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LAG1 Homolog, Ceramide Synthase 2 (LASS2) ELISA Kits

LASS2 encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Additionally we are shipping and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LASS2 29956 Q96G23
Anti-Mouse LASS2 LASS2 76893 Q924Z4
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Top LAG1 Homolog, Ceramide Synthase 2 ELISA Kits at

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.058 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days

More ELISA Kits for LAG1 Homolog, Ceramide Synthase 2 Interaction Partners

Human LAG1 Homolog, Ceramide Synthase 2 (LASS2) interaction partners

  1. Data show that 1-acylglycerol-3-phosphate O-acyltransferase 9 (AGPAT9 (show AGPAT9 ELISA Kits)) inhibit cell growth by regulating expression of KLF4 (show KLF4 ELISA Kits)/LASS2 (show CERS2 ELISA Kits)/V-ATPase (show ATP6V1H ELISA Kits) proteins in breast cancer.

  2. these results indicate that miR (show MLXIP ELISA Kits)-9 upregulation might be associated with malignant phenotype of bladder cancer. miR (show MLXIP ELISA Kits)-9 promotes chemoresistance of bladder cancer cells by target LASS2 (show CERS2 ELISA Kits).

  3. Data show that CERS2 (show CERS2 ELISA Kits) expression was markedly different between various breast cancer cells and inversely correlated with cell invasion.

  4. silencing of TMSG1 increased V-ATPase (show ATP6V1H ELISA Kits) activity, decreased extracellular pH and in turn the activation of secreted MMP-2 (show MMP2 ELISA Kits), which ultimately promoted metastasis capacity of breast cancer cell.

  5. Results confirmed that TMSG1 is a potential metastasis suppressor gene, and suggested that the mechanism involved the induction of apoptosis and inhibition of cell proliferation via a caspase (show CASP3 ELISA Kits)-dependent mitochondrial pathway.

  6. the vacuolar ATPase (V-ATPase (show DNAH8 ELISA Kits)) activity and extracellular hydrogen ion concentration were significantly decreased and the activity of secreted matrix metalloproteinase-2 (MMP-2 (show MMP2 ELISA Kits)) was downregulated in MCF-7 cells overexpressing LASS2/TMSG1

  7. the inhibitory effect of the LASS2 (show CERS2 ELISA Kits) on growth, invasion and metastasis of prostate cancer cells

  8. Co-expression of CerS2 with CerS4/CerS6 reversed the inhibitory effect of long chain ceramides on cell proliferation and the induction of apoptosis. we detected no effect on cell proliferation.

  9. expression and role of ceramide synthase-2 (show CERS2 ELISA Kits) in the lung

  10. results contribute to the conclusion that LASS2/TMSG1 could regulate V-ATPase (show ATP6V1H ELISA Kits) activity and intracellular pH through the direct interaction of its homeodomain and the C subunit of V-ATPase (show ATP6V1H ELISA Kits)

Mouse (Murine) LAG1 Homolog, Ceramide Synthase 2 (LASS2) interaction partners

  1. that only LCBs, the substrates common for all of the CerS isoforms, but not ceramides and complex sphingolipids, were restored to the wild-type levels in the Cers2 (show CERS2 ELISA Kits)-rescued Cers1 (show CERS1 ELISA Kits) mutant mouse brains.

  2. CerS1 (show CERS1 ELISA Kits), -2, and -6 are hyperacetylated in the mitochondria of SIRT3 (show SIRT3 ELISA Kits)-null mice.

  3. Haploinsufficiency for this enzyme altered the pattern of ceramide acylation in the liver without affecting total ceramide levels, replacing very-long-chain ceramides with long-chain C16-ceramides.

  4. Development of pheochromocytoma in ceramide synthase 2 (show CERS2 ELISA Kits) null mice

  5. our data strongly indicate that G-CSF (show CSF3 ELISA Kits)-induced CXCR2 (show CXCR2 ELISA Kits) expression is regulated in a CerS2 (show CERS2 ELISA Kits)-dependent manner and that CerS2 (show CERS2 ELISA Kits) thereby promotes the migration of neutrophils, thus, contributing to inflammation and the development of EAE and MS.

  6. Data indicate that the augmented rate of death of ceramide synthase 2 (CerS2 (show CERS2 ELISA Kits)) null mice is due to elevated levels of tumor necrosis factor alpha (TNFalpha (show TNF ELISA Kits)) secretion as a result of enhanced activity of TNFalpha (show TNF ELISA Kits)-converting enzyme (TACE (show ADAM17 ELISA Kits)).

  7. CerS2 (show CERS2 ELISA Kits)-deficient kidneys were completely depleted of phytosphingosine-containing cortical sulfatides without any compensatio

  8. we first report that Lass2 (show CERS2 ELISA Kits) deficiency caused the downregulation of miR (show MLXIP ELISA Kits)-694 and the upregulation of its target gene Tnfaip3 (show TNFAIP3 ELISA Kits) in vivo in mice, which may be related to a high risk of occurrence of hepatocellular carcinoma

  9. The identification of specific cell types in which CerS2 (show CERS2 ELISA Kits) protein is expressed is prerequisite to further mechanistic characterization of phenotypic abnormalities exhibited by CerS2 (show CERS2 ELISA Kits)-deficient mice.

  10. Lass2 (show CERS2 ELISA Kits) is a protective gene against diethylnitrosamine-induced liver tumorigenesis; and upregulation of the TGF-beta1 (show TGFB1 ELISA Kits)-Smad4 (show SMAD4 ELISA Kits)-PAI-1 (show SERPINE1 ELISA Kits) axis may contribute to the vulnerability of Lass2 (show CERS2 ELISA Kits)-knockout mice to diethylnitrosamine.

LAG1 Homolog, Ceramide Synthase 2 (LASS2) Antigen Profile

Antigen Summary

This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.

Gene names and symbols associated with LASS2

  • ceramide synthase 2 (CERS2) antibody
  • ceramide synthase 2 (Cers2) antibody
  • 0610013I17Rik antibody
  • AI225939 antibody
  • L3 antibody
  • Lass2 antibody
  • SP260 antibody
  • TMSG1 antibody
  • TRH3 antibody

Protein level used designations for LASS2

LAG1 homolog, ceramide synthase 2 , LAG1 longevity assurance 2 , longevity assurance (LAG1, S. cerevisiae) homolog 2 , tumor metastasis-suppressor gene 1 protein , LAG1 longevity assurance homolog 2 , TRAM homolog 3 , longevity assurance homolog 2 , translocating chain-associating membrane protein homolog 3

29956 Homo sapiens
76893 Mus musculus
539223 Bos taurus
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