Kruppel-Like Factor 5 (Intestinal) Proteins (KLF5)

KLF5 encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Additionally we are shipping KLF5 Antibodies (70) and KLF5 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat KLF5 KLF5 84410  
KLF5 12224 Q9Z0Z7
KLF5 688 Q13887
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Top KLF5 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 6 to 10 Days
$259.00
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$648.00
Details

KLF5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Kruppel-Like Factor 5 (Intestinal) (KLF5) Interaction Partners

Mouse (Murine) Kruppel-Like Factor 5 (Intestinal) (KLF5) interaction partners

  1. KLF5 regulates intestinal barrier function by mediating the transcription of DSG2 (show DSG2 Proteins), a gene encoding a major component of desmosome structures

  2. Klf5 suppresses Fgf4 (show FGF4 Proteins)-Fgfr (show FGFR2 Proteins)-ERK (show EPHB2 Proteins) signalling, thus preventing precocious activation of the primitive endoderm specification programme

  3. In conclusion, the results of this study suggest that the presence of KLF5 in postn (show POSTN Proteins)-positive cells contributes to the pathogenesis of aortic thickening induced by DOCA-salt hypertension.

  4. these studies demonstrate dual functions of Klf5 in regulating hematopoietic stem and progenitor proliferation and localization in the bone marrow, as well as lineage choice after GMP (show NT5C2 Proteins), promoting increased neutrophil output at the expense of eosinophil production.

  5. Collectively, we identify a novel regulatory pathway in which 1, 25(OH)2D3 induces VDR (show CYP27B1 Proteins) expression and promotes VDR (show CYP27B1 Proteins) interaction with p50 subunit of NF-kappaB (show NFKB1 Proteins), which in turn attenuates the association of KLF5 with p50 subunit of NF-kappaB (show NFKB1 Proteins) and thus exerts anti-inflammatory and anti-proliferative effects on macrophages.

  6. KLF5-dependent regulation of Myo9b/RhoA (show RHOA Proteins) is required for podosome formation and macrophage migration during abdominal aortic aneurysm.

  7. Data show that R-Smad Proteins SMAD1 and SMAD5, which transduce bone morphogenetic protein (BMP) signals, recognize enhancer regions together with Kruppel-like factors KLF4 and KLF5 in naive embryonic stem cell (mESCs).

  8. illustrates that KLF5 may modulate DNA repair pathways to prevent intestinal injury induced by TBI. KLF5 signaling provides a novel field for identification of potential therapeutic targets for the treatment of radiation-induced intestinal damage

  9. Cardiac myocyte KLF5 is a transcriptional regulator of Ppara (show PPARA Proteins) and cardiac energetics.

  10. In embryonic stem cells, we show that Klf5, but not JunB (show JUNB Proteins) is a key LIF (show LIF Proteins) effector of cell plasticity.

Human Kruppel-Like Factor 5 (Intestinal) (KLF5) interaction partners

  1. miR (show MLXIP Proteins)-217 suppresses triple-negative breast cancer cell growth, migration, and invasion. MiR (show MLXIP Proteins)-217 suppresses triple-negative breast cancer, at least partially, through down-regulating the KLF5 expression.

  2. Data reveal that the presence of rs200996365, a SNP in high-linkage disequilibrium with rs8102137 residing in the center of a KLF5 motif, alters KLF5 binding to this genomic region and provide evidence that KLF5 binds CCNE1 (show CCNE1 Proteins) polymorphic intronic enhancer to confer increased bladder cancer risk.

  3. demonstrate that a 186bp region is the minimal essential region and that Sp3-GC1 (show OLFM4 Proteins) binding is essential to the basal expression of KLF5

  4. We provide the first evidence that the expression of KLF5 is up-regulated in small airways and pulmonary vessels of patients with COPD (show ARCN1 Proteins) and may be involved in the tissue remodeling of COPD (show ARCN1 Proteins).

  5. our results indicate that KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA (show VEGFA Proteins) transcription

  6. Data indicate direct binding of microRNA miR (show MLXIP Proteins)-375 to the 3'-untranslated region of transcription factor KLF5.

  7. findings collectively suggest that TNFAIP2 (show TNFAIP2 Proteins) is a direct KLF5 target gene, and both KLF5 and TNFAIP2 (show TNFAIP2 Proteins) promote breast cancer cell proliferation, migration and invasion through Rac1 and Cdc42 (show CDC42 Proteins)

  8. ABL (show ABL1 Proteins)-N administration induced apoptosis of PC3 (show PCSK1 Proteins) cells in a dose-dependent manner, along with the enhanced activity of caspases and increased Bax (show BAX Proteins)/Bcl-2 (show BCL2 Proteins) ratio. Expression of KLF5, Stat5b (show STAT5B Proteins) and ICAM-1 (show ICAM1 Proteins) was significantly downregulated in PC3 (show PCSK1 Proteins) cells.

  9. KLF5/Sox4 regulatory signaling play an important role in lung tumorigenesis, which might represent novel therapeutic targets to manage lung carcinoma.

  10. BAP1 (show RNF2 Proteins) interacts directly with KLF5 and stabilizes KLF5 via deubiquitination.

KLF5 Protein Profile

Protein Summary

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.

Gene names and symbols associated with KLF5

  • Kruppel like factor 5 (KLF5)
  • Kruppel-like factor 5 (intestinal) S homeolog (klf5.S)
  • Kruppel-like factor 5 (Klf5)
  • 4930520J07Rik protein
  • bteb2 protein
  • CKLF protein
  • IKLF protein
  • klf5 protein
  • MGC115081 protein

Protein level used designations for KLF5

Kruppel-like factor 5 (intestinal) , Krueppel-like factor 5-like , Kruppel-like factor 5 , basic-transcription-element-binding-protein 2 , basic transcription element binding protein 2 , basic transcription element binding protein BTEB2 , BTE-binding protein 2 , Krueppel-like factor 5 , basic transcription element-binding protein 2 , intestinal-enriched krueppel-like factor , transcription factor BTEB2 , GC box binding protein 2 , GC-box-binding protein 2 , colon krueppel-like factor , colon kruppel-like factor , intestinal-enriched kruppel-like factor

GENE ID SPECIES
100052058 Equus caballus
452597 Pan troglodytes
100010455 Monodelphis domestica
100231095 Taeniopygia guttata
100467044 Ailuropoda melanoleuca
100607414 Nomascus leucogenys
735138 Xenopus laevis
100008718 Oryctolagus cuniculus
84410 Rattus norvegicus
12224 Mus musculus
688 Homo sapiens
418818 Gallus gallus
612788 Canis lupus familiaris
100038005 Sus scrofa
535702 Bos taurus
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