Leukocyte Specific Transcript 1 Proteins (LST1)

The protein encoded by LST1 is a membrane protein that can inhibit the proliferation of lymphocytes. Additionally we are shipping LST1 Antibodies (62) and LST1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LST1 7940 O00453
LST1 16988  
Rat LST1 LST1 64569  
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Top LST1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 20 Days

LST1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Leukocyte Specific Transcript 1 (LST1) Interaction Partners

Human Leukocyte Specific Transcript 1 (LST1) interaction partners

  1. Increased expression of LST1 (show NFKBIL1 Proteins) in GC-responders before therapy warrants further investigation into their role as potential predictors for the response to GC, and in the inflammatory process of rheumatoid arthritis.

  2. Data indicate that the MHC class III gene LST1 5' untranslated regions (5'-UTR) contains several upstream open reading frames (uORFs).

  3. Psoriasis was associated with promoter variant, rs9267502 of LST1 (show NFKBIL1 Proteins).Promoter activity was examined and it was larger than that of the other genetic variants, most probably due to changes in binding affinity to transcription factors.

  4. This is the first report demonstrating regulated LST1 (show NFKBIL1 Proteins) expression in human intestinal epithelial and microvascular endothelial cells and in inflamed colonic tissue from IBD patients.

  5. LST1 is expressed specifically in leukocytes of the myeloid lineage, where it localizes to the tetraspanin-enriched microdomains andit binds SHP-1 and SHP-2 phosphatases.

  6. Study found association between extended LTA (show LTA Proteins), TNF (show TNF Proteins), LST1 (show NFKBIL1 Proteins) and HLA gene haplotypes and rubella vaccine-induced immunity.

  7. Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 (show NCR3 Proteins) receptor by activated NK cells.

  8. Expression of this receptor, inhibited by TGF-beta1 (show TGFB1 Proteins), affects NK-mediated killing of dendritic cells

  9. The expression of LST1 (show NFKBIL1 Proteins), specifically splice variants encoding soluble isoforms and NCR3 (show NCR3 Proteins), was increased in rheumatoid-arthritis-affected blood and synovium and was associated with more severe inflammation in the synovium.

  10. LST1 (show NFKBIL1 Proteins) protein expression in human cell lines was found to be tightly regulated, allowing the expression of transmembrane isoforms but suppressing soluble isoforms

Mouse (Murine) Leukocyte Specific Transcript 1 (LST1) interaction partners

  1. The absence of Lst1 leads to a slightly more susceptible phenotype. However, deletion of Lst1 in DBA (show RPS19 Proteins)/2 J mice alone does not explain the high susceptibility of this strain to PR8M influenza infections.

LST1 Protein Profile

Protein Summary

The protein encoded by this gene is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LST1

  • leukocyte specific transcript 1 (LST1)
  • leukocyte specific transcript 1 (Lst1)
  • B144 protein
  • D6S49E protein
  • LST-1 protein

Protein level used designations for LST1

leukocyte-specific transcript 1 protein , lymphocyte antigen 117 , leucocyte specific transcript 1

7940 Homo sapiens
16988 Mus musculus
64569 Rattus norvegicus
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