumor angiogenesis by attenuating PI3K/AKT signaling and subsequent accumulation of HIF1alpha in PTEN deficient prostate tumors.

  9. Simultaneous downregulation of KLF5 and Fli1 (show FLI1 Proteins) is a key feature underlying systemic sclerosis.

  10. TMEM16A (show ANO1 Proteins) and myocardin form a positive feedback loop that is disrupted by KLF5 during Ang II (show AGT Proteins)-induced vascular remodeling.

Human Kruppel-Like Factor 5 (Intestinal) (KLF5) interaction partners

  1. demonstrate that a 186bp region is the minimal essential region and that Sp3-GC1 (show OLFM4 Proteins) binding is essential to the basal expression of KLF5

  2. We provide the first evidence that the expression of KLF5 is up-regulated in small airways and pulmonary vessels of patients with COPD (show ARCN1 Proteins) and may be involved in the tissue remodeling of COPD (show ARCN1 Proteins).

  3. our results indicate that KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA (show VEGFA Proteins) transcription

  4. Data indicate direct binding of microRNA miR (show MLXIP Proteins)-375 to the 3'-untranslated region of transcription factor KLF5.

  5. findings collectively suggest that TNFAIP2 (show TNFAIP2 Proteins) is a direct KLF5 target gene, and both KLF5 and TNFAIP2 (show TNFAIP2 Proteins) promote breast cancer cell proliferation, migration and invasion through Rac1 and Cdc42 (show CDC42 Proteins)

  6. ABL (show ABL1 Proteins)-N administration induced apoptosis of PC3 (show PCSK1 Proteins) cells in a dose-dependent manner, along with the enhanced activity of caspases and increased Bax (show BAX Proteins)/Bcl-2 (show BCL2 Proteins) ratio. Expression of KLF5, Stat5b (show STAT5B Proteins) and ICAM-1 (show ICAM1 Proteins) was significantly downregulated in PC3 (show PCSK1 Proteins) cells.

  7. KLF5/Sox4 regulatory signaling play an important role in lung tumorigenesis, which might represent novel therapeutic targets to manage lung carcinoma.

  8. BAP1 (show RNF2 Proteins) interacts directly with KLF5 and stabilizes KLF5 via deubiquitination.

  9. Data suggest both KLF5 and FYN (FYN proto-oncogene) are important in regulation of migration in bladder cancer cells; KLF5 up-regulates cell migration, lamellipodia formation, expression of FYN, and phosphorylation of FAK (focal adhesion kinase).

  10. ATXN3L has a role in the regulation of KLF5 stability in breast cancer

KLF5 Protein Profile

Protein Summary

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.

Gene names and symbols associated with KLF5

  • Kruppel-like factor 5 (intestinal) (KLF5)
  • Kruppel-like factor 5 (intestinal) (LOC100231095)
  • Kruppel-like factor 5 (klf5)
  • Kruppel-like factor 5 (Klf5)
  • 4930520J07Rik protein
  • bteb2 protein
  • CKLF protein
  • IKLF protein
  • klf5 protein
  • MGC115081 protein

Protein level used designations for KLF5

Kruppel-like factor 5 (intestinal) , Krueppel-like factor 5-like , Kruppel-like factor 5 , basic-transcription-element-binding-protein 2 , basic transcription element binding protein 2 , basic transcription element binding protein BTEB2 , BTE-binding protein 2 , Krueppel-like factor 5 , basic transcription element-binding protein 2 , intestinal-enriched krueppel-like factor , transcription factor BTEB2 , GC box binding protein 2 , GC-box-binding protein 2 , colon krueppel-like factor , colon kruppel-like factor , intestinal-enriched kruppel-like factor

100052058 Equus caballus
452597 Pan troglodytes
100010455 Monodelphis domestica
100231095 Taeniopygia guttata
100467044 Ailuropoda melanoleuca
100607414 Nomascus leucogenys
735138 Xenopus laevis
100008718 Oryctolagus cuniculus
84410 Rattus norvegicus
12224 Mus musculus
688 Homo sapiens
418818 Gallus gallus
612788 Canis lupus familiaris
100038005 Sus scrofa
535702 Bos taurus
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